| Title : Influence of the radioprotective agent WR 2721 on the striatal acetylcholinesterase activity in the rat - Clarencon_1993_Brain.Res_608_155 |
| Author(s) : Clarencon D , Galonnier M , Testylier G , Fatome M |
| Ref : Brain Research , 608 :155 , 1993 |
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Abstract :
The radioprotective thiophosphate S-2(3 amino-propyl-amino) phosphorothioic acid (WR 2721) induced an early reduction of striatal acetylcholinesterase activity followed by an increase, when intraperitoneally injected to rats, although it does not cross the blood-brain barrier. These results were obtained using an original technique which allows the measurements in the same animal for several days. Transient general oxidative metabolism inhibition might affect the extra-cellular enzyme amount or its activity. |
| PubMedSearch : Clarencon_1993_Brain.Res_608_155 |
| PubMedID: 8388310 |
Clarencon D, Galonnier M, Testylier G, Fatome M (1993)
Influence of the radioprotective agent WR 2721 on the striatal acetylcholinesterase activity in the rat
Brain Research
608 :155
Clarencon D, Galonnier M, Testylier G, Fatome M (1993)
Brain Research
608 :155