Changeux JP

General

Full name : Changeux Jean-Pierre

First name : Jean-Pierre

Mail : Neurobiologie Moleculaire, CNRS URA 1284, Institut Pasteur, 25 rue du Dr Roux, 75015 Paris

Zip Code :

City :

Country : France

Email : changeux@noos.fr

Phone : 33 1 45 68 88 45

Fax : 33 1 45 68 88 36

Website : \/\/en.wikipedia.org\/wiki\/Jean-Pierre_Changeux

Directory :

References (168)

Title : Do Nicotinic Receptors Modulate High-Order Cognitive Processing? - Koukouli_2020_Trends.Neurosci_43_550
Author(s) : Koukouli F , Changeux JP
Ref : Trends in Neurosciences , 43 :550 , 2020
Abstract :
PubMedSearch : Koukouli_2020_Trends.Neurosci_43_550
PubMedID: 32591156

Title : Golden Anniversary of the Nicotinic Receptor - Changeux_2020_Neuron_107_14
Author(s) : Changeux JP
Ref : Neuron , 107 :14 , 2020
Abstract :
PubMedSearch : Changeux_2020_Neuron_107_14
PubMedID: 32645305

Title : Towards a cognitive neuroscience of self-awareness - Lou_2017_Neurosci.Biobehav.Rev_83_765
Author(s) : Lou HC , Changeux JP , Rosenstand A
Ref : Neurosci Biobehav Rev , 83 :765 , 2017
Abstract :
PubMedSearch : Lou_2017_Neurosci.Biobehav.Rev_83_765
PubMedID: 27079562

Title : Climbing Brain Levels of Organisation from Genes to Consciousness - Changeux_2017_Trends.Cogn.Sci_21_168
Author(s) : Changeux JP
Ref : Trends Cogn Sci , 21 :168 , 2017
Abstract :
PubMedSearch : Changeux_2017_Trends.Cogn.Sci_21_168
PubMedID: 28161289

Title : Nicotine reverses hypofrontality in animal models of addiction and schizophrenia - Koukouli_2017_Nat.Med_23_347
Author(s) : Koukouli F , Rooy M , Tziotis D , Sailor KA , O'Neill HC , Levenga J , Witte M , Nilges M , Changeux JP , Hoeffer CA , Stitzel JA , Gutkin BS , DiGregorio DA , Maskos U
Ref : Nat Med , 23 :347 , 2017
Abstract :
PubMedSearch : Koukouli_2017_Nat.Med_23_347
PubMedID: 28112735

Title : Allosteric Modulation as a Unifying Mechanism for Receptor Function and Regulation - Changeux_2016_Cell_166_1084
Author(s) : Changeux JP , Christopoulos A
Ref : Cell , 166 :1084 , 2016
Abstract :
PubMedSearch : Changeux_2016_Cell_166_1084
PubMedID: 27565340

Title : Biased Allostery - Edelstein_2016_Biophys.J_111_902
Author(s) : Edelstein SJ , Changeux JP
Ref : Biophysical Journal , 111 :902 , 2016
Abstract :
PubMedSearch : Edelstein_2016_Biophys.J_111_902
PubMedID: 27602718

Title : Nicotinic receptors in mouse prefrontal cortex modulate ultraslow fluctuations related to conscious processing - Koukouli_2016_Proc.Natl.Acad.Sci.U.S.A_113_14823
Author(s) : Koukouli F , Rooy M , Changeux JP , Maskos U
Ref : Proc Natl Acad Sci U S A , 113 :14823 , 2016
Abstract :
PubMedSearch : Koukouli_2016_Proc.Natl.Acad.Sci.U.S.A_113_14823
PubMedID: 27911815

Title : The nicotinic alpha6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2\/3 receptors - Wieskopf_2015_Sci.Transl.Med_7_287ra72
Author(s) : Wieskopf JS , Mathur J , Limapichat W , Post MR , Al-Qazzaz M , Sorge RE , Martin LJ , Zaykin DV , Smith SB , Freitas K , Austin JS , Dai F , Zhang J , Marcovitz J , Tuttle AH , Slepian PM , Clarke S , Drenan RM , Janes J , Al Sharari S , Segall SK , Aasvang EK , Lai W , Bittner R , Richards CI , Slade GD , Kehlet H , Walker J , Maskos U , Changeux JP , Devor M , Maixner W , Diatchenko L , Belfer I , Dougherty DA , Su AI , Lummis SC , Damaj MI , Lester HA , Patapoutian A , Mogil JS
Ref : Sci Transl Med , 7 :287ra72 , 2015
Abstract :
PubMedSearch : Wieskopf_2015_Sci.Transl.Med_7_287ra72
PubMedID: 25972004

Title : The nicotinic acetylcholine receptor and its prokaryotic homologues: Structure, conformational transitions & allosteric modulation - Cecchini_2015_Neuropharmacol_96_137
Author(s) : Cecchini M , Changeux JP
Ref : Neuropharmacology , 96 :137 , 2015
Abstract :
PubMedSearch : Cecchini_2015_Neuropharmacol_96_137
PubMedID: 25529272

Title : The nicotinic acetylcholine receptor: From molecular biology to cognition -
Author(s) : Changeux JP , Corringer PJ , Maskos U
Ref : Neuropharmacology , 96 :135 , 2015
PubMedID: 25842243

Title : Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation - Sauguet_2014_Proc.Natl.Acad.Sci.U.S.A_111_966
Author(s) : Sauguet L , Shahsavar A , Poitevin F , Huon C , Menny A , Nemecz A , Haouz A , Changeux JP , Corringer PJ , Delarue M
Ref : Proc Natl Acad Sci U S A , 111 :966 , 2014
Abstract :
PubMedSearch : Sauguet_2014_Proc.Natl.Acad.Sci.U.S.A_111_966
PubMedID: 24367074

Title : Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement - Tolu_2013_Mol.Psychiatry_18_382
Author(s) : Tolu S , Eddine R , Marti F , David V , Graupner M , Pons S , Baudonnat M , Husson M , Besson M , Reperant C , Zemdegs J , Pages C , Hay YA , Lambolez B , Caboche J , Gutkin B , Gardier AM , Changeux JP , Faure P , Maskos U
Ref : Mol Psychiatry , 18 :382 , 2013
Abstract :
PubMedSearch : Tolu_2013_Mol.Psychiatry_18_382
PubMedID: 22751493

Title : Intermediate closed state for glycine receptor function revealed by cysteine cross-linking - Prevost_2013_Proc.Natl.Acad.Sci.U.S.A_110_17113
Author(s) : Prevost MS , Moraga-Cid G , Van Renterghem C , Edelstein SJ , Changeux JP , Corringer PJ
Ref : Proc Natl Acad Sci U S A , 110 :17113 , 2013
Abstract :
PubMedSearch : Prevost_2013_Proc.Natl.Acad.Sci.U.S.A_110_17113
PubMedID: 24085847

Title : Modulation of the mouse prefrontal cortex activation by neuronal nicotinic receptors during novelty exploration but not by exploration of a familiar environment - Bourgeois_2012_Cereb.Cortex_22_1007
Author(s) : Bourgeois JP , Meas-Yeadid V , Lesourd AM , Faure P , Pons S , Maskos U , Changeux JP , Olivo-Marin JC , Granon S
Ref : Cerebral Cortex , 22 :1007 , 2012
Abstract :
PubMedSearch : Bourgeois_2012_Cereb.Cortex_22_1007
PubMedID: 21810785

Title : X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel - Nury_2011_Nature_469_428
Author(s) : Nury H , Van Renterghem C , Weng Y , Tran A , Baaden M , Dufresne V , Changeux JP , Sonner JM , Delarue M , Corringer PJ
Ref : Nature , 469 :428 , 2011
Abstract :
PubMedSearch : Nury_2011_Nature_469_428
PubMedID: 21248852

