Title : Tin (IV) chloride-promoted one-pot synthesis of novel tacrine analogues - Hu_2011_Molecules_16_1878 |
Author(s) : Hu H , Song L , Fang Q , Zheng J , Meng Z , Luo Y |
Ref : Molecules , 16 :1878 , 2011 |
Abstract :
A facile synthesis of potential acetylcholinesterase (AChE) inhibitors, the tacrine analogues 3a-p, has been accomplished by direct cyclocondensation of 1-aryl-4-cyano-5-aminopyrazole with beta-ketoesters using tin(IV) chloride as catalyst. The structures of all the compounds have been confirmed by IR, (1)H- and (1)(3)C-NMR. |
PubMedSearch : Hu_2011_Molecules_16_1878 |
PubMedID: 21343890 |
Hu H, Song L, Fang Q, Zheng J, Meng Z, Luo Y (2011)
Tin (IV) chloride-promoted one-pot synthesis of novel tacrine analogues
Molecules
16 :1878
Hu H, Song L, Fang Q, Zheng J, Meng Z, Luo Y (2011)
Molecules
16 :1878