| Title : Imidazole-thiadiazole hybrids: A multitarget de novo drug design approach, in vitro evaluation, ADME\/T, and in silico studies - Maqbool_2024_Arch.Pharm.(Weinheim)__e2400325 |
| Author(s) : Maqbool M , Solangi M , Khan KM , Ozil M , Baltas N , Salar U , Tariq SS , Haq ZU , Taha M |
| Ref : Arch Pharm (Weinheim) , :e2400325 , 2024 |
| Abstract : |
| PubMedSearch : Maqbool_2024_Arch.Pharm.(Weinheim)__e2400325 |
| PubMedID: 38885529 |
| Title : Multitargeted inhibition of key enzymes associated with diabetes and Alzheimer's disease by 1,3,4-oxadiazole derivatives: Synthesis, in vitro screening, and computational studies - Fatima_2023_Arch.Pharm.(Weinheim)__e2300384 |
| Author(s) : Fatima B , Saleem F , Salar U , Chigurupati S , Felemban SG , Ul-Haq Z , Tariq SS , Almahmoud SA , Taha M , Shah STA , Khan KM |
| Ref : Arch Pharm (Weinheim) , :e2300384 , 2023 |
| Abstract : |
| PubMedSearch : Fatima_2023_Arch.Pharm.(Weinheim)__e2300384 |
| PubMedID: 37806747 |
| Title : Synthesis, DFT Studies, Molecular Docking and Biological Activity Evaluation of Thiazole-Sulfonamide Derivatives as Potent Alzheimer's Inhibitors - Khan_2023_Molecules_28_9062 |
| Author(s) : Khan S , Ullah H , Taha M , Rahim F , Sarfraz M , Iqbal R , Iqbal N , Hussain R , Ali Shah SA , Ayub K , Albalawi MA , Abdelaziz MA , Alatawi FS , Khan KM |
| Ref : Molecules , 28 :9062 , 2023 |
| Abstract : |
| PubMedSearch : Khan_2023_Molecules_28_9062 |
| PubMedID: 36677616 |
| Title : Evaluation of synthetic 2-aryl quinoxaline derivatives as alpha-amylase, alpha-glucosidase, acetylcholinesterase, and butyrylcholinesterase inhibitors - Hameed_2022_Int.J.Biol.Macromol_211_653 |
| Author(s) : Hameed S , Khan KM , Taslimi P , Salar U , Taskin-Tok T , Kisa D , Saleem F , Solangi M , Ahmed MHU , Rani K |
| Ref : Int J Biol Macromol , 211 :653 , 2022 |
| Abstract : |
| PubMedSearch : Hameed_2022_Int.J.Biol.Macromol_211_653 |
| PubMedID: 35568155 |
| Title : Synthesis of New Triazole-Based Thiosemicarbazone Derivatives as Anti-Alzheimer's Disease Candidates: Evidence-Based In Vitro Study - Rahim_2022_Molecules_28_ |
| Author(s) : Rahim F , Ullah H , Taha M , Hussain R , Sarfraz M , Iqbal R , Iqbal N , Khan S , Ali Shah SA , Albalawi MA , Abdelaziz MA , Alatawi FS , Alasmari A , Sakran MI , Zidan N , Jafri I , Khan KM |
| Ref : Molecules , 28 : , 2022 |
| Abstract : |
| PubMedSearch : Rahim_2022_Molecules_28_ |
| PubMedID: 36615218 |
| Title : Efficient one-pot synthesis of arylated pyrazole-fused pyran analogs: as leads to treating diabetes and Alzheimer's disease - Hameed_2022_Future.Med.Chem__ |
| Author(s) : Hameed S , Babatunde O , Salar U , Jabbar A , Chigurupati S , Solangi M , Atta L , Ul-Haq Z , Saleem F , Bhatia S , Al-Harrasi A , Taha M , Khan KM |
| Ref : Future Med Chem , : , 2022 |
| Abstract : |
| PubMedSearch : Hameed_2022_Future.Med.Chem__ |
| PubMedID: 36268762 |
