Gene Locus : human-BCHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : OP-resistance\;resistant to echothiophate \;Gnatt_1994_J.Neurochem_62_749
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : OP-resistance
Torpedo_number : 331
Kinetic Parameter : Butyrylthiocholine_F329D_human-BCHE, Echothiophate_F329D_human-BCHE, Iso-OMPA_F329D_human-BCHE, DFP_F329D_human-BCHE
News : No news
Comment : p.F329D Phe329Asp (p.F357D Phe357Asp in primary sequence with 28 amino-acids signal peptide) resistant to echothiophate
| Title : Site-directed mutagenesis of active site residues reveals plasticity of human butyrylcholinesterase in substrate and inhibitor interactions - Gnatt_1994_J.Neurochem_62_749 |
| Author(s) : Gnatt A , Loewenstein Y , Yaron A , Schwarz M , Soreq H |
| Ref : Journal of Neurochemistry , 62 :749 , 1994 |
| Abstract : Gnatt_1994_J.Neurochem_62_749 |
| ESTHER : Gnatt_1994_J.Neurochem_62_749 |
| PubMedSearch : Gnatt_1994_J.Neurochem_62_749 |
| PubMedID: 8294937 |