Gene Locus : musdo-EST23aes07
Mode of mutation : Natural mutant
Disease :
Summary : OP-resistance increases OP hydrolase activity (E3-Rmal Malathion and dimethyl OP) Taskin_2004_Genetika_40_478
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : OP-resistance
Torpedo_number : 233
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
p.Trp251Ser n.G752C . increases OP hydrolase activity (E3-Rmal Malathion and dimethyl OP). || Malathion resistance Zhang et al.2018 For S250T W251S M303I L334L W378R S383T majority of female carried the homozygous susceptible allele in susceptible strain while males were primary heterozygous for these alleles. In resistant strains both male and females were homozygous for the mutation. W found also in some resistant strains Zhang et al. 2010 Claudianos 1999 (Rutgers)
| Title : Multiple Genetic Mutations Related to Insecticide Resistance are Detected in Field Kazakhstani House Flies (Muscidae: Diptera) - Qu_2021_J.Med.Entomol__ |
| Author(s) : Qu R , Zhu J , Li M , Jashenko R , Qiu X |
| Ref : Journal of Medical Entomology , : , 2021 |
| Abstract : |
| PubMedSearch : Qu_2021_J.Med.Entomol__ |
| PubMedID: 34197608 |
| Title : Multiple mutations and overexpression of the MdaE7 carboxylesterase gene associated with male-linked malathion resistance in housefly, Musca domestica (Diptera: Muscidae) - Zhang_2018_Sci.Rep_8_224 |
| Author(s) : Zhang Y , Li J , Ma Z , Shan C , Gao X |
| Ref : Sci Rep , 8 :224 , 2018 |
| Abstract : |
| PubMedSearch : Zhang_2018_Sci.Rep_8_224 |
| PubMedID: 29317643 |
| Gene_locus related to this paper: musdo-EST23aes07 |
| Title : Quantitative and qualitative changes of the carboxylesterase associated with beta-cypermethrin resistance in the housefly, Musca domestica (Diptera: Muscidae) - Zhang_2010_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_156_6 |
| Author(s) : Zhang L , Shi J , Shi X , Liang P , Gao J , Gao X |
| Ref : Comparative Biochemistry & Physiology B Biochem Mol Biol , 156 :6 , 2010 |
| Abstract : |
| PubMedSearch : Zhang_2010_Comp.Biochem.Physiol.B.Biochem.Mol.Biol_156_6 |
| PubMedID: 20117228 |
| Gene_locus related to this paper: musdo-EST23aes07 |
| Title : Partial base sequence analysis of Md[alpha]E7 gene and ali-esterase enzyme activities in field collected populations of house fly (Musca domestica L.) from Mediterranean and Aegean Regions of Turkey - Gacar_2009_Pestic.Biochem.Physiol_94_86 |
| Author(s) : Gacar F , Taskin V |
| Ref : Pesticide Biochemistry and Physiology , 94 :86 , 2009 |
| Abstract : |
| PubMedSearch : Gacar_2009_Pestic.Biochem.Physiol_94_86 |
| PubMedID: |
| Gene_locus related to this paper: musdo-EST23aes07 |
| Title : The genetic basis of malathion resistance in housefly (Musca domestica L.) strains from Turkey - Taskin_2004_Genetika_40_1475 |
| Author(s) : Taskin V , Kence M |
| Ref : Genetika , 40 :1475 , 2004 |
| Abstract : |
| PubMedSearch : Taskin_2004_Genetika_40_1475 |
| PubMedID: 15612566 |
| Gene_locus related to this paper: musdo-EST23aes07 |
| Title : Determination of malathion and diazinon resistance by sequencing the Md alpha E7 gene from Guatemala, Colombia, Manhattan, and Thailand housefly (Musca domestica L.) strains - Taskin_2004_Genetika_40_478 |
| Author(s) : Taskin V , Kence M , Gocmen B |
| Ref : Genetika , 40 :478 , 2004 |
| Abstract : |
| PubMedSearch : Taskin_2004_Genetika_40_478 |
| PubMedID: 15174280 |
| Title : The house fly aliesterase gene (MdalphaE7) is not associated with insecticide resistance or P450 expression in three strains of house fly - Scott_2003_Insect.Biochem.Mol.Biol_33_139 |
| Author(s) : Scott JG , Zhang L |
| Ref : Insect Biochemistry & Molecular Biology , 33 :139 , 2003 |
| Abstract : |
| PubMedSearch : Scott_2003_Insect.Biochem.Mol.Biol_33_139 |
| PubMedID: 12535672 |
| Gene_locus related to this paper: musdo-EST23aes07 |
| Title : The same amino acid substitution in orthologous esterases confers organophosphate resistance on the house fly and a blowfly - Claudianos_1999_Insect.Biochem.Mol.Biol_29_675 |
| Author(s) : Claudianos C , Russell RJ , Oakeshott JG |
| Ref : Insect Biochemistry & Molecular Biology , 29 :675 , 1999 |
| Abstract : |
| PubMedSearch : Claudianos_1999_Insect.Biochem.Mol.Biol_29_675 |
| PubMedID: 10451921 |
| Gene_locus related to this paper: musdo-EST23aes07 |