Lambrecht G

General

Full name : Lambrecht Gunter

First name : Gunter

Mail : Pharmakologisches Institut fur Naturwissenschaftler, Universitat Frankfurt, Frankfurt\/Main

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Country : Germany

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References (126)

Title : Functional characterization of muscarinic autoreceptors in rat and human neocortex - Stoll_2009_J.Neurochem_110_837
Author(s) : Stoll C , Eltze M , Lambrecht G , Zentner J , Feuerstein TJ , Jackisch R
Ref : Journal of Neurochemistry , 110 :837 , 2009
PubMedID: 19493162

Title : Characterization of muscarinic autoreceptors in the rabbit hippocampus and caudate nucleus - Stoll_2003_Neurochem.Res_28_413
Author(s) : Stoll C , Schwarzwalder U , Johann S , Lambrecht G , Hertting G , Feuerstein TJ , Jackisch R
Ref : Neurochem Res , 28 :413 , 2003
PubMedID: 12675124

Title : Structure-activity relationships of dimethindene derivatives as new M2-selective muscarinic receptor antagonists - Bohme_2003_J.Med.Chem_46_856
Author(s) : Bohme TM , Keim C , Kreutzmann K , Linder M , Dingermann T , Dannhardt G , Mutschler E , Lambrecht G
Ref : Journal of Medicinal Chemistry , 46 :856 , 2003
PubMedID: 12593665

Title : Design and pharmacology of quinuclidine derivatives as M2-selective muscarinic receptor ligands - Bohme_2001_Bioorg.Med.Chem.Lett_11_1241
Author(s) : Bohme TM , Keim C , Dannhardt G , Mutschler E , Lambrecht G
Ref : Bioorganic & Medicinal Chemistry Lett , 11 :1241 , 2001
PubMedID: 11354386

Title : NF449: a subnanomolar potency antagonist at recombinant rat P2X1 receptors - Braun_2001_Naunyn.Schmiedebergs.Arch.Pharmacol_364_285
Author(s) : Braun K , Rettinger J , Ganso M , Kassack M , Hildebrandt C , Ullmann H , Nickel P , Schmalzing G , Lambrecht G
Ref : Naunyn Schmiedebergs Arch Pharmacol , 364 :285 , 2001
PubMedID: 11521173

Title : The novel pyridoxal-5'-phosphate derivative PPNDS potently antagonizes activation of P2X(1) receptors - Lambrecht_2000_Eur.J.Pharmacol_387_R19
Author(s) : Lambrecht G , Rettinger J , Baumert HG , Czeche S , Damer S , Ganso M , Hildebrandt C , Niebel B , Spatz-Kumbel G , Schmalzing G , Mutschler E
Ref : European Journal of Pharmacology , 387 :R19 , 2000
PubMedID: 10650184

Title : Functional role of muscarinic M(2) receptors in alpha,beta-methylene ATP induced, neurogenic contractions in guinea-pig ileum - Sawyer_2000_Br.J.Pharmacol_129_1458
Author(s) : Sawyer GW , Lambrecht G , Ehlert FJ
Ref : British Journal of Pharmacology , 129 :1458 , 2000
PubMedID: 10742302

Title : Muscarinic properties of compounds related to arecaidine propargyl ester - Tumiatti_2000_Arzneimittelforschung_50_11
Author(s) : Tumiatti V , Wehrle J , Hildebrandt C , Moser U , Dannhardt G , Mutschler E , Lambrecht G
Ref : Arzneimittelforschung , 50 :11 , 2000
PubMedID: 10683710

Title : Neuronal soma-dendritic and prejunctional M1-M4 receptors in gastrointestinal and genitourinary smooth muscle - Lambrecht_1999_Life.Sci_64(6-7)_403
Author(s) : Lambrecht G , Gross J , Mutschler E
Ref : Life Sciences , 64 :403 , 1999
PubMedID: 10069503

