| Title : The thyroglobulin gene resides on chromosome 8 in man and on chromosome 7 in the rat - Brocas_1985_Cytogenet.Cell.Genet_39_150 |
| Author(s) : Brocas H , Szpirer J , Lebo RV , Levan G , Szpirer C , Cheung MC , Vassart G |
| Ref : Cytogenet Cell Genet , 39 :150 , 1985 |
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Abstract :
Human chromosomes were separated by a dual laser FACS sorter and their DNA hybridized with a thyroglobulin gene probe. A strong hybridization signal was obtained with DNA from chromosome 8. A panel of mouse-rat cell hybrids was used to determine the chromosomal localization of the rat thyroglobulin gene by the Southern blotting method. Comparison of the cytogenetic data with the hybridization signals obtained with the rat thyroglobulin probe allowed assignment of this gene to rat chromosome 7. It is concluded that the synteny relationship between the thyroglobulin gene and the c-myc oncogene has been conserved in rat and man. |
| PubMedSearch : Brocas_1985_Cytogenet.Cell.Genet_39_150 |
| PubMedID: 4006519 |
Brocas H, Szpirer J, Lebo RV, Levan G, Szpirer C, Cheung MC, Vassart G (1985)
The thyroglobulin gene resides on chromosome 8 in man and on chromosome 7 in the rat
Cytogenet Cell Genet
39 :150
Brocas H, Szpirer J, Lebo RV, Levan G, Szpirer C, Cheung MC, Vassart G (1985)
Cytogenet Cell Genet
39 :150