| Title : Calcitonin gene-related peptide, a peptide present in spinal cord motoneurons, increases the number of acetylcholine receptors in primary cultures of chick embryo myotubes - Fontaine_1986_Neurosci.Lett_71_59 |
| Author(s) : Fontaine B , Klarsfeld A , Hokfelt T , Changeux JP |
| Ref : Neuroscience Letters , 71 :59 , 1986 |
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Abstract :
Using immunohistochemical methods we show that calcitonin gene-related peptide (CGRP, a peptide encoded by the calcitonin gene) is present in chick spinal cord motoneurons. When added to cultured chicken myotubes, CGRP caused an average 1.5-fold increase in levels of surface acetylcholine receptors. Moreover, the effect of CGRP was independent of the one produced by tetrodotoxin, a blocker of membrane electrical activity but not of that caused by cholera toxin, an activator of adenylate cyclase. |
| PubMedSearch : Fontaine_1986_Neurosci.Lett_71_59 |
| PubMedID: 3491345 |
Fontaine B, Klarsfeld A, Hokfelt T, Changeux JP (1986)
Calcitonin gene-related peptide, a peptide present in spinal cord motoneurons, increases the number of acetylcholine receptors in primary cultures of chick embryo myotubes
Neuroscience Letters
71 :59
Fontaine B, Klarsfeld A, Hokfelt T, Changeux JP (1986)
Neuroscience Letters
71 :59