Title : Poster: Stereoselective interaction of trihexyphenidyl and related compounds with muscarinic receptors -
Author(s) : Gross J , Pfaff O , Rachel D , Tacke R , Leis A , Ruhlmann K , Waelbroeck M , Mutschler E , Lambrecht G
Ref : Life Sciences , 64 :593 , 1999
PubMedID:

Title : Poster: Binding affinities of new dimethindene analogues at five muscarinic receptor subtypes -
Author(s) : Keim C , Bohme T , Dannhardt G , Niebel B , Lambrecht G , Mutschler E
Ref : Life Sciences , 64 :556 , 1999
PubMedID:

Title : Poster: Facilitation of acetylcholine release from myenteric neurones by alpha,beta-methylene ATP causes a contraction of the guinea-pig ileum via postjunctional M3 receptors -
Author(s) : Czeche S , Niebel B , Mutschler E , Lambrecht G
Ref : Life Sciences , 64 :592 , 1999
PubMedID:

Title : M2 receptor binding of the selective antagonist AF-DX 384: possible involvement of the common allosteric site - Trankle_1998_Mol.Pharmacol_53_304
Author(s) : Trankle C , Andresen I , Lambrecht G , Mohr K
Ref : Molecular Pharmacology , 53 :304 , 1998
PubMedID: 9463489

Title : NF279: a novel potent and selective antagonist of P2X receptor-mediated responses - Damer_1998_Eur.J.Pharmacol_350_R5
Author(s) : Damer S , Niebel B , Czeche S , Nickel P , Ardanuy U , Schmalzing G , Rettinger J , Mutschler E , Lambrecht G
Ref : European Journal of Pharmacology , 350 :R5 , 1998
PubMedID: 9683026

Title : Poster: Stereoselective interaction of p-fluoro-trihexyphenidyl and its methiodide with four muscarinic receptor subtypes -
Author(s) : Lambrecht G , Pfaff O , Aasen AJ , Sjo P , Mutschler E , Waelbroeck M
Ref : Life Sciences , 60 :1166 , 1997
PubMedID:

Title : Poster: Antimuscarinic properties of the stereoisomers of glycopyrronium bromide -
Author(s) : Czeche S , Elgert M , Noe C , Waelbroeck M , Mutschler E , Lambrecht G
Ref : Life Sciences , 60 :1167 , 1997
PubMedID:

Title : Poster: Functional characterisation of PD102807: A novel M4-selective muscarinic antagonist -
Author(s) : Gross J , Augelli-Szafran CE , Czeche S , Friebe T , Jaen JC , Penvose-Yi JR , Schwarz RD , Mutschler E , Lambrecht G
Ref : Life Sciences , 60 :1168 , 1997
PubMedID:

Title : Characterization of postjunctional muscarinic receptors mediating contraction in rat anococcygeus muscle - Weiser_1997_Naunyn.Schmiedebergs.Arch.Pharmacol_356_671
Author(s) : Weiser M , Mutschler E , Lambrecht G
Ref : Naunyn Schmiedebergs Arch Pharmacol , 356 :671 , 1997
PubMedID: 9402048

Title : Quantitative colorimetric and gas chromatographic determination of arecaidine propargyl ester - Langer_1997_J.Chromatogr.B.Biomed.Sci.Appl_692_345
Author(s) : Langer K , Lambrecht G , Moser U , Mutschler E , Kreuter J
Ref : Journal of Chromatography B Biomed Sci Appl , 692 :345 , 1997
PubMedID: 9188823

Title : Evidence for muscarinic M4 receptors mediating nonadrenergic noncholinergic relaxations in rabbit anococcygeus muscle - Gross_1997_Naunyn.Schmiedebergs.Arch.Pharmacol_356_505
Author(s) : Gross J , Mutschler E , Lambrecht G
Ref : Naunyn Schmiedebergs Arch Pharmacol , 356 :505 , 1997
PubMedID: 9349639

Title : Poster: Functional characterization of postjunctional muscarinic receptors in rat anococcygeus muscle -
Author(s) : Weiser M , Waelbroeck M , Lambrecht G , Mutschler E
Ref : Life Sciences , 60 :1192 , 1997
PubMedID:

