| Title : Enzymatic removal of carboxyl protecting groups. III. Fast removal of allyl and chloroethyl esters by Bacillus subtilis esterase (BS2) - Fotakopoulou_2007_J.Org.Chem_72_782 |
| Author(s) : Fotakopoulou I , Barbayianni E , Constantinou-Kokotou V , Bornscheuer UT , Kokotos G |
| Ref : J Org Chem , 72 :782 , 2007 |
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Abstract :
An esterase from Bacillus subtilis (BS2) allows the fast and selective removal of allyl, 2-chloroethyl, and 2,2,2-chloroethyl esters under mild conditions in high yields. In addition, BS2 easily hydrolyzes phenacyl esters, while the hydrolysis of sterically hindered diphenylmethyl esters is slow, requiring longer reaction time and higher enzyme/substrate ratio. |
| PubMedSearch : Fotakopoulou_2007_J.Org.Chem_72_782 |
| PubMedID: 17253795 |
Fotakopoulou I, Barbayianni E, Constantinou-Kokotou V, Bornscheuer UT, Kokotos G (2007)
Enzymatic removal of carboxyl protecting groups. III. Fast removal of allyl and chloroethyl esters by Bacillus subtilis esterase (BS2)
J Org Chem
72 :782
Fotakopoulou I, Barbayianni E, Constantinou-Kokotou V, Bornscheuer UT, Kokotos G (2007)
J Org Chem
72 :782