| Title : Structure and conformation activity relationships of heterocyclic acetylcholine analogues. X. The inhibitory effect of 3-quinuclidinyl benzilates on cardiac muscarinic receptors - Lambrecht_1980_Arzneimittelforschung_30_2113 |
| Author(s) : Lambrecht G |
| Ref : Arzneimittelforschung , 30 :2113 , 1980 |
|
Abstract :
The tertiary and quaternary enantiomers of 3-quinuclidinyl benzilate (QNB) were tested for atropine-like activity on the electrically stimulated guinea-pig atrium preparation. The (R)-isomers had higher affinity for muscarine-sensitive acetylcholine receptors than their corresponding (S)-analogues. |
| PubMedSearch : Lambrecht_1980_Arzneimittelforschung_30_2113 |
| PubMedID: 7194070 |
Lambrecht G (1980)
Structure and conformation activity relationships of heterocyclic acetylcholine analogues. X. The inhibitory effect of 3-quinuclidinyl benzilates on cardiac muscarinic receptors
Arzneimittelforschung
30 :2113
Lambrecht G (1980)
Arzneimittelforschung
30 :2113