| Title : Acalculous cholecystitis is a common extrahepatic manifestation of hepatitis E and suggests a more serious condition - Cao_2023_Virol.J_20_77 |
| Author(s) : Cao X , Jiang W , Shi L , Wang Y , Chen J , Huang W , Zhang S |
| Ref : Virol J , 20 :77 , 2023 |
| Abstract : BACKGROUND: This study aimed to understand the incidence and clinical significance of acalculous cholecystitis in patients with acute hepatitis E (HE). PATIENTS AND METHODS: A single center enrolled 114 patients with acute HE. All patients underwent imaging of the gallbladder, and patients with gallstones and cholecystectomy were excluded. RESULTS: Acalculous cholecystitis was found in 66 patients (57.89%) with acute HE. The incidence in males was 63.95%, which was significantly higher than in females (39.29%) (P = 0.022). The mean length of hospital stay and the incidence of spontaneous peritonitis in patients with cholecystitis (20.12 +/- 9.43 days and 9.09%, respectively) were significantly higher than those in patients without cholecystitis (12.98 +/- 7.26 days and 0%, respectively) (P < 0.001 and P = 0.032). Albumin, total bile acid, bilirubin, cholinesterase, and prothrombin activity in patients with cholecystitis were significantly inferior to those in patients without cholecystitis (P < 0.001, P < 0.001, P < 0.001, P < 0.001 and P = 0.003, respectively). After correction by multivariate analysis, albumin and total bile acid were found to be closely related to acalculous cholecystitis in HE. CONCLUSION: Acalculous cholecystitis is very common in patients with acute HE, and may serve as a predictor of increased peritonitis, synthetic decompensation, and longer hospital stay. |
| ESTHER : Cao_2023_Virol.J_20_77 |
| PubMedSearch : Cao_2023_Virol.J_20_77 |
| PubMedID: 37095526 |
Cao X, Jiang W, Shi L, Wang Y, Chen J, Huang W, Zhang S (2023)
Acalculous cholecystitis is a common extrahepatic manifestation of hepatitis E and suggests a more serious condition
Virol J
20 :77
Cao X, Jiang W, Shi L, Wang Y, Chen J, Huang W, Zhang S (2023)
Virol J
20 :77