Sus scrofa (Pig) carboxylesterase retinyl ester hydrolase (EC 3.1.1.-) (reh) CES1 PLE Porcine Liver esterase
There are at least 6 isoenzyme (may be different genes Q9TS80 PLE1 A5A4F5 PLE3). Isoenzymes of pig-liver esterase reveal striking differences in enantioselectivities Hummel et al. 2007<\/A>. Polyisoprenylated. methylated protein methyl esterase (PMPMEase). Pig liver esterase 5 (PLE5) (pig-a9gyw6<\/A>) is the isoenzyme crystallized (5FV4<\/A>)
Family : Carb_B_Chordata
Block : C
Position in NCBI Life Tree : Sus scrofa
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Laurasiatheria N E > Cetartiodactyla N E > Suina N E > Suidae N E > Sus N E > Sus scrofa N EMWLLPLVLTS LASSATWAGQ PASPPVVDTA QGRVLGKYVS LEGLAQPVAV FLGVPFAKPP LGSLRFAPPQ PAEPWSFVKN TTSYPPMCCQ DPVVEQMTSD LFTNGKERLT LEFSEDCLYL NIYTPADLTK RGRLPVMVWI HGGGLVLGGA PMYDGVVLAA HENVVVVAIQ YRLGIWGFFS TGDEHSRGNW GHLDQVAALH WVQENIANFG GDPGSVTIFG ESAGGESVSV LVLSPLAKNL FHRAISESGV ALTVALVRKD MKAAAKQIAV LAGCKTTTSA VFVHCLRQKS EDELLDLTLK MKFLTLDFHG DQRESHPFLP TVVDGVLLPK MPEEILAEKD FNTVPYIVGI NKQEFGWLLP TMMGFPLSEG KLDQKTATSL LWKSYPIANI PEELTPVATD KYLGGTDDPV KKKDLFLDLM GDVVFGVPSV TVARQHRDAG APTYMYEFQY RPSFSSDKKP KTVIGDHGDE IFSVFGFPLL KGDAPEEEVS LSKTVMKFWA NFARSGNPNG EGLPHWPMYD QEEGYLQIGV NTQAAKRLKG EEVAFWNDLL SKEAAKKPPK IKHAEL
| Title : Pig liver esterases PLE1 and PLE6: heterologous expression, hydrolysis of common antibiotics and pharmacological consequences - Zhou_2019_Sci.Rep_9_15564 |
| Author(s) : Zhou Q , Xiao Q , Zhang Y , Wang X , Xiao Y , Shi D |
| Ref : Sci Rep , 9 :15564 , 2019 |
| Abstract : |
| PubMedSearch : Zhou_2019_Sci.Rep_9_15564 |
| PubMedID: 31664043 |
| Gene_locus related to this paper: pig-EST1 , pig-a0a1s6l967 |
| Title : Regioselective ester cleavage of di-(2-ethylhexyl) trimellitates by porcine liver esterase - Hollerer_2018_Toxicol.In.Vitro_47_178 |
| Author(s) : Hollerer C , Becker G , Goen T , Eckert E |
| Ref : Toxicol In Vitro , 47 :178 , 2018 |
| Abstract : |
| PubMedSearch : Hollerer_2018_Toxicol.In.Vitro_47_178 |
| PubMedID: 29180039 |
| Gene_locus related to this paper: pig-a9gyw6 , pig-EST1 , pig-a0a1s6l948 , pig-a0a1s6l967 |
| Title : Breed Differences in Pig Liver Esterase (PLE) between Tongcheng (Chinese Local Breed) and Large White Pigs - Xiao_2018_Sci.Rep_8_16364 |
| Author(s) : Xiao Q , Zhou Q , Yang L , Tian Z , Wang X , Xiao Y , Shi D |
| Ref : Sci Rep , 8 :16364 , 2018 |
| Abstract : |
| PubMedSearch : Xiao_2018_Sci.Rep_8_16364 |
| PubMedID: 30397234 |
| Gene_locus related to this paper: pig-a9gyw6 , pig-EST1 , pig-PLE1 , pig-a0a1s6l948 , pig-a0a1s6l959 , pig-a0a1s6l967 |
| Title : Third-Generation Sequencing and Analysis of Four Complete Pig Liver Esterase Gene Sequences in Clones Identified by Screening BAC Library - Zhou_2016_PLoS.One_11_e0163295 |
| Author(s) : Zhou Q , Sun W , Liu X , Wang X , Xiao Y , Bi D , Yin J , Shi D |
| Ref : PLoS ONE , 11 :e0163295 , 2016 |
| Abstract : |
| PubMedSearch : Zhou_2016_PLoS.One_11_e0163295 |
| PubMedID: 27695062 |