Title : Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine - Exley_2011_Proc.Natl.Acad.Sci.U.S.A_108_7577
Author(s) : Exley R , Maubourguet N , David V , Eddine R , Evrard A , Pons S , Marti F , Threlfell S , Cazala P , McIntosh JM , Changeux JP , Maskos U , Cragg SJ , Faure P
Ref : Proc Natl Acad Sci U S A , 108 :7577 , 2011
Abstract :
PubMedSearch : Exley_2011_Proc.Natl.Acad.Sci.U.S.A_108_7577
PubMedID: 21502501

Title : Prefrontal nicotinic receptors control novel social interaction between mice - Avale_2011_FASEB.J_25_2145
Author(s) : Avale ME , Chabout J , Pons S , Serreau P , De Chaumont F , Olivo-Marin JC , Bourgeois JP , Maskos U , Changeux JP , Granon S
Ref : FASEB Journal , 25 :2145 , 2011
Abstract :
PubMedSearch : Avale_2011_FASEB.J_25_2145
PubMedID: 21402717

Title : A versatile system for the neuronal subtype specific expression of lentiviral vectors - Tolu_2010_FASEB.J_24_723
Author(s) : Tolu S , Avale ME , Nakatani H , Pons S , Parnaudeau S , Tronche F , Vogt A , Monyer H , Vogel R , De Chaumont F , Olivo-Marin JC , Changeux JP , Maskos U
Ref : FASEB Journal , 24 :723 , 2010
Abstract :
PubMedSearch : Tolu_2010_FASEB.J_24_723
PubMedID: 19858094

Title : One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue - Nury_2010_Proc.Natl.Acad.Sci.U.S.A_107_6275
Author(s) : Nury H , Poitevin F , Van Renterghem C , Changeux JP , Corringer PJ , Delarue M , Baaden M
Ref : Proc Natl Acad Sci U S A , 107 :6275 , 2010
Abstract :
PubMedSearch : Nury_2010_Proc.Natl.Acad.Sci.U.S.A_107_6275
PubMedID: 20308576

Title : Relationships between structural dynamics and functional kinetics in oligomeric membrane receptors - Edelstein_2010_Biophys.J_98_2045
Author(s) : Edelstein SJ , Changeux JP
Ref : Biophysical Journal , 98 :2045 , 2010
Abstract :
PubMedSearch : Edelstein_2010_Biophys.J_98_2045
PubMedID: 20483311

Title : alpha-Conotoxin BuIA[T5A\;P6O]: a novel ligand that discriminates between alpha6ss4 and alpha6ss2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release - Azam_2010_FASEB.J_24_5113
Author(s) : Azam L , Maskos U , Changeux JP , Dowell CD , Christensen S , De Biasi M , McIntosh JM
Ref : FASEB Journal , 24 :5113 , 2010
Abstract :
PubMedSearch : Azam_2010_FASEB.J_24_5113
PubMedID: 20739611

Title : Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system - Taly_2009_Nat.Rev.Drug.Discov_8_733
Author(s) : Taly A , Corringer PJ , Guedin D , Lestage P , Changeux JP
Ref : Nat Rev Drug Discov , 8 :733 , 2009
Abstract :
PubMedSearch : Taly_2009_Nat.Rev.Drug.Discov_8_733
PubMedID: 19721446

Title : Regional changes in the cholinergic system in mice lacking monoamine oxidase A - Grailhe_2009_Brain.Res.Bull_78_283
Author(s) : Grailhe R , Cardona A , Even N , Seif I , Changeux JP , Cloez-Tayarani I
Ref : Brain Research Bulletin , 78 :283 , 2009
Abstract :
PubMedSearch : Grailhe_2009_Brain.Res.Bull_78_283
PubMedID: 19111597

Title : Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration - Pons_2008_J.Neurosci_28_12318
Author(s) : Pons S , Fattore L , Cossu G , Tolu S , Porcu E , McIntosh JM , Changeux JP , Maskos U , Fratta W
Ref : Journal of Neuroscience , 28 :12318 , 2008
Abstract :
PubMedSearch : Pons_2008_J.Neurosci_28_12318
PubMedID: 19020025

Title : Behavioral sequence analysis reveals a novel role for beta2* nicotinic receptors in exploration - Maubourguet_2008_PLoS.Comput.Biol_4_e1000229
Author(s) : Maubourguet N , Lesne A , Changeux JP , Maskos U , Faure P
Ref : PLoS Comput Biol , 4 :e1000229 , 2008
Abstract :
PubMedSearch : Maubourguet_2008_PLoS.Comput.Biol_4_e1000229
PubMedID: 19023420

Title : Nicotinic acetylcholine receptor-subunit mRNAs in the mouse superior cervical ganglion are regulated by development but not by deletion of distinct subunit genes - Putz_2008_J.Neurosci.Res_86_972
Author(s) : Putz G , Kristufek D , Orr-Urtreger A , Changeux JP , Huck S , Scholze P
Ref : Journal of Neuroscience Research , 86 :972 , 2008
Abstract :
PubMedSearch : Putz_2008_J.Neurosci.Res_86_972
PubMedID: 17975828

Title : Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs - Jackson_2008_J.Pharmacol.Exp.Ther_325_302
Author(s) : Jackson KJ , Martin BR , Changeux JP , Damaj MI
Ref : Journal of Pharmacology & Experimental Therapeutics , 325 :302 , 2008
Abstract :
PubMedSearch : Jackson_2008_J.Pharmacol.Exp.Ther_325_302
PubMedID: 18184829

Title : Interplay of beta2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion - Avale_2008_Proc.Natl.Acad.Sci.U.S.A_105_15991
Author(s) : Avale ME , Faure P , Pons S , Robledo P , Deltheil T , David DJ , Gardier AM , Maldonado R , Granon S , Changeux JP , Maskos U
Ref : Proc Natl Acad Sci U S A , 105 :15991 , 2008
Abstract :
PubMedSearch : Avale_2008_Proc.Natl.Acad.Sci.U.S.A_105_15991
PubMedID: 18832468

Title : A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family - Bocquet_2007_Nature_445_116
Author(s) : Bocquet N , Prado de Carvalho L , Cartaud J , Neyton J , Le Poupon C , Taly A , Grutter T , Changeux JP , Corringer PJ
Ref : Nature , 445 :116 , 2007
Abstract :
PubMedSearch : Bocquet_2007_Nature_445_116
PubMedID: 17167423

Title : The role of nicotinic receptors in B-lymphocyte development and activation - Skok_2007_Life.Sci_80_2334
Author(s) : Skok MV , Grailhe R , Agenes F , Changeux JP
Ref : Life Sciences , 80 :2334 , 2007
Abstract :
PubMedSearch : Skok_2007_Life.Sci_80_2334
PubMedID: 17363009

Title : Intracellular complexes of the beta2 subunit of the nicotinic acetylcholine receptor in brain identified by proteomics - Kabbani_2007_Proc.Natl.Acad.Sci.U.S.A_104_20570
Author(s) : Kabbani N , Woll MP , Levenson R , Lindstrom JM , Changeux JP
Ref : Proc Natl Acad Sci U S A , 104 :20570 , 2007
Abstract :
PubMedSearch : Kabbani_2007_Proc.Natl.Acad.Sci.U.S.A_104_20570
PubMedID: 18077321

Title : Loss of high-affinity nicotinic receptors increases the vulnerability to excitotoxic lesion and decreases the positive effects of an enriched environment - Zanardi_2007_FASEB.J_21_4028
Author(s) : Zanardi A , Ferrari R , Leo G , Maskos U , Changeux JP , Zoli M
Ref : FASEB Journal , 21 :4028 , 2007
Abstract :
PubMedSearch : Zanardi_2007_FASEB.J_21_4028
PubMedID: 17622669

Title : Catecholamine outflow from mouse and rat brain slice preparations evoked by nicotinic acetylcholine receptor activation and electrical field stimulation - Scholze_2007_Br.J.Pharmacol_151_414
Author(s) : Scholze P , Orr-Urtreger A , Changeux JP , McIntosh JM , Huck S
Ref : British Journal of Pharmacology , 151 :414 , 2007
Abstract :
PubMedSearch : Scholze_2007_Br.J.Pharmacol_151_414
PubMedID: 17401441