| Title : Synthesis of indole derivatives as Alzheimer inhibitors and their molecular docking study - Homoud_2022_J.Biomol.Struct.Dyn__1 |
| Author(s) : Homoud ZA , Taha M , Rahim F , Iqbal N , Nawaz M , Farooq RK , Wadood A , Alomari M , Islam I , Algheribe S , Rehman AU , Khan KM , Uddin N |
| Ref : J Biomol Struct Dyn , :1 , 2022 |
| Abstract : |
| PubMedSearch : Homoud_2022_J.Biomol.Struct.Dyn__1 |
| PubMedID: 36404604 |
| Title : Synthesis, in vitro biological screening and docking study of benzo[d]oxazole bis Schiff base derivatives as a potent anti-Alzheimer agent - Taha_2022_J.Biomol.Struct.Dyn__1 |
| Author(s) : Taha M , Rahim F , Zaman K , Anouar EH , Uddin N , Nawaz F , Sajid M , Khan KM , Shah AA , Wadood A , Rehman AU , Alhibshi AH |
| Ref : J Biomol Struct Dyn , :1 , 2022 |
| Abstract : |
| PubMedSearch : Taha_2022_J.Biomol.Struct.Dyn__1 |
| PubMedID: 34989316 |
| Title : Exploring indole-based-thiadiazole derivatives as potent acetylcholinesterase and butyrylcholinesterase enzyme inhibitors - Taha_2021_Int.J.Biol.Macromol__ |
| Author(s) : Taha M , Rahim F , Uddin N , Khan IU , Iqbal N , Anouar EH , Salahuddin M , Farooq RK , Gollapalli M , Khan KM , Zafar A |
| Ref : Int J Biol Macromol , : , 2021 |
| Abstract : |
| PubMedSearch : Taha_2021_Int.J.Biol.Macromol__ |
| PubMedID: 34390751 |
| Title : Biology-oriented drug synthesis and evaluation of secnidazole esters as novel enzyme inhibitors - Ansari_2021_Arch.Pharm.(Weinheim)__e2100376 |
| Author(s) : Ansari MA , Saad SM , Khan KM , Salar U , Taslimi P , Taskin-Tok T , Saleem F , Jahangir S |
| Ref : Arch Pharm (Weinheim) , :e2100376 , 2021 |
| Abstract : |
| PubMedSearch : Ansari_2021_Arch.Pharm.(Weinheim)__e2100376 |
| PubMedID: 34862640 |
| Title : UHPLC-MS Phytochemical profiling, biological propensities and in-silico studies of Alhagi maurorum roots: A medicinal herb with multifunctional properties - Saleem_2020_Drug.Dev.Ind.Pharm__1 |
| Author(s) : Saleem H , Sarfaraz M , Khan KM , Anwar MI , Zengin G , Ahmad I , Khan SU , Mahomoodally FM , Ahemad N |
| Ref : Drug Dev Ind Pharm , :1 , 2020 |
| Abstract : |
| PubMedSearch : Saleem_2020_Drug.Dev.Ind.Pharm__1 |
| PubMedID: 32352878 |
| Title : Synthesis, structure-activity relationship and molecular docking studies of 3-O-flavonol glycosides as cholinesterase inhibitors - Mughal_2018_Bioorg.Med.Chem_26_3696 |
| Author(s) : Mughal EU , Javid A , Sadiq A , Murtaza S , Zafar MN , Khan BA , Sumrra SH , Tahir MN , Kanwal , Khan KM |
| Ref : Bioorganic & Medicinal Chemistry , 26 :3696 , 2018 |
| Abstract : |
| PubMedSearch : Mughal_2018_Bioorg.Med.Chem_26_3696 |
| PubMedID: 29886083 |
| Title : Modification of Bischler-Mohlau indole derivatives through palladium catalyzed Suzuki reaction as effective cholinesterase inhibitors, their kinetic and molecular docking studies - Parveen_2017_Bioorg.Chem_76_166 |
