Title : Nonenzymatic all-solid-state coated wire electrode for acetylcholine determination in vitro - He_2016_Biosens.Bioelectron_85_679 |
Author(s) : He C , Wang Z , Wang Y , Hu R , Li G |
Ref : Biosensors & Bioelectronics , 85 :679 , 2016 |
Abstract : A nonenzymatic all-solid-state coated wire acetylcholine electrode was investigated. Poly(3,4-ethylenedioxythiophene) doped with poly(styrenesulfonate) (PEDOT/PSS) as conducting polymer was coated on one end of a gold wire (0.5mm in diameter). The acetylcholine selective membrane containing heptakis(2,3,6-tri-Omicron-methyl)-beta-cyclodextrin as an ionophore covered the conducting polymer layer. The electrode could work stably in a pH range of 6.5-8.5 and a temperature range of 15-40 degrees C. It covered an acetylcholine concentration range of 10(-5)-10(-1)M with a slope of 54.04+/-1.70mV/decade, while detection limit was 5.69+/-1.06microM. The selectivity, dynamic response, reproducibility and stability were evaluated. The electrode could work properly in the rat brain homogenate to detect different concentrations of acetylcholine. |
ESTHER : He_2016_Biosens.Bioelectron_85_679 |
PubMedSearch : He_2016_Biosens.Bioelectron_85_679 |
PubMedID: 27254787 |
He C, Wang Z, Wang Y, Hu R, Li G (2016)
Nonenzymatic all-solid-state coated wire electrode for acetylcholine determination in vitro
Biosensors & Bioelectronics
85 :679
He C, Wang Z, Wang Y, Hu R, Li G (2016)
Biosensors & Bioelectronics
85 :679