Title : Evaluating the suitability of nicotinic acetylcholine receptor antibodies for standard immunodetection procedures - Moser_2007_J.Neurochem_102_479
Author(s) : Moser N , Mechawar N , Jones I , Gochberg-Sarver A , Orr-Urtreger A , Plomann M , Salas R , Molles BE , Marubio L , Roth U , Maskos U , Winzer-Serhan U , Bourgeois JP , Le Sourd AM , De Biasi M , Schroder H , Lindstrom JM , Maelicke A , Changeux JP , Wevers A
Ref : Journal of Neurochemistry , 102 :479 , 2007
Abstract :
PubMedSearch : Moser_2007_J.Neurochem_102_479
PubMedID: 17419810

Title : Identification of two critical residues within the Cys-loop sequence that determine fast-gating kinetics in a pentameric ligand-gated ion channel - Grutter_2006_J.Mol.Neurosci_30_63
Author(s) : Grutter T , de Carvalho LP , Dufresne V , Taly A , Changeux JP
Ref : Journal of Molecular Neuroscience , 30 :63 , 2006
Abstract :
PubMedSearch : Grutter_2006_J.Mol.Neurosci_30_63
PubMedID: 17192629

Title : Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors - Mameli-Engvall_2006_Neuron_50_911
Author(s) : Mameli-Engvall M , Evrard A , Pons S , Maskos U , Svensson TH , Changeux JP , Faure P
Ref : Neuron , 50 :911 , 2006
Abstract :
PubMedSearch : Mameli-Engvall_2006_Neuron_50_911
PubMedID: 16772172

Title : Nicotine enhances intracellular nicotinic receptor maturation: A novel mechanism of neural plasticity? - Corringer_2006_J.Physiol.Paris_99_162
Author(s) : Corringer PJ , Sallette J , Changeux JP
Ref : Journal de Physiologie (Paris) , 99 :162 , 2006
Abstract :
PubMedSearch : Corringer_2006_J.Physiol.Paris_99_162
PubMedID: 16458492

Title : Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors - Taly_2006_Proc.Natl.Acad.Sci.U.S.A_103_16965
Author(s) : Taly A , Corringer PJ , Grutter T , Prado de Carvalho L , Karplus M , Changeux JP
Ref : Proc Natl Acad Sci U S A , 103 :16965 , 2006
Abstract :
PubMedSearch : Taly_2006_Proc.Natl.Acad.Sci.U.S.A_103_16965
PubMedID: 17077146

Title : Targeted in vivo expression of nicotinic acetylcholine receptors in mouse brain using lentiviral expression vectors - Molles_2006_J.Mol.Neurosci_30_105
Author(s) : Molles BE , Maskos U , Pons S , Besson M , Guiard P , Guilloux JP , Evrard A , Cormier A , Mameli-Engvall M , Cloez-Tayarani I , Nakatani H , Dufour N , Bemelmans AP , Mallet J , Cazala P , Gardier AM , David V , Faure P , Granon S , Changeux JP
Ref : Journal of Molecular Neuroscience , 30 :105 , 2006
Abstract :
PubMedSearch : Molles_2006_J.Mol.Neurosci_30_105
PubMedID: 17192649

Title : Inhibition of both alpha7* and beta2* nicotinic acetylcholine receptors is necessary to prevent development of sensitization to cocaine-elicited increases in extracellular dopamine levels in the ventral striatum - Zanetti_2006_Psychopharmacology.(Berl)_187_181
Author(s) : Zanetti L , de Kerchove d'Exaerde A , Zanardi A , Changeux JP , Picciotto MR , Zoli M
Ref : Psychopharmacology (Berl) , 187 :181 , 2006
Abstract :
PubMedSearch : Zanetti_2006_Psychopharmacology.(Berl)_187_181
PubMedID: 16826402

Title : The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice - Walters_2006_Psychopharmacology.(Berl)_184_339
Author(s) : Walters CL , Brown S , Changeux JP , Martin B , Damaj MI
Ref : Psychopharmacology (Berl) , 184 :339 , 2006
Abstract :
PubMedSearch : Walters_2006_Psychopharmacology.(Berl)_184_339
PubMedID: 16416156

Title : Live imaging of neural structure and function by fibred fluorescence microscopy - Vincent_2006_EMBO.Rep_7_1154
Author(s) : Vincent P , Maskos U , Charvet I , Bourgeais L , Stoppini L , Leresche N , Changeux JP , Lambert R , Meda P , Paupardin-Tritsch D
Ref : EMBO Rep , 7 :1154 , 2006
Abstract :
PubMedSearch : Vincent_2006_EMBO.Rep_7_1154
PubMedID: 17008931

Title : Heterogeneity and selective targeting of neuronal nicotinic acetylcholine receptor (nAChR) subtypes expressed on retinal afferents of the superior colliculus and lateral geniculate nucleus: identification of a new native nAChR subtype alpha3beta2(alpha5 or beta3) enriched in retinocollicular afferents - Gotti_2005_Mol.Pharmacol_68_1162
Author(s) : Gotti C , Moretti M , Zanardi A , Gaimarri A , Champtiaux N , Changeux JP , Whiteaker P , Marks MJ , Clementi F , Zoli M
Ref : Molecular Pharmacology , 68 :1162 , 2005
Abstract :
PubMedSearch : Gotti_2005_Mol.Pharmacol_68_1162
PubMedID: 16049166

Title : A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels - Grutter_2005_C.R.Biol_328_223
Author(s) : Grutter T , Prado de Carvalho L , Virginie D , Taly A , Fischer M , Changeux JP
Ref : C R Biol , 328 :223 , 2005
Abstract :
PubMedSearch : Grutter_2005_C.R.Biol_328_223
PubMedID: 15810546

Title : Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors - Maskos_2005_Nature_436_103
Author(s) : Maskos U , Molles BE , Pons S , Besson M , Guiard BP , Guilloux JP , Evrard A , Cazala P , Cormier A , Mameli-Engvall M , Dufour N , Cloez-Tayarani I , Bemelmans AP , Mallet J , Gardier AM , David V , Faure P , Granon S , Changeux JP
Ref : Nature , 436 :103 , 2005
Abstract :
PubMedSearch : Maskos_2005_Nature_436_103
PubMedID: 16001069

Title : Allosteric mechanisms of signal transduction - Changeux_2005_Science_308_1424
Author(s) : Changeux JP , Edelstein SJ
Ref : Science , 308 :1424 , 2005
Abstract :
PubMedSearch : Changeux_2005_Science_308_1424
PubMedID: 15933191

Title : Nicotine upregulates its own receptors through enhanced intracellular maturation - Sallette_2005_Neuron_46_595
Author(s) : Sallette J , Pons S , Devillers-Thiery A , Soudant M , Prado de Carvalho L , Changeux JP , Corringer PJ
Ref : Neuron , 46 :595 , 2005
Abstract :
PubMedSearch : Sallette_2005_Neuron_46_595
PubMedID: 15944128

Title : Molecular tuning of fast gating in pentameric ligand-gated ion channels - Grutter_2005_Proc.Natl.Acad.Sci.U.S.A_102_18207
Author(s) : Grutter T , de Carvalho LP , Dufresne V , Taly A , Edelstein SJ , Changeux JP
Ref : Proc Natl Acad Sci U S A , 102 :18207 , 2005
Abstract :
PubMedSearch : Grutter_2005_Proc.Natl.Acad.Sci.U.S.A_102_18207
PubMedID: 16319224

Title : Critical role of the C-terminal segment in the maturation and export to the cell surface of the homopentameric alpha 7-5HT3A receptor - Pons_2004_Eur.J.Neurosci_20_2022
Author(s) : Pons S , Sallette J , Bourgeois JP , Taly A , Changeux JP , Devillers-Thiery A
Ref : European Journal of Neuroscience , 20 :2022 , 2004
Abstract :
PubMedSearch : Pons_2004_Eur.J.Neurosci_20_2022
PubMedID: 15450081