| Gene_locus related to this paper: pig-EST1 , pig-PLE1 , pig-a0a1s6l948 , pig-a0a1s6l959 , pig-a0a1s6l967 |
| Title : Selective production of 1-monocaprin by porcine liver carboxylesterase-catalyzed esterification: Its enzyme kinetics and catalytic performance - Park_2016_Enzyme.Microb.Technol_82_51 |
| Author(s) : Park KM , Lee JH , Hong SC , Kwon CW , Jo M , Choi SJ , Kim K , Chang PS |
| Ref : Enzyme Microb Technol , 82 :51 , 2016 |
| Abstract : |
| PubMedSearch : Park_2016_Enzyme.Microb.Technol_82_51 |
| PubMedID: 26672448 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Inhibition of porcine liver carboxylesterase by phosphorylated flavonoids - Wei_2013_Chem.Biol.Interact_204_75 |
| Author(s) : Wei Y , Peng AY , Huang J |
| Ref : Chemico-Biological Interactions , 204 :75 , 2013 |
| Abstract : |
| PubMedSearch : Wei_2013_Chem.Biol.Interact_204_75 |
| PubMedID: 23643881 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Characterization and optimization of carboxylesterase-catalyzed esterification between capric acid and glycerol for the production of 1-monocaprin in reversed micellar system - Park_2010_N.Biotechnol_27_46 |
| Author(s) : Park KM , Kwon OT , Ahn SM , Lee J , Chang PS |
| Ref : N Biotechnol , 27 :46 , 2010 |
| Abstract : |
| PubMedSearch : Park_2010_N.Biotechnol_27_46 |
| PubMedID: 19931658 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Porcine Liver Carboxylesterase Requires Polyisoprenylation for High Affinity Binding to Cysteinyl Substrates - Lamango_2009_Open.Enzym.Inhib.J_2_12 |
| Author(s) : Lamango NS , Duverna R , Zhang W , Ablordeppey SY |
| Ref : Open Enzym Inhib J , 2 :12 , 2009 |
| Abstract : |
| PubMedSearch : Lamango_2009_Open.Enzym.Inhib.J_2_12 |
| PubMedID: 20664805 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Liver prenylated methylated protein methyl esterase is the same enzyme as Sus scrofa carboxylesterase - Oboh_2008_J.Biochem.Mol.Toxicol_22_51 |
| Author(s) : Oboh OT , Lamango NS |
| Ref : J Biochem Mol Toxicol , 22 :51 , 2008 |
| Abstract : |
| PubMedSearch : Oboh_2008_J.Biochem.Mol.Toxicol_22_51 |
| PubMedID: 18273909 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Inhibition of porcine liver carboxylesterase by a new flavone glucoside isolated from Deverra scoparia - Djeridane_2008_Chem.Biol.Interact_172_22 |
| Author(s) : Djeridane A , Brunel JM , Vidal N , Yousfi M , Ajandouz EH , Stocker P |
| Ref : Chemico-Biological Interactions , 172 :22 , 2008 |
| Abstract : |
| PubMedSearch : Djeridane_2008_Chem.Biol.Interact_172_22 |
| PubMedID: 18163984 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Isoenzymes of pig-liver esterase reveal striking differences in enantioselectivities - |
| Author(s) : Hummel A , Brusehaber E , Bottcher D , Trauthwein H , Doderer K , Bornscheuer UT |
| Ref : Angew Chem Int Ed Engl , 46 :8492 , 2007 |
| PubMedID: 17902087 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Nucleoside ester prodrug substrate specificity of liver carboxylesterase - Landowski_2006_J.Pharmacol.Exp.Ther_316_572 |