| Author(s) : Parveen S , Shah MS , Zaib S , Gul T , Khan KM , Iqbal J , Hassan A |
| Ref : Bioorg Chem , 76 :166 , 2017 |
| Abstract : |
| PubMedSearch : Parveen_2017_Bioorg.Chem_76_166 |
| PubMedID: 29175588 |
| Title : Synthesis, structure-activity relationship and molecular docking of 3-oxoaurones and 3-thioaurones as acetylcholinesterase and butyrylcholinesterase inhibitors - Mughal_2017_Bioorg.Med.Chem_25_100 |
| Author(s) : Mughal EU , Sadiq A , Murtaza S , Rafique H , Zafar MN , Riaz T , Khan BA , Hameed A , Khan KM |
| Ref : Bioorganic & Medicinal Chemistry , 25 :100 , 2017 |
| Abstract : |
| PubMedSearch : Mughal_2017_Bioorg.Med.Chem_25_100 |
| PubMedID: 27780618 |
| Title : One-pot synthesis of tetrazole-1,2,5,6-tetrahydronicotinonitriles and cholinesterase inhibition: Probing the plausible reaction mechanism via computational studies - Hameed_2016_Bioorg.Chem_65_38 |
| Author(s) : Hameed A , Zehra ST , Abbas S , Nisa RU , Mahmood T , Ayub K , Al-Rashida M , Bajorath J , Khan KM , Iqbal J |
| Ref : Bioorg Chem , 65 :38 , 2016 |
| Abstract : |
| PubMedSearch : Hameed_2016_Bioorg.Chem_65_38 |
| PubMedID: 26851737 |
| Title : Synthesis and in vitro acetylcholinesterase and butyrylcholinesterase inhibitory potential of hydrazide based Schiff bases - Rahim_2016_Bioorg.Chem_68_30 |
| Author(s) : Rahim F , Ullah H , Taha M , Wadood A , Javed MT , Rehman W , Nawaz M , Ashraf M , Ali M , Sajid M , Ali F , Khan MN , Khan KM |
| Ref : Bioorg Chem , 68 :30 , 2016 |
| Abstract : |
| PubMedSearch : Rahim_2016_Bioorg.Chem_68_30 |
| PubMedID: 27441832 |
| Title : Synthesis, molecular docking, acetylcholinesterase and butyrylcholinesterase inhibitory potential of thiazole analogs as new inhibitors for Alzheimer disease - Rahim_2015_Bioorg.Chem_62_106 |
| Author(s) : Rahim F , Javed MT , Ullah H , Wadood A , Taha M , Ashraf M , Qurat Ul A , Khan MA , Khan F , Mirza S , Khan KM |
| Ref : Bioorg Chem , 62 :106 , 2015 |
| Abstract : |
| PubMedSearch : Rahim_2015_Bioorg.Chem_62_106 |
| PubMedID: 26318401 |
| Title : Syntheses, Cholinesterases Inhibition, and Molecular Docking Studies of Pyrido[2,3-b]pyrazine Derivatives - Hameed_2015_Chem.Biol.Drug.Des_86_1115 |
| Author(s) : Hameed A , Zehra ST , Shah SJ , Khan KM , Alharthy RD , Furtmann N , Bajorath J , Tahir MN , Iqbal J |
| Ref : Chemical Biology Drug Des , 86 :1115 , 2015 |
| Abstract : |
| PubMedSearch : Hameed_2015_Chem.Biol.Drug.Des_86_1115 |
| PubMedID: 25951978 |
| Title : Synthesis of triazole Schiff bases: Novel inhibitors of nucleotide pyrophosphatase\/phosphodiesterase-1 - Khan_2014_Bioorg.Med.Chem_22_6509 |
| Author(s) : Khan KM , Siddiqui S , Saleem M , Taha M , Saad SM , Perveen S , Choudhary MI |
| Ref : Bioorganic & Medicinal Chemistry , 22 :6509 , 2014 |
| Abstract : |
| PubMedSearch : Khan_2014_Bioorg.Med.Chem_22_6509 |
| PubMedID: 25440732 |