Title : Reduction of withdrawal signs after chronic nicotine exposure of alpha-calcitonin gene-related peptide knock-out mice - Salmon_2004_Neurosci.Lett_360_73
Author(s) : Salmon AM , Evrard A , Damaj MI , Changeux JP
Ref : Neuroscience Letters , 360 :73 , 2004
Abstract :
PubMedSearch : Salmon_2004_Neurosci.Lett_360_73
PubMedID: 15082182

Title : Knockout and knockin mice to investigate the role of nicotinic receptors in the central nervous system - Champtiaux_2004_Prog.Brain.Res_145_235
Author(s) : Champtiaux N , Changeux JP
Ref : Prog Brain Res , 145 :235 , 2004
Abstract :
PubMedSearch : Champtiaux_2004_Prog.Brain.Res_145_235
PubMedID: 14650919

Title : An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors - Grutter_2003_EMBO.J_22_1990
Author(s) : Grutter T , Prado de Carvalho L , Le Novere N , Corringer PJ , Edelstein SJ , Changeux JP
Ref : EMBO Journal , 22 :1990 , 2003
Abstract :
PubMedSearch : Grutter_2003_EMBO.J_22_1990
PubMedID: 12727867

Title : An in vitro study of the sub-cellular distribution of nicotinic receptors - Devillers-Thiery_2003_Biol.Cell_95_373
Author(s) : Devillers-Thiery A , Bourgeois JP , Pons S , Le Sourd A , Pucci B , Changeux JP
Ref : Biology of the cell , 95 :373 , 2003
Abstract :
PubMedSearch : Devillers-Thiery_2003_Biol.Cell_95_373
PubMedID: 14519554

Title : Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice - Champtiaux_2003_J.Neurosci_23_7820
Author(s) : Champtiaux N , Gotti C , Cordero-Erausquin M , David DJ , Przybylski C , Lena C , Clementi F , Moretti M , Rossi FM , Le Novere N , McIntosh JM , Gardier AM , Changeux JP
Ref : Journal of Neuroscience , 23 :7820 , 2003
Abstract :
PubMedSearch : Champtiaux_2003_J.Neurosci_23_7820
PubMedID: 12944511

Title : Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts - Marchand_2002_J.Neurosci_22_8891
Author(s) : Marchand S , Devillers-Thiery A , Pons S , Changeux JP , Cartaud J
Ref : Journal of Neuroscience , 22 :8891 , 2002
Abstract :
PubMedSearch : Marchand_2002_J.Neurosci_22_8891
PubMedID: 12388596

Title : Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor - Fruchart-Gaillard_2002_Proc.Natl.Acad.Sci.U.S.A_99_3216
Author(s) : Fruchart-Gaillard C , Gilquin B , Antil-Delbeke S , Le Novere N , Tamiya T , Corringer PJ , Changeux JP , Menez A , Servent D
Ref : Proc Natl Acad Sci U S A , 99 :3216 , 2002
Abstract :
PubMedSearch : Fruchart-Gaillard_2002_Proc.Natl.Acad.Sci.U.S.A_99_3216
PubMedID: 11867717

Title : The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences - Le_2002_J.Neurobiol_53_447
Author(s) : Le Novere N , Corringer PJ , Changeux JP
Ref : Journal of Neurobiology , 53 :447 , 2002
Abstract :
PubMedSearch : Le_2002_J.Neurobiol_53_447
PubMedID: 12436412

Title : Acute and long-term changes in the mesolimbic dopamine pathway after systemic or local single nicotine injections - Ferrari_2002_Eur.J.Neurosci_15_1810
Author(s) : Ferrari R , Le Novere N , Picciotto MR , Changeux JP , Zoli M
Ref : European Journal of Neuroscience , 15 :1810 , 2002
Abstract :
PubMedSearch : Ferrari_2002_Eur.J.Neurosci_15_1810
PubMedID: 12081661

Title : The role of nicotinic receptor beta-2 subunits in nicotine discrimination and conditioned taste aversion - Shoaib_2002_Neuropharmacol_42_530
Author(s) : Shoaib M , Gommans J , Morley A , Stolerman IP , Grailhe R , Changeux JP
Ref : Neuropharmacology , 42 :530 , 2002
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PubMedID: 11955523

Title : Desensitization of neuronal nicotinic acetylcholine receptors conferred by N-terminal segments of the beta 2 subunit - Bohler_2001_Biochemistry_40_2066
Author(s) : Bohler S , Gay S , Bertrand S , Corringer PJ , Edelstein SJ , Changeux JP , Bertrand D
Ref : Biochemistry , 40 :2066 , 2001
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PubMedID: 11329274

Title : Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: a function mediated by a different nAChR than dopamine release from striatum - Grady_2001_J.Neurochem_76_258
Author(s) : Grady SR , Meinerz NM , Cao J , Reynolds AM , Picciotto MR , Changeux JP , McIntosh JM , Marks MJ , Collins AC
Ref : Journal of Neurochemistry , 76 :258 , 2001
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PubMedSearch : Grady_2001_J.Neurochem_76_258
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Title : Nicotine receptor inactivation decreases sensitivity to cocaine - Zachariou_2001_Neuropsychopharmacology_24_576
Author(s) : Zachariou V , Caldarone BJ , Weathers-Lowin A , George TP , Elsworth JD , Roth RH , Changeux JP , Picciotto MR
Ref : Neuropsychopharmacology , 24 :576 , 2001
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PubMedID: 11282258

Title : Targeting transcription to the neuromuscular synapse - Schaeffer_2001_Neuron_31_15
Author(s) : Schaeffer L , de Kerchove d'Exaerde A , Changeux JP
Ref : Neuron , 31 :15 , 2001
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PubMedID: 11498047

Title : Structural differences in the two agonist binding sites of the Torpedo nicotinic acetylcholine receptor revealed by time-resolved fluorescence spectroscopy - Martinez_2000_Biochemistry_39_6979
Author(s) : Martinez KL , Corringer PJ , Edelstein SJ , Changeux JP , Merola F
Ref : Biochemistry , 39 :6979 , 2000
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PubMedSearch : Martinez_2000_Biochemistry_39_6979
PubMedID: 10841780

Title : Nicotinic-agonist stimulated (86)Rb(+) efflux and [(3)H]epibatidine binding of mice differing in beta2 genotype - Marks_2000_Neuropharmacol_39_2632
Author(s) : Marks MJ , Stitzel JA , Grady SR , Picciotto MR , Changeux JP , Collins AC
Ref : Neuropharmacology , 39 :2632 , 2000
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PubMedSearch : Marks_2000_Neuropharmacol_39_2632
PubMedID: 11044733

Title : Knockout Mice as Animal Models for Studying Nicotinic Acetylcholine Receptor Function -
Author(s) : Marubio LM , Changeux JP
Ref : Handbook of Experimental Pharmacology , 144 :525 , 2000
PubMedID:

Title : Molecular determinants by which a long chain toxin from snake venom interacts with the neuronal alpha 7-nicotinic acetylcholine receptor - Antil-Delbeke_2000_J.Biol.Chem_275_29594
Author(s) : Antil-Delbeke S , Gaillard C , Tamiya T , Corringer PJ , Changeux JP , Servent D , Menez A
Ref : Journal of Biological Chemistry , 275 :29594 , 2000
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PubMedSearch : Antil-Delbeke_2000_J.Biol.Chem_275_29594
PubMedID: 10852927