| Author(s) : Landowski CP , Lorenzi PL , Song X , Amidon GL |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 316 :572 , 2006 |
| Abstract : |
| PubMedSearch : Landowski_2006_J.Pharmacol.Exp.Ther_316_572 |
| PubMedID: 16223870 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Phenolic extracts from various Algerian plants as strong inhibitors of porcine liver carboxylesterase - Djeridane_2006_J.Enzyme.Inhib.Med.Chem_21_719 |
| Author(s) : Djeridane A , Yousfi M , Nadjemi B , Maamri S , Djireb F , Stocker P |
| Ref : J Enzyme Inhib Med Chem , 21 :719 , 2006 |
| Abstract : |
| PubMedSearch : Djeridane_2006_J.Enzyme.Inhib.Med.Chem_21_719 |
| PubMedID: 17252945 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Purification and characterization of retinyl ester hydrolase as a member of the non-specific carboxylesterase supergene family - Schindler_1998_Eur.J.Biochem_251_863 |
| Author(s) : Schindler R , Mentlein R , Feldheim W |
| Ref : European Journal of Biochemistry , 251 :863 , 1998 |
| Abstract : |
| PubMedSearch : Schindler_1998_Eur.J.Biochem_251_863 |
| PubMedID: 9490062 |
| Gene_locus related to this paper: human-CES1 , pig-EST1 |
| Title : Purification and molecular cloning of porcine intestinal glycerol-ester hydrolase--evidence for its identity with carboxylesterase - David_1998_Eur.J.Biochem_257_142 |
| Author(s) : David L , Guo XJ , Villard C , Moulin A , Puigserver A |
| Ref : European Journal of Biochemistry , 257 :142 , 1998 |
| Abstract : |
| PubMedSearch : David_1998_Eur.J.Biochem_257_142 |
| PubMedID: 9799112 |
| Gene_locus related to this paper: pig-EST1 |
| Title : Purification, cloning, and expression of a human enzyme with acyl coenzyme A: cholesterol acyltransferase activity, which is identical to liver carboxylesterase - Becker_1994_Arterioscler.Thromb_14_1346 |
| Author(s) : Becker A , Bottcher A , Lackner KJ , Fehringer P , Notka F , Aslanidis C , Schmitz G |
| Ref : Arterioscler Thromb , 14 :1346 , 1994 |
| Abstract : |
| PubMedSearch : Becker_1994_Arterioscler.Thromb_14_1346 |
| PubMedID: 8049197 |
| Gene_locus related to this paper: human-CES1 , pig-EST1 |
| Title : A note on the identity of porcine liver carboxylesterase and prolyl-beta-naphthylamidase - Heymann_1993_Biol.Chem.Hoppe.Seyler_374_1033 |
| Author(s) : Heymann E , Peter K |
| Ref : Biol Chem Hoppe Seyler , 374 :1033 , 1993 |
| Abstract : |
| PubMedSearch : Heymann_1993_Biol.Chem.Hoppe.Seyler_374_1033 |
| PubMedID: 8292262 |
| Gene_locus related to this paper: pig-EST1 |
| Title : The nucleotide and deduced amino acid sequences of porcine liver proline- beta-naphthylamidase. Evidence for the identity with carboxylesterase - Matsushima_1991_FEBS.Lett_293_37 |
| Author(s) : Matsushima M , Inoue H , Ichinose M , Tsukada S , Miki K , Kurokawa K , Takahashi T , Takahashi K |
| Ref : FEBS Letters , 293 :37 , 1991 |
| Abstract : |
| PubMedSearch : Matsushima_1991_FEBS.Lett_293_37 |
| PubMedID: 1959668 |
| Gene_locus related to this paper: pig-EST1 |