Title : Stereoselective interaction of uncharged esters at four muscarinic receptor subtypes - Waelbroeck_1996_Eur.J.Pharmacol_303_221
Author(s) : Waelbroeck M , Hou X , Wehrle J , Mutschler E , Van Tilburg E , Menge W , Timmerman H , Lambrecht G
Ref : European Journal of Pharmacology , 303 :221 , 1996
PubMedID: 8813573

Title : Stereoselective recognition of the enantiomers of phenglutarimide and of six related compounds by four muscarinic receptor subtypes - Waelbroeck_1996_Br.J.Pharmacol_119_1319
Author(s) : Waelbroeck M , Lazareno S , Pfaff O , Friebe T , Tastenoy M , Mutschler E , Lambrecht G
Ref : British Journal of Pharmacology , 119 :1319 , 1996
PubMedID: 8968538

Title : Influence of monovalent cations on the binding of a charged and an uncharged ('carbo'-)muscarinic antagonist to muscarinic receptors - Hou_1996_Br.J.Pharmacol_117_955
Author(s) : Hou X , Wehrle J , Menge W , Ciccarelli E , Wess J , Mutschler E , Lambrecht G , Timmerman H , Waelbroeck M
Ref : British Journal of Pharmacology , 117 :955 , 1996
PubMedID: 8851517

Title : Design and pharmacology of selective P2-purinoceptor antagonists - Lambrecht_1996_J.Auton.Pharmacol_16_341
Author(s) : Lambrecht G
Ref : J Auton Pharmacol , 16 :341 , 1996
PubMedID: 9131412

Title : Aliphatic and heterocyclic analogues of arecaidine propargyl ester. Structure-activity relationships of mono- and bivalent ligands at muscarinic M1 (M4), M2 and M3 receptor subtypes - Moser_1995_Arzneimittelforschung_45_449
Author(s) : Moser U , Gubitz C , Galvan M , Immel-Sehr A , Lambrecht G , Mutschler E
Ref : Arzneimittelforschung , 45 :449 , 1995
PubMedID: 7779140

Title : Muscarinic receptor subtypes--pharmacological, molecular biological and therapeutical aspects -
Author(s) : Mutschler E , Moser U , Wess J , Lambrecht G
Ref : Pharm Acta Helv , 69 :243 , 1995
PubMedID: 7651968

Title : Regioisomeric 5(3)-aminomethyl-3(5)-phenylisoxazoles: synthesis, spectroscopic discrimination, and muscarinic activity - Dannhardt_1995_Arch.Pharm.(Weinheim)_328_437
Author(s) : Dannhardt G , Lambrecht G , Laufer S , Mutschler E , Schweiger J
Ref : Arch Pharm (Weinheim) , 328 :437 , 1995
PubMedID: 7611839

Title : The design and pharmacology of novel selective muscarinic agonists and antagonists - Lambrecht_1995_Life.Sci_56(11-12)_815
Author(s) : Lambrecht G , Gross J , Hacksell U , Hermanni U , Hildebrandt C , Hou X , Moser U , Nilsson BM , Pfaff O , Waelbroeck M , Wehrle J , Mutschler E
Ref : Life Sciences , 56(11-12) :815 , 1995
PubMedID: 10188780

Title : Poster: Functional characterization of muscarinic receptors in rat duodenum -
Author(s) : Pfaff O , Gross J , Waelbroeck M , Mutschler E , Lambrecht G
Ref : Life Sciences , 56(11-12) :1038 , 1995
PubMedID:

Title : Poster: Functional characterization of neuronal muscarinic receptors in rabbit anococcygeus muscle -
Author(s) : Gross J , Waelbroeck M , Mutschler E , Lambrecht G
Ref : Life Sciences , 56(11-12) :1038 , 1995
PubMedID:

