| Title : Synthesis, phytotoxic, cytotoxic, acetylcholinesterase and butrylcholinesterase activities of N,N'-diaryl unsymmetrically substituted thioureas - Begum_2009_Nat.Prod.Res_23_1719 |
| Author(s) : Begum S , Choudhary MI , Khan KM |
| Ref : Nat Prod Res , 23 :1719 , 2009 |
|
Abstract :
Fourteen N,N'-diaryl unsymmetrically substituted thioureas were synthesised and their cytotoxic (in vitro), phytotoxic (in vitro), acetylcholinesterase and butrylcholinesterase activities were determined. Thiourea 16 exhibited high, and 1 and 3 showed significant phytotoxic activity. Thioureas 1, 3, 4, 6 and 10 showed significant activity and 2, 6 and 7 indicated moderate cytotoxic activities. Compound 12 exhibited butrylcholinesterase activity higher than a standard reference. |
| PubMedSearch : Begum_2009_Nat.Prod.Res_23_1719 |
| PubMedID: 19921590 |
Begum S, Choudhary MI, Khan KM (2009)
Synthesis, phytotoxic, cytotoxic, acetylcholinesterase and butrylcholinesterase activities of N,N'-diaryl unsymmetrically substituted thioureas
Nat Prod Res
23 :1719
Begum S, Choudhary MI, Khan KM (2009)
Nat Prod Res
23 :1719