| Title : Synthesis, characterization and biological screening of 5-substituted-1,3,4-oxadiazole-2yl-N-(2-methoxy-5-chlorophenyl)-2-sulfanyl acetamide - Rehman_2013_Pak.J.Pharm.Sci_26_345 |
| Author(s) : Rehman A , Fatima A , Abbas N , Abbasi MA , Khan KM , Ashraf M , Ahmad I , Ejaz SA |
| Ref : Pak J Pharm Sci , 26 :345 , 2013 |
| Abstract : |
| PubMedSearch : Rehman_2013_Pak.J.Pharm.Sci_26_345 |
| PubMedID: 23455206 |
| Title : Antioxidant and lipoxygenase inhibiting new iridoid glucosides from Caryopteris odorata - Shahzadi_2013_Nat.Prod.Res_27_302 |
| Author(s) : Shahzadi T , Abbasi MA , Ur-Rehman A , Riaz T , Khan KM , Ashraf M , Afzal I , Akhtar MN , Ajaib M |
| Ref : Nat Prod Res , 27 :302 , 2013 |
| Abstract : |
| PubMedSearch : Shahzadi_2013_Nat.Prod.Res_27_302 |
| PubMedID: 22424117 |
| Title : Synthesis, characterization and biological screening of sulfonamides derived form 2-phenylethylamine - Rehman_2012_Pak.J.Pharm.Sci_25_809 |
| Author(s) : Rehman AU , Afroz S , Abbasi MA , Tanveer W , Khan KM , Ashraf M , Ahmad I , Afzal I , Ambreen N |
| Ref : Pak J Pharm Sci , 25 :809 , 2012 |
| Abstract : |
| PubMedSearch : Rehman_2012_Pak.J.Pharm.Sci_25_809 |
| PubMedID: 23009998 |
| Title : Synthesis, phytotoxic, cytotoxic, acetylcholinesterase and butrylcholinesterase activities of N,N'-diaryl unsymmetrically substituted thioureas - Begum_2009_Nat.Prod.Res_23_1719 |
| Author(s) : Begum S , Choudhary MI , Khan KM |
| Ref : Nat Prod Res , 23 :1719 , 2009 |
| Abstract : |
| PubMedSearch : Begum_2009_Nat.Prod.Res_23_1719 |
| PubMedID: 19921590 |
| Title : Synthesis and inhibitory potential towards acetylcholinesterase, butyrylcholinesterase and lipoxygenase of some variably substituted chalcones - Hasan_2005_J.Enzyme.Inhib.Med.Chem_20_41 |
| Author(s) : Hasan A , Khan KM , Sher M , Maharvi GM , Nawaz SA , Choudhary MI , Atta ur R , Supuran CT |
| Ref : J Enzyme Inhib Med Chem , 20 :41 , 2005 |
| Abstract : |
| PubMedSearch : Hasan_2005_J.Enzyme.Inhib.Med.Chem_20_41 |
| PubMedID: 15895683 |
| Title : Analysis of nicotinic acetylcholine receptor subunits in the cochlea of the mouse - Drescher_1995_Comp.Biochem.Physiol.C.Pharmacol.Toxicol.Endocrinol_112_267 |
| Author(s) : Drescher DG , Khan KM , Green GE , Morley BJ , Beisel KW , Kaul H , Gordon D , Gupta AK , Drescher MJ , Barretto RL |
| Ref : Comparative Biochemistry & Physiology C Pharmacol Toxicol Endocrinol , 112 :267 , 1995 |
| Abstract : |
| PubMedSearch : Drescher_1995_Comp.Biochem.Physiol.C.Pharmacol.Toxicol.Endocrinol_112_267 |
| PubMedID: 8838678 |
| Title : Acetylcholinesterase activity is associated with efferent endings in the sensory epithelia of the utricle and semicircular canals of the rainbow trout inner ear - Khan_1993_Anat.Rec_237_141 |
| Author(s) : Khan KM , Drescher MJ , Hatfield JS , Drescher DG |
| Ref : Anatomical Record , 237 :141 , 1993 |
| Abstract : |
| PubMedSearch : Khan_1993_Anat.Rec_237_141 |
| PubMedID: 8214639 |