Title : Inhibitory action of PPADS on relaxant responses to adenine nucleotides or electrical field stimulation in guinea-pig taenia coli and rat duodenum - Windscheif_1995_Br.J.Pharmacol_115_1509
Author(s) : Windscheif U , Pfaff O , Ziganshin AU , Hoyle CH , Baumert HG , Mutschler E , Burnstock G , Lambrecht G
Ref : British Journal of Pharmacology , 115 :1509 , 1995
PubMedID: 8564212

Title : Poster: Pharmacology of selective muscarinic ligands related to McN-A-343 -
Author(s) : Moser U , Wehrle J , Hacksell U , Nilsson BM , Tumiatti V , Lambrecht G , Mutschler E
Ref : Life Sciences , 56(11-12) :1006 , 1995
PubMedID:

Title : The (S)-(+)-enantiomer of dimethindene: a novel M2-selective muscarinic receptor antagonist - Pfaff_1995_Eur.J.Pharmacol_286_229
Author(s) : Pfaff O , Hildebrandt C , Waelbroeck M , Hou X , Moser U , Mutschler E , Lambrecht G
Ref : European Journal of Pharmacology , 286 :229 , 1995
PubMedID: 8608784

Title : Anticholinergic intoxication with commercially available thorn apple tea - Coremans_1994_J.Toxicol.Clin.Toxicol_32_589
Author(s) : Coremans P , Lambrecht G , Schepens P , Vanwelden J , Verhaegen H
Ref : J Toxicol Clinical Toxicology , 32 :589 , 1994
PubMedID: 7932919

Title : Binding and functional properties of hexocyclium and sila-hexocyclium derivatives to muscarinic receptor subtypes - Waelbroeck_1994_Br.J.Pharmacol_112_505
Author(s) : Waelbroeck M , Camus J , Tastenoy M , Feifel R , Mutschler E , Tacke R , Strohmann C , Rafeiner K , Rodrigues de Miranda JF , Lambrecht G
Ref : British Journal of Pharmacology , 112 :505 , 1994
PubMedID: 8075869

Title : Synthesis and muscarinic activity of isoxazole-substituted 1,2,5,6-tetrahydropyridines -
Author(s) : Dannhardt G , Schweiger J , Lambrecht G , Mutschler E
Ref : Arch Pharm (Weinheim) , 327 :751 , 1994
PubMedID: 7840738

Title : Vasoconstrictor and vasodilator responses to various agonists in the rat perfused mesenteric arterial bed: selective inhibition by PPADS of contractions mediated via P2x-purinoceptors - Windscheif_1994_Br.J.Pharmacol_113_1015
Author(s) : Windscheif U , Ralevic V , Baumert HG , Mutschler E , Lambrecht G , Burnstock G
Ref : British Journal of Pharmacology , 113 :1015 , 1994
PubMedID: 7858843

Title : Investigation of the actions of PPADS, a novel P2x-purinoceptor antagonist, in the guinea-pig isolated vas deferens - McLaren_1994_Br.J.Pharmacol_111_913
Author(s) : McLaren GJ , Lambrecht G , Mutschler E , Baumert HG , Sneddon P , Kennedy C
Ref : British Journal of Pharmacology , 111 :913 , 1994
PubMedID: 8019769

Title : Pharmacokinetic and pharmacodynamic aspects of an ophthalmic pilocarpine nanoparticle-delivery-system - Zimmer_1994_Pharm.Res_11_1435
Author(s) : Zimmer A , Mutschler E , Lambrecht G , Mayer D , Kreuter J
Ref : Pharm Res , 11 :1435 , 1994
PubMedID: 7855048

Title : Characterization of the prejunctional muscarinic receptors mediating inhibition of evoked release of endogenous noradrenaline in rabbit isolated vas deferens - Grimm_1994_Naunyn.Schmiedebergs.Arch.Pharmacol_349_1
Author(s) : Grimm U , Fuder H , Moser U , Bumert HG , Mutschler E , Lambrecht G
Ref : Naunyn Schmiedebergs Arch Pharmacol , 349 :1 , 1994
PubMedID: 8139696