Title : Molecular characterization of the specificity of interactions of various neurotoxins on two distinct nicotinic acetylcholine receptors - Servent_2000_Eur.J.Pharmacol_393_197
Author(s) : Servent D , Antil-Delbeke S , Gaillard C , Corringer PJ , Changeux JP , Menez A
Ref : European Journal of Pharmacology , 393 :197 , 2000
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Title : How well can molecular modelling predict the crystal structure: the case of the ligand-binding domain of glutamate receptors - Paas_2000_Trends.Pharmacol.Sci_21_87
Author(s) : Paas Y , Devillers-Thiery A , Teichberg VI , Changeux JP , Eisenstein M
Ref : Trends in Pharmacological Sciences , 21 :87 , 2000
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PubMedSearch : Paas_2000_Trends.Pharmacol.Sci_21_87
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Title : Pharmacological and null mutation approaches reveal nicotinic receptor diversity - Whiteaker_2000_Eur.J.Pharmacol_393_123
Author(s) : Whiteaker P , Marks MJ , Grady SR , Lu Y , Picciotto MR , Changeux JP , Collins AC
Ref : European Journal of Pharmacology , 393 :123 , 2000
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PubMedID: 10771005

Title : Molecular basis of the charge selectivity of nicotinic acetylcholine receptor and related ligand-gated ion channels - Corringer_1999_Novartis.Found.Symp_225_215
Author(s) : Corringer PJ , Bertrand S , Galzi JL , Devillers-Thiery A , Changeux JP , Bertrand D
Ref : Novartis Found Symp , 225 :215 , 1999
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Title : Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor - Corringer_1999_Neuron_22_831
Author(s) : Corringer PJ , Bertrand S , Galzi JL , Devillers-Thiery A , Changeux JP , Bertrand D
Ref : Neuron , 22 :831 , 1999
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Title : Involvement of alpha6 nicotinic receptor subunit in nicotine-elicited locomotion, demonstrated by in vivo antisense oligonucleotide infusion - le Novere_1999_Neuroreport_10_2497
Author(s) : Le Novere N , Zoli M , Lena C , Ferrari R , Picciotto MR , Merlo-Pich E , Changeux JP
Ref : Neuroreport , 10 :2497 , 1999
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PubMedSearch : le Novere_1999_Neuroreport_10_2497
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Title : Reduced antinociception in mice lacking neuronal nicotinic receptor subunits - Marubio_1999_Nature_398_805
Author(s) : Marubio LM , del Mar Arroyo-Jimenez M , Cordero-Erausquin M , Lena C , Le Novere N , de Kerchove d'Exaerde A , Huchet M , Damaj MI , Changeux JP
Ref : Nature , 398 :805 , 1999
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PubMedSearch : Marubio_1999_Nature_398_805
PubMedID: 10235262

Title : Use of knock-out mice to determine the molecular basis for the actions of nicotine - Picciotto_1999_Nicotine.Tob.Res_1 Suppl 2_S121
Author(s) : Picciotto MR , Zoli M , Changeux JP
Ref : Nicotine Tob Res , 1 Suppl 2 :S121 , 1999
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PubMedSearch : Picciotto_1999_Nicotine.Tob.Res_1 Suppl 2_S121
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Title : International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits -
Author(s) : Lukas RJ , Changeux JP , Le Novere N , Albuquerque EX , Balfour DJ , Berg DK , Bertrand D , Chiappinelli VA , Clarke PB , Collins AC , Dani JA , Grady SR , Kellar KJ , Lindstrom JM , Marks MJ , Quik M , Taylor P , Wonnacott S
Ref : Pharmacol Rev , 51 :397 , 1999
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Title : Modulation of morphine analgesia in alphaCGRP mutant mice - Salmon_1999_Neuroreport_10_849
Author(s) : Salmon AM , Damaj MI , Sekine S , Picciotto MR , Marubio L , Changeux JP
Ref : Neuroreport , 10 :849 , 1999
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Title : Two pharmacologically distinct components of nicotinic receptor-mediated rubidium efflux in mouse brain require the beta2 subunit - Marks_1999_J.Pharmacol.Exp.Ther_289_1090
Author(s) : Marks MJ , Whiteaker P , Calcaterra J , Stitzel JA , Bullock AE , Grady SR , Picciotto MR , Changeux JP , Collins AC
Ref : Journal of Pharmacology & Experimental Therapeutics , 289 :1090 , 1999
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PubMedSearch : Marks_1999_J.Pharmacol.Exp.Ther_289_1090
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Title : Assessment of nicotinic acetylcholine receptor subunit contributions to nicotine self-administration in mutant mice -
Author(s) : Epping-Jordan MP , Picciotto MR , Changeux JP , Pich EM
Ref : Psychopharmacology (Berl) , 147 :25 , 1999
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Title : Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors - Zoli_1999_EMBO.J_18_1235
Author(s) : Zoli M , Picciotto MR , Ferrari R , Cocchi D , Changeux JP
Ref : EMBO Journal , 18 :1235 , 1999
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PubMedSearch : Zoli_1999_EMBO.J_18_1235
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Title : Analysis of developmental evolution of synapses in CGRP knock-out mice -
Author(s) : Salmon AM , Sekine S , Picciotto MR , Damaj MI , Changeux JP
Ref : Journal de Physiologie (Paris) , 92 :488 , 1998
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Title : Implication of a multisubunit Ets related transcription factor in synaptic expression of the nicotinic acetylcholine receptor -
Author(s) : Schaeffer L , de Kerchove d'Exaerde A , Duclert N , Huchet-Dymanus M , Changeux JP
Ref : Journal de Physiologie (Paris) , 92 :489 , 1998
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Title : An antibody specific for the neuronal nicotinic acetylcholine receptor alpha 4 subunit: High levels of expression in monoaminergic neurons -
Author(s) : Arroyo-Jimenez MM , Bourgeois JP , Le Sourd AM , Fairen A , Changeux JP
Ref : Journal de Physiologie (Paris) , 92 :405 , 1998
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Title : Allosteric receptors after 30 years -
Author(s) : Changeux JP , Edelstein SJ
Ref : Neuron , 21 :959 , 1998
PubMedID: 9856454

