Dube_1993_Pharmacol.Biochem.Behav_46_827

Reference

Title : Concurrent acute exercise alters central and peripheral responses to physostigmine - Dube_1993_Pharmacol.Biochem.Behav_46_827
Author(s) : Dube SN , Somani SM , Babu SR
Ref : Pharmacology, Biochemistry & Behavior , 46 :827 , 1993
Abstract :

This study reports the modulatory effects of physostigmine (Phy) and concurrent acute exercise on the time course of cholinesterase (ChE) activity, the rate of decarbamylation (Kd), and half-time of recovery of ChE in red blood cells (RBC) and various tissues of rats. Acute exercise equivalent to 80% VO2-max (maximal oxygen consumption) transiently increased the RBC ChE activity, whereas Phy decreased ChE activity in RBC and various tissues. Physostigmine along with concurrent acute exercise increased the Kd in RBC, brain, and heart by 56.4%, 66.7%, and 139%, respectively, compared to Phy alone. The Kd in diaphragm and muscle decreased to 14.1% and 56.2%, respectively, compared to Phy alone. The variation in Kd might be due to the effect of concurrent acute exercise on the redistribution of Phy in various tissues of rat as a result of changes in blood flow.

PubMedSearch : Dube_1993_Pharmacol.Biochem.Behav_46_827
PubMedID: 8309962

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Citations formats

Dube SN, Somani SM, Babu SR (1993)
Concurrent acute exercise alters central and peripheral responses to physostigmine
Pharmacology, Biochemistry & Behavior 46 :827

Dube SN, Somani SM, Babu SR (1993)
Pharmacology, Biochemistry & Behavior 46 :827