| Title : In vitro studies on the reactivation by oximes of phosphylated acetylcholinesterase--I. On the reactions of P2S with various organophosphates and the properties of the resultant phosphylated oximes - Harvey_1986_Biochem.Pharmacol_35_737 |
| Author(s) : Harvey B , Scott RP , Sellers DJ , Watts P |
| Ref : Biochemical Pharmacology , 35 :737 , 1986 |
|
Abstract :
The rates of formation and decomposition of a series of phosphylated oximes derived from P2S (2-hydroxy-iminomethyl-1-methylpyridinium methane-sulphonate) have been measured. The rates of inhibition of AChE by these phosphylated oximes and the parent (and related) organophosphates have also been measured. Possession of these rate data now permits a detailed analysis of the reactivation of phosphylated AChE by P2S to be made (see following paper). |
| PubMedSearch : Harvey_1986_Biochem.Pharmacol_35_737 |
| PubMedID: 3954783 |
| Reactivator | P2s~contrathion |
Harvey B, Scott RP, Sellers DJ, Watts P (1986)
In vitro studies on the reactivation by oximes of phosphylated acetylcholinesterase--I. On the reactions of P2S with various organophosphates and the properties of the resultant phosphylated oximes
Biochemical Pharmacology
35 :737
Harvey B, Scott RP, Sellers DJ, Watts P (1986)
Biochemical Pharmacology
35 :737