Kwon_2025_Fibers.Polym_26_2947

Fabrics treated with organic catalysts containing guanidine groups have shown promise as protective materials against nerve agents. This study proposes a simple method for incorporating guanidine groups onto cotton fabric surfaces using polyhexamethylene guanidine (PHMG) to develop protective materials against nerve agents. The detoxification performance of the prepared fabric was assessed using nerve agent simulants, including dimethyl methylphosphonate (DMMP) and diisopropylfluorophosphate (DFP). PHMG-treated cotton fabric decontaminated 27.6% of DMMP and 67.2% of DFP at 32 C in 2 h, with half lives of 401 and 229 min, respectively. These findings indicate that PHMG-treated cotton fabric exhibits strong detoxification performance against nerve agent simulants. Therefore, PHMG can be considered an effective organic catalyst for the simple and facile fabrication of protective materials against nerve agents.