Title : Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine - Picciotto_1998_Nature_391_173
Author(s) : Picciotto MR , Zoli M , Rimondini R , Lena C , Marubio LM , Pich EM , Fuxe K , Changeux JP
Ref : Nature , 391 :173 , 1998
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Title : Regulation of desensitization by beta subunit in neuronal nAchR -
Author(s) : Bohler S , Corringer PJ , Changeux JP , Bertrand S , Bertrand D , Edelstein SJ
Ref : Journal de Physiologie (Paris) , 92 :414 , 1998
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Title : Critical elements determining diversity in agonist binding and desensitization of neuronal nicotinic acetylcholine receptors - Corringer_1998_J.Neurosci_18_648
Author(s) : Corringer PJ , Bertrand S , Bohler S , Edelstein SJ , Changeux JP , Bertrand D
Ref : Journal of Neuroscience , 18 :648 , 1998
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Title : Characterization of mice lacking the nicotinic receptoralpha4 subunit -
Author(s) : Cordero-Erausquin LM , Marubio LM , Arroyo-Jimenez MM , Le Novere N , Huchet M , Lena C , Changeux JP
Ref : Journal de Physiologie (Paris) , 92 :423 , 1998
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Title : Critical elements determining diversity in agonist binding and desensitization of neuronal nAChR -
Author(s) : Corringer PJ , Bertrand S , Bohler S , Edelstein SJ , Bertrand D , Changeux JP
Ref : Journal de Physiologie (Paris) , 92 :424 , 1998
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Title : Allosteric transitions of the acetylcholine receptor -
Author(s) : Edelstein SJ , Changeux JP
Ref : Advances in Protein Chemistry , 51 :121 , 1998
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Title : Identification of four classes of brain nicotinic receptors using beta2 mutant mice - Zoli_1998_J.Neurosci_18_4461
Author(s) : Zoli M , Lena C , Picciotto MR , Changeux JP
Ref : Journal of Neuroscience , 18 :4461 , 1998
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PubMedSearch : Zoli_1998_J.Neurosci_18_4461
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Title : Nonmyogenic factors bind nicotinic acetylcholine receptor promoter elements required for response to denervation - Bessereau_1998_J.Biol.Chem_273_12786
Author(s) : Bessereau JL , Laudenbach V , Le Poupon C , Changeux JP
Ref : Journal of Biological Chemistry , 273 :12786 , 1998
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Title : Predicted secondary structure of a nicotinic acetylcholine receptor subunit. Incorporation of predicted solvent accessibility and experimental data into a two dimensional representation -
Author(s) : Le Novere N , Corringer PJ , Changeux JP
Ref : Journal de Physiologie (Paris) , 92 :458 , 1998
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Title : Structural discrimination between the two agonist binding sites of the Torpedo nicotinic acetylcholine receptor using time resolved fluorescence -
Author(s) : Martinez K , Corringer PJ , Merola F , Changeux JP
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Title : Artificial toxins to explore new receptors? -
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Ref : Journal de Physiologie (Paris) , 92 :468 , 1998
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Title : Involvement of protein kinases and protein phosphatases in the regulation of acetylcholine receptor gene expression -
Author(s) : Nghiem HO , Changeux JP
Ref : Journal de Physiologie (Paris) , 92 :475 , 1998
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Title : Differential susceptibility of young and old rat neuromuscular junctions to antibody-mediated AChR degradation in experimental autoimmune myasthenia gravis -
Author(s) : Hoedemaekers A , Bessereau JL , Graus Y , Guyon T , Changeux JP , Berrih-Aknin S , Van Breda Vriesman P , de Baets M
Ref : Annals of the New York Academy of Sciences , 841 :550 , 1998
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Title : Role of the target organ in determining susceptibility to experimental autoimmune myasthenia gravis - Hoedemaekers_1998_J.Neuroimmunol_89_131
Author(s) : Hoedemaekers A , Bessereau JL , Graus Y , Guyon T , Changeux JP , Berrih-Aknin S , Van Breda Vriesman P , De Baets MH
Ref : Journal of Neuroimmunology , 89 :131 , 1998
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Title : Paradoxical allosteric effects of competitive inhibitors on neuronal alpha7 nicotinic receptor mutants - Bertrand_1997_Neuroreport_8_3591
Author(s) : Bertrand S , Devillers-Thiery A , Palma E , Buisson B , Edelstein SJ , Corringer PJ , Changeux JP , Bertrand D
Ref : Neuroreport , 8 :3591 , 1997
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Title : Contribution of nicotinic acetylcholine receptors containing the beta 2-subunit to the behavioural effects of nicotine -
Author(s) : Picciotto MR , Zoli M , Zachariou V , Changeux JP
Ref : Biochemical Society Transactions , 25 :824 , 1997
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Title : Myasthenic nicotinic receptor mutant interpreted in terms of the allosteric model - Edelstein_1997_C.R.Acad.Sci.III_320_953
Author(s) : Edelstein SJ , Schaad O , Changeux JP
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Title : Single binding versus single channel recordings: a new approach to study ionotropic receptors - Edelstein_1997_Biochemistry_36_13755
Author(s) : Edelstein SJ , Schaad O , Changeux JP
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Title : Enhanced hemicholinium binding and attenuated dendrite branching in cognitively impaired acetylcholinesterase-transgenic mice - Beeri_1997_J.Neurochem_69_2441
Author(s) : Beeri R , Le Novere N , Mervis R , Huberman T , Grauer E , Changeux JP , Soreq H
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Title : Allosteric proteins after thirty years: the binding and state functions of the neuronal alpha 7 nicotinic acetylcholine receptors - Edelstein_1996_Experientia_52_1083
Author(s) : Edelstein SJ , Changeux JP
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Title : A kinetic mechanism for nicotinic acetylcholine receptors based on multiple allosteric transitions - Edelstein_1996_Biol.Cybern_75_361
Author(s) : Edelstein SJ , Schaad O , Henry E , Bertrand D , Changeux JP
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Title : Nicotinic receptors and brain plasticity -
Author(s) : Changeux JP , Bessis A , Bourgeois JP , Corringer PJ , Devillers-Thiery A , Eisele JL , Kerszberg M , Lena C , Le Novere N , Picciotto MR , Zoli M
Ref : Cold Spring Harbor Symposium on Quantitative Biology , 61 :343 , 1996
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Title : Identification of an extracellular motif involved in the binding of guanine nucleotides by a glutamate receptor - Paas_1996_EMBO.J_15_1548
Author(s) : Paas Y , Devillers-Thiery A , Changeux JP , Medevielle F , Teichberg VI
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Title : Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain - Picciotto_1995_Nature_374_65
Author(s) : Picciotto MR , Zoli M , Lena C , Bessis A , Lallemand Y , Le Novere N , Vincent P , Pich EM , Brulet P , Changeux JP
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Title : ErbB3 and ErbB2\/neu mediate the effect of heregulin on acetylcholine receptor gene expression in muscle: differential expression at the endplate - Altiok_1995_EMBO.J_14_4258
Author(s) : Altiok N , Bessereau JL , Changeux JP
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Title : Developmental regulation of acetylcholinesterase transcripts in the mouse diaphragm: alternative splicing and focalization - Legay_1995_Eur.J.Neurosci_7_1803
Author(s) : Legay C , Huchet M , Massoulie J , Changeux JP
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Title : Developmental Regulation of Acetylcholinesterase mRNA in the Mouse Diaphragm -
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Title : In vivo and in vitro analysis of electrical activity-dependent expression of muscle acetylcholine receptor genes using adenovirus - Bessereau_1994_Proc.Natl.Acad.Sci.U.S.A_91_1304
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Title : Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor - Bertrand_1993_Proc.Natl.Acad.Sci.U.S.A_90_6971
Author(s) : Bertrand D , Galzi JL , Devillers-Thiery A , Bertrand S , Changeux JP
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Title : Stratification of the channel domain in neurotransmitter receptors - Bertrand_1993_Curr.Opin.Cell.Biol_5_688
Author(s) : Bertrand D , Galzi JL , Devillers-Thiery A , Bertrand S , Changeux JP
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Title : Negative regulatory elements upstream of a novel exon of the neuronal nicotinic acetylcholine receptor alpha 2 subunit gene - Bessis_1993_Nucleic.Acids.Res_21_2185
Author(s) : Bessis A , Savatier N , Devillers-Thiery A , Bejanin S , Changeux JP
Ref : Nucleic Acids Research , 21 :2185 , 1993
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Title : Chicken neuronal acetylcholine receptor alpha 2-subunit gene exhibits neuron-specific expression in the brain and spinal cord of transgenic mice - Daubas_1993_Proc.Natl.Acad.Sci.U.S.A_90_2237
Author(s) : Daubas P , Salmon AM , Zoli M , Geoffroy B , Devillers-Thiery A , Bessis A , Medevielle F , Changeux JP
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Title : Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels -
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Title : Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities - Eisele_1993_Nature_366_479
Author(s) : Eisele JL , Bertrand S , Galzi JL , Devillers-Thiery A , Changeux JP , Bertrand D
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Title : Muscle-specific expression of the acetylcholine receptor alpha-subunit gene requires both positive and negative interactions between myogenic factors, Sp1 and GBF factors - Bessereau_1993_EMBO.J_12_443
Author(s) : Bessereau JL , Mendelzon D , LePoupon C , Fiszman M , Changeux JP , Piette J
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Title : Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain - Bertrand_1992_Proc.Natl.Acad.Sci.U.S.A_89_1261
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Title : Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic - Galzi_1992_Nature_359_500
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Title : Stratified organization of the nicotinic acetylcholine receptor channel - Devillers-Thiery_1992_Neuroreport_3_1001
Author(s) : Devillers-Thiery A , Galzi JL , Bertrand S , Changeux JP , Bertrand D
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Title : New mutants to explore nicotinic receptor functions -
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Title : The acetylcholine receptor: a model of an allosteric membrane protein mediating intercellular communication - Changeux_1992_Ciba.Found.Symp_164_66
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Title : The functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis -
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Title : An acetylcholine receptor alpha-subunit promoter conferring preferential synaptic expression in muscle of transgenic mice - Klarsfeld_1991_EMBO.J_10_625
Author(s) : Klarsfeld A , Bessereau JL , Salmon AM , Triller A , Babinet C , Changeux JP
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Title : Functional significance of aromatic amino acids from three peptide loops of the alpha 7 neuronal nicotinic receptor site investigated by site-directed mutagenesis - Galzi_1991_FEBS.Lett_294_198
Author(s) : Galzi JL , Bertrand D , Devillers-Thiery A , Revah F , Bertrand S , Changeux JP
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Title : Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor - Revah_1991_Nature_353_846
Author(s) : Revah F , Bertrand D , Galzi JL , Devillers-Thiery A , Mulle C , Hussy N , Bertrand S , Ballivet M , Changeux JP
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Title : Two adjacent MyoD1-binding sites regulate expression of the acetylcholine receptor alpha-subunit gene - Piette_1990_Nature_345_353
Author(s) : Piette J , Bessereau JL , Huchet M , Changeux JP
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Title : Chromosomal localization of the mouse genes coding for alpha 2, alpha 3, alpha 4 and beta 2 subunits of neuronal nicotinic acetylcholine receptor - Bessis_1990_FEBS.Lett_264_48
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Title : Differential expression of the neuronal acetylcholine receptor alpha 2 subunit gene during chick brain development - Daubas_1990_Neuron_5_49
Author(s) : Daubas P , Devillers-Thiery A , Geoffroy B , Martinez S , Bessis A , Changeux JP
Ref : Neuron , 5 :49 , 1990
Abstract :
PubMedSearch : Daubas_1990_Neuron_5_49
PubMedID: 2369520

