| Title : C-terminal amidation of calcitonin by carboxypeptidase Y catalyzed transpeptidation with a photocleavable nucleophile - Henriksen_1992_Pept.Res_5_321 |
| Author(s) : Henriksen DB , Rolland M , Jakobsen MH , Buchardt O , Breddam K |
| Ref : Pept Res , 5 :321 , 1992 |
|
Abstract :
The C-terminal amidation of calcitonin represents an important technological problem. A method using a serine carboxypeptidase-catalyzed transpeptidation reaction in combination with photochemical cleavage to give the warranted peptide amide is described. The overall yield is higher than 95%. |
| PubMedSearch : Henriksen_1992_Pept.Res_5_321 |
| PubMedID: 1493358 |
| Gene_locus related to this paper: yeast-cbpy1 |
| Gene_locus | yeast-cbpy1 |
Henriksen DB, Rolland M, Jakobsen MH, Buchardt O, Breddam K (1992)
C-terminal amidation of calcitonin by carboxypeptidase Y catalyzed transpeptidation with a photocleavable nucleophile
Pept Res
5 :321
Henriksen DB, Rolland M, Jakobsen MH, Buchardt O, Breddam K (1992)
Pept Res
5 :321