E463R_eleel-ACHE

General

Gene Locus : eleel-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Fab epitope abolished inhibition by Elec-408,Putative backdoor Simon_1999_J.Biol.Chem_274_27740

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Fab epitope

Torpedo_number : 463

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
mutation with torpedo numbering. Putative backdoor || p.Glu463Arg

References (1)

Title : The binding sites of inhibitory monoclonal antibodies on acetylcholinesterase. Identification of a novel regulatory site at the putative back door - Simon_1999_J.Biol.Chem_274_27740
Author(s) : Simon S , Le Goff A , Frobert Y , Grassi J , Massoulie J
Ref : Journal of Biological Chemistry , 274 :27740 , 1999
Abstract :
PubMedSearch : Simon_1999_J.Biol.Chem_274_27740
PubMedID: 10488117