Heymann_1993_Biol.Chem.Hoppe.Seyler_374_1033

Reference

Title : A note on the identity of porcine liver carboxylesterase and prolyl-beta-naphthylamidase - Heymann_1993_Biol.Chem.Hoppe.Seyler_374_1033
Author(s) : Heymann E , Peter K
Ref : Biol Chem Hoppe Seyler , 374 :1033 , 1993
Abstract :

Prolyl-beta-naphthylamidase from porcine liver is compared with the two prevalent isoenzymes of pig liver carboxylesterase by isoelectrofocusing experiments and by inhibition studies with phenyl-methyl-sulfonyl fluoride. The results suggest that prolyl-beta-naphthylamidase is identical with the amide-cleaving isoenzyme of carboxylesterase, not with the usually predominant methyl butyrate-hydrolysing isoenzyme. It is questionable whether the recently published sequence of prolyl-beta-naphthylamidase does belong to this enzyme or to the predominant carboxylesterase without amidase activity. Surprisingly, the amide-cleaving carboxylesterase isoenzymes from rat liver have almost no activity with prolyl-beta-naphthylamide.

PubMedSearch : Heymann_1993_Biol.Chem.Hoppe.Seyler_374_1033
PubMedID: 8292262
Gene_locus related to this paper: pig-EST1

Related information

Substrate Prolyl-2-naphthylamide
Gene_locus pig-EST1

Citations formats

Heymann E, Peter K (1993)
A note on the identity of porcine liver carboxylesterase and prolyl-beta-naphthylamidase
Biol Chem Hoppe Seyler 374 :1033

Heymann E, Peter K (1993)
Biol Chem Hoppe Seyler 374 :1033