Title : Compartmentalization of acetylcholine receptor gene expression during development of the neuromuscular junction -
Author(s) : Changeux JP , Babinet C , Bessereau JL , Bessis A , Cartaud A , Cartaud J , Daubas P , Devillers-Thiery A , Duclert A , Hill JA , et al.
Ref : Cold Spring Harbor Symposium on Quantitative Biology , 55 :381 , 1990
PubMedID: 2132828

Title : The acetylcholine receptor: functional architecture and regulation -
Author(s) : Changeux JP , Benoit P , Bessis A , Cartaud J , Devillers-Thiery A , Fontaine B , Galzi JL , Klarsfeld A , Laufer R , Mulle C , et al.
Ref : Adv Second Messenger Phosphoprotein Res , 24 :15 , 1990
PubMedID: 1698404

Title : Regulation of acetylcholine receptor gene expression by neural factors and electrical activity during motor endplate formation -
Author(s) : Changeux JP , Benoit P , Bessis A , Cartaud J , Devillers-Thiery A , Fontaine B , Galzi JL , Klarsfeld A , Laufer R , Mulle C , et al.
Ref : Biochemical Society Symposium , 56 :9 , 1990
PubMedID: 2256962

Title : Denervation of mouse skeletal muscle differentially affects the expression of the jun and fos proto-oncogenes - Bessereau_1990_New.Biol_2_375
Author(s) : Bessereau JL , Fontaine B , Changeux JP
Ref : New Biol , 2 :375 , 1990
Abstract :
PubMedSearch : Bessereau_1990_New.Biol_2_375
PubMedID: 2126956

Title : Acetylcholine receptor expression in primary cultures of embryonic chick myotubes--II. Comparison between the effects of spinal cord cells and calcitonin gene-related peptide - Kirilovsky_1989_Neurosci_32_289
Author(s) : Kirilovsky J , Duclert A , Fontaine B , Devillers-Thiery A , Osterlund M , Changeux JP
Ref : Neuroscience , 32 :289 , 1989
Abstract :
PubMedSearch : Kirilovsky_1989_Neurosci_32_289
PubMedID: 2586756

Title : Regulation of muscle AChR alpha subunit gene expression by electrical activity: involvement of protein kinase C and Ca2+ - Klarsfeld_1989_Neuron_2_1229
Author(s) : Klarsfeld A , Laufer R , Fontaine B , Devillers-Thiery A , Dubreuil C , Changeux JP
Ref : Neuron , 2 :1229 , 1989
Abstract :
PubMedSearch : Klarsfeld_1989_Neuron_2_1229
PubMedID: 2516449

Title : Asynchronous assembly of the acetylcholine receptor and of the 43-kD nu1 protein in the postsynaptic membrane of developing Torpedo marmorata electrocyte - Kordeli_1989_J.Cell.Biol_108_127
Author(s) : Kordeli E , Cartaud J , Nghiem HO , Devillers-Thiery A , Changeux JP
Ref : Journal of Cell Biology , 108 :127 , 1989
Abstract :
PubMedSearch : Kordeli_1989_J.Cell.Biol_108_127
PubMedID: 2642909

Title : [Possible trophic role on the neuromuscular junction of a neuropeptide co-existing with acetylcholine in motor neurons of the spinal cord] - Fontaine_1989_Rev.Neurol.(Paris)_145_194
Author(s) : Fontaine B , Klarsfeld A , Laufer R , Hokfelt T , Changeux JP
Ref : Rev Neurol (Paris) , 145 :194 , 1989
Abstract :
PubMedSearch : Fontaine_1989_Rev.Neurol.(Paris)_145_194
PubMedID: 2546240

Title : Acetylcholine receptor expression in primary cultures of embryonic chick myotubes--I. Discoordinate regulation of alpha-, gamma- and delta-subunit gene expression by calcitonin gene-related peptide and by muscle electrical activity - Osterlund_1989_Neurosci_32_279
Author(s) : Osterlund M , Fontaine B , Devillers-Thiery A , Geoffroy B , Changeux JP
Ref : Neuroscience , 32 :279 , 1989
Abstract :
PubMedSearch : Osterlund_1989_Neurosci_32_279
PubMedID: 2586755

Title : Calcitonin gene-related peptide, a peptide present in spinal cord motoneurons, increases the number of acetylcholine receptors in primary cultures of chick embryo myotubes - Fontaine_1986_Neurosci.Lett_71_59
Author(s) : Fontaine B , Klarsfeld A , Hokfelt T , Changeux JP
Ref : Neuroscience Letters , 71 :59 , 1986
Abstract :
PubMedSearch : Fontaine_1986_Neurosci.Lett_71_59
PubMedID: 3491345

Title : Chromosomal localization of muscle nicotinic acetylcholine receptor genes in the mouse - Heidmann_1986_Science_234_866
Author(s) : Heidmann O , Buonanno A , Geoffroy B , Robert B , Guenet JL , Merlie JP , Changeux JP
Ref : Science , 234 :866 , 1986
Abstract :
PubMedSearch : Heidmann_1986_Science_234_866
PubMedID: 3022377

Title : Transmembrane topology of acetylcholine receptor subunits probed with photoreactive phospholipids - Giraudat_1985_Biochemistry_24_3121
Author(s) : Giraudat J , Montecucco C , Bisson R , Changeux JP
Ref : Biochemistry , 24 :3121 , 1985
Abstract :
PubMedSearch : Giraudat_1985_Biochemistry_24_3121
PubMedID: 4027235

Title : Molecular genetics of Torpedo marmorata acetylcholine receptor -
Author(s) : Devillers-Thiery A , Giraudat J , Bentaboulet M , Klarsfeld A , Changeux JP
Ref : Advances in Experimental Medicine & Biology , 181 :17 , 1984
PubMedID: 6549423

Title : A single gene codes for the nicotinic acetylcholine receptor alpha-subunit in Torpedo marmorata: structural and developmental implications - Klarsfeld_1984_EMBO.J_3_35
Author(s) : Klarsfeld A , Devillers-Thiery A , Giraudat J , Changeux JP
Ref : EMBO Journal , 3 :35 , 1984
Abstract :
PubMedSearch : Klarsfeld_1984_EMBO.J_3_35
PubMedID: 6323168

Title : Lipid-dependent recovery of alpha-bungarotoxin and monoclonal antibody binding to the purified alpha-subunit from Torpedo marmorata acetylcholine receptor. Enhancement by noncompetitive channel blockers - Tzartos_1984_J.Biol.Chem_259_11512
Author(s) : Tzartos SJ , Changeux JP
Ref : Journal of Biological Chemistry , 259 :11512 , 1984
Abstract :
PubMedSearch : Tzartos_1984_J.Biol.Chem_259_11512
PubMedID: 6088547

