| Title : Enzymatic removal of carboxyl protecting groups. 2. Cleavage of the benzyl and methyl moieties - Barbayianni_2005_J.Org.Chem_70_8730 |
| Author(s) : Barbayianni E , Fotakopoulou I , Schmidt M , Constantinou-Kokotou V , Bornscheuer UT , Kokotos G |
| Ref : J Org Chem , 70 :8730 , 2005 |
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Abstract :
[reaction: see text] Enzymes are versatile reagents for the efficient removal of methyl and benzyl protecting groups. An esterase from Bacillus subtilis (BS2) and a lipase from Candida antarctica (CAL-A) allow a mild and selective removal of these moieties in high yields without affecting other functional groups. |
| PubMedSearch : Barbayianni_2005_J.Org.Chem_70_8730 |
| PubMedID: 16238302 |
Barbayianni E, Fotakopoulou I, Schmidt M, Constantinou-Kokotou V, Bornscheuer UT, Kokotos G (2005)
Enzymatic removal of carboxyl protecting groups. 2. Cleavage of the benzyl and methyl moieties
J Org Chem
70 :8730
Barbayianni E, Fotakopoulou I, Schmidt M, Constantinou-Kokotou V, Bornscheuer UT, Kokotos G (2005)
J Org Chem
70 :8730