Title : Creation of a lipase highly selective for trans fatty acids by protein engineering - Brundiek_2012_Angew.Chem.Int.Ed.Engl_51_412 |
Author(s) : Brundiek HB , Evitt AS , Kourist R , Bornscheuer UT |
Ref : Angew Chem Int Ed Engl , 51 :412 , 2012 |
Abstract :
Sorting out: Protein engineering of lipase CAL-A led to the discovery of mutants with excellent chemoselectivity for the removal of trans and saturated fatty acids from partially hydrogenated vegetable oil. These fatty acids, identified as a major risk factor for human health, can now be removed by enzyme catalysis. |
PubMedSearch : Brundiek_2012_Angew.Chem.Int.Ed.Engl_51_412 |
PubMedID: 22113941 |
Gene_locus related to this paper: canan-lipasA |
Gene_locus | canan-lipasA |
Family | Fungal-Bact_LIP |
Brundiek HB, Evitt AS, Kourist R, Bornscheuer UT (2012)
Creation of a lipase highly selective for trans fatty acids by protein engineering
Angew Chem Int Ed Engl
51 :412
Brundiek HB, Evitt AS, Kourist R, Bornscheuer UT (2012)
Angew Chem Int Ed Engl
51 :412