Title : Complete nucleotide sequence of Torpedo marmorata mRNA coding for the 43,000-dalton nu 2 protein: muscle-specific creatine kinase - Giraudat_1984_Proc.Natl.Acad.Sci.U.S.A_81_7313
Author(s) : Giraudat J , Devillers-Thiery A , Perriard JC , Changeux JP
Ref : Proc Natl Acad Sci U S A , 81 :7313 , 1984
Abstract :
PubMedSearch : Giraudat_1984_Proc.Natl.Acad.Sci.U.S.A_81_7313
PubMedID: 6095285

Title : Acetylcholine receptor: an allosteric protein - Changeux_1984_Science_225_1335
Author(s) : Changeux JP , Devillers-Thiery A , Chemouilli P
Ref : Science , 225 :1335 , 1984
Abstract :
PubMedSearch : Changeux_1984_Science_225_1335
PubMedID: 6382611

Title : Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain - Devillers-Thiery_1983_Proc.Natl.Acad.Sci.U.S.A_80_2067
Author(s) : Devillers-Thiery A , Giraudat J , Bentaboulet M , Changeux JP
Ref : Proc Natl Acad Sci U S A , 80 :2067 , 1983
Abstract :
PubMedSearch : Devillers-Thiery_1983_Proc.Natl.Acad.Sci.U.S.A_80_2067
PubMedID: 6572962

Title : Allosteric properties of the acetylcholine receptor protein from Torpedo marmorata -
Author(s) : Changeux JP , Bon F , Cartaud J , Devillers-Thiery A , Giraudat J , Heidmann T , Holton B , Nghiem HO , Popot JL , Van Rapenbusch R , et al.
Ref : Cold Spring Harbor Symposium on Quantitative Biology , 48 Pt 1 :35 , 1983
PubMedID: 6327163

Title : Rapid kinetics of agonist binding and permeability response analyzed in parallel on acetylcholine receptor rich membranes from Torpedo marmorata - Heidmann_1983_Biochemistry_22_5452
Author(s) : Heidmann T , Bernhardt J , Neumann E , Changeux JP
Ref : Biochemistry , 22 :5452 , 1983
Abstract :
PubMedSearch : Heidmann_1983_Biochemistry_22_5452
PubMedID: 6652072

Title : Identification of a cDNA clone coding for the acetylcholine binding subunit of Torpedo marmorata acetylcholine receptor - Giraudat_1982_EMBO.J_1_713
Author(s) : Giraudat J , Devillers-Thiery A , Auffray C , Rougeon F , Changeux JP
Ref : EMBO Journal , 1 :713 , 1982
Abstract :
PubMedSearch : Giraudat_1982_EMBO.J_1_713
PubMedID: 6897919

Title : [Effects of chronic medullary stimulation on the total number of sites of acetylcholinesterase activity of the posterior latissimus dorsi muscle of chick embryo]. [French] - Toutant_1981_C.R.Acad.Sci.III_292_771
Author(s) : Toutant M , Toutant JP , Renaud D , Le Douarin GH , Changeux JP
Ref : Comptes Rendus de l Academie des Sciences , 292 :771 , 1981
Abstract :
PubMedSearch : Toutant_1981_C.R.Acad.Sci.III_292_771
PubMedID: 6788396

Title : Chronic stimulation of the spinal cord in developing chick embryo causes the differentiation of multiple clusters of acetylcholine receptor in the posterior latissimus dorsi muscle -
Author(s) : Toutant M , Bourgeois JP , Toutant JP , Renaud D , Le Douarin GH , Changeux JP
Ref : Developmental Biology , 76 :384 , 1980
PubMedID: 7390009

Title : The amino-terminal sequence of the 40,000 molecular weight subunit of the acetylcholine receptor protein from Torpedo marmorata -
Author(s) : Devillers-Thiery A , Changeux JP , Paroutaud P , Strosberg AD
Ref : FEBS Letters , 104 :99 , 1979
PubMedID: 477982

Title : Immunological characterisation of the cholinergic receptor protein from Electrophorus electricus -
Author(s) : Sugiyama H , Benda P , Meunier JC , Changeux JP
Ref : FEBS Letters , 35 :124 , 1973
PubMedID: 4201666

Title : Effects of a snake alpha-neurotoxin on the development of innervated skeletal muscles in chick embryo - Giacobini_1973_Proc.Natl.Acad.Sci.U.S.A_70_1708
Author(s) : Giacobini G , Filogamo G , Weber M , Boquet P , Changeux JP
Ref : Proc Natl Acad Sci U S A , 70 :1708 , 1973
Abstract :
PubMedSearch : Giacobini_1973_Proc.Natl.Acad.Sci.U.S.A_70_1708
PubMedID: 4515929

Title : In Vitro excitation of purified membrane fragments by cholinergic agonists : I. Pharmalogical properties of the excitable membrane fragments - Kasai_1971_J.Membr.Biol_6_1
Author(s) : Kasai M , Changeux JP
Ref : J Membr Biol , 6 :1 , 1971
Abstract :
PubMedSearch : Kasai_1971_J.Membr.Biol_6_1
PubMedID: 24173287

Title : In vitro excitation of purified membrane fragments by cholinergic agonists. III. Comparison of the dose response curves to decamethonium with the corresponding binding curves of decamethonium to the cholinergic receptor - Kasai_1971_J.Membr.Biol_6_58
Author(s) : Kasai M , Changeux JP
Ref : J Membr Biol , 6 :58 , 1971
Abstract :
PubMedSearch : Kasai_1971_J.Membr.Biol_6_58
PubMedID: 24173289

Title : In vitro excitation of purified membrane fragments by cholinergic agonists : IV. Ultrastructure, at high resolution, of the AcChE-Rich and ATPase-rich microsacs - Cartaud_1971_J.Membr.Biol_6_81
Author(s) : Cartaud J , Benedetti EL , Kasai M , Changeux JP
Ref : J Membr Biol , 6 :81 , 1971
Abstract :
PubMedSearch : Cartaud_1971_J.Membr.Biol_6_81
PubMedID: 24173290

Title : Use of a snake venom toxin to characterize the cholinergic receptor protein - Changeux_1970_Proc.Natl.Acad.Sci.U.S.A_67_1241
Author(s) : Changeux JP , Kasai M , Lee CY
Ref : Proc Natl Acad Sci U S A , 67 :1241 , 1970
Abstract :
PubMedSearch : Changeux_1970_Proc.Natl.Acad.Sci.U.S.A_67_1241
PubMedID: 5274453

Title : On the association of tyrocidine with acetylcholinesterase - Changeux_1969_Proc.Natl.Acad.Sci.U.S.A_62_986
Author(s) : Changeux JP , Ryter A , Leuzinger W , Barrand P , Podleski T
Ref : Proc Natl Acad Sci U S A , 62 :986 , 1969
Abstract :
PubMedSearch : Changeux_1969_Proc.Natl.Acad.Sci.U.S.A_62_986
PubMedID: 5257018

Title : Affinity labelling of the acetylcholine-receptor -
Author(s) : Changeux JP , Podleski TR , Wofsy L
Ref : Proceedings of the National Academy of Sciences of the United States of America , 58 :2063 , 1967
PubMedID: 5237500

Title : [Effects of ionic forces and curarizing agents on the acetylcholine esterase properties of the electric tissue of Torpedo marmorata] -
Author(s) : Changeux JP
Ref : Comptes Rendus Hebdomadaires des Seances de l Academie des Sciences D: Sciences Naturelles , 262 :937 , 1966
PubMedID: 4956272

Title : Responses of acetylcholinesterase from Torpedo marmorata to salts and curarizing drugs -
Author(s) : Changeux JP
Ref : Molecular Pharmacology , 2 :369 , 1966
PubMedID: 5970686

Title : Allosteric proteins and cellular control systems -
Author(s) : Monod J , Changeux JP , Jacob F
Ref : Journal of Molecular Biology , 6 :306 , 1963
PubMedID: