| Title : Fluorescent method for evaluation of cholinesterase inhibitors - Gainullina_2006_Bull.Exp.Biol.Med_142_751 |
| Author(s) : Gainullina ET , Kondratyev KV , Ryzhikov SB , Taranchenko VF |
| Ref : Bulletin of Experimental Biology & Medicine , 142 :751 , 2006 |
|
Abstract :
The sensitivity of detection of anticholinesterase compounds (e.g. tacrine) by the biochemical method significantly increased when fluorogenic compound N-(4-(7-diethylamino-4-methylcoumarine-3-yl)phenyl)maleimide was used instead of Ellman's reagent. A kinetic fluorescent method for evaluating cholinesterase inhibitors is proposed. |
| PubMedSearch : Gainullina_2006_Bull.Exp.Biol.Med_142_751 |
| PubMedID: 17603688 |
| Substrate | Coumarinylphenylmaleimide |
Gainullina ET, Kondratyev KV, Ryzhikov SB, Taranchenko VF (2006)
Fluorescent method for evaluation of cholinesterase inhibitors
Bulletin of Experimental Biology & Medicine
142 :751
Gainullina ET, Kondratyev KV, Ryzhikov SB, Taranchenko VF (2006)
Bulletin of Experimental Biology & Medicine
142 :751