Title : Muscarinic receptors: focus on presynaptic mechanisms and recently developed novel agonists and antagonists -
Author(s) : Grimm U , Moser U , Mutschler E , Lambrecht G
Ref : Pharmazie , 49 :711 , 1994
PubMedID: 7816897

Title : Characterization of muscarinic receptors mediating vasodilation in rat perfused kidney - Eltze_1993_Eur.J.Pharmacol_238_343
Author(s) : Eltze M , Ullrich B , Mutschler E , Moser U , Bungardt E , Friebe T , Gubitz C , Tacke R , Lambrecht G
Ref : European Journal of Pharmacology , 238 :343 , 1993
PubMedID: 8405103

Title : New functionally selective muscarinic agonists - Lambrecht_1993_Life.Sci_52(5-6)_481
Author(s) : Lambrecht G , Moser U , Grimm U , Pfaff O , Hermanni U , Hildebrandt C , Waelbroeck M , Christophe J , Mutschler E
Ref : Life Sciences , 52 :481 , 1993
PubMedID: 7680092

Title : Poster: New functionally selective M1 agonists related to McN-A-343 -
Author(s) : Moser U , Lambrecht G , Mellin C , Mutschler E
Ref : Life Sciences , 52(5-6) :550 , 1993
PubMedID:

Title : Thermodynamics of antagonist binding to rat muscarinic M2 receptors: antimuscarinics of the pridinol, sila-pridinol, diphenidol and sila-diphenidol type - Waelbroeck_1993_Br.J.Pharmacol_109_360
Author(s) : Waelbroeck M , Camus J , Tastenoy M , Lambrecht G , Mutschler E , Kropfgans M , Sperlich J , Wiesenberger F , Tacke R , Christophe J
Ref : British Journal of Pharmacology , 109 :360 , 1993
PubMedID: 8102927

Title : Poster: Functional characterization of muscarinic receptors in rabbit peripheral lung -
Author(s) : Vockert E , Egerer HP , Tacke R , Lambrecht G , Mutschler E
Ref : Life Sciences , 52(5-6) :551 , 1993
PubMedID:

Title : WAL 2014--a muscarinic agonist with preferential neuron-stimulating properties - Ensinger_1993_Life.Sci_52(5-6)_473
Author(s) : Ensinger HA , Doods HN , Immel-Sehr AR , Kuhn FJ , Lambrecht G , Mendla KD , Muller RE , Mutschler E , Sagrada A , Walther G , Hammer R
Ref : Life Sciences , 52 :473 , 1993
PubMedID: 8441328

Title : Poster: Characterization of the vasodilatory muscarinic receptor in perfused rat kidney by the use of agonists and antagonists -
Author(s) : Eltze M , Mutschler E , Moser U , Friebe T , Gubitz C , Tacke R , Lambrecht G
Ref : Life Sciences , 52(5-6) :579 , 1993
PubMedID:

Title : PPADS selectively antagonizes P2X-purinoceptor-mediated responses in the rabbit urinary bladder - Ziganshin_1993_Br.J.Pharmacol_110_1491
Author(s) : Ziganshin AU , Hoyle CH , Bo X , Lambrecht G , Mutschler E , Baumert HG , Burnstock G
Ref : British Journal of Pharmacology , 110 :1491 , 1993
PubMedID: 8306091

Title : Poster: Muscarinic inhibition of noradrenaline release evoked by field stimulation on rabbit isolated vas deferens -
Author(s) : Grimm U , Fuder H , Mutschler E , Lambrecht G
Ref : Life Sciences , 52(5-6) :563 , 1993
PubMedID:

Title : Affinity profiles of pizotifen, ketotifen and other tricyclic antimuscarinics at muscarinic receptor subtypes M1, M2 and M3 - Eltze_1992_Eur.J.Pharmacol_211_283
Author(s) : Eltze M , Mutschler E , Lambrecht G
Ref : European Journal of Pharmacology , 211 :283 , 1992
PubMedID: 1377628

Title : Stereoselective interaction of procyclidine, hexahydro-difenidol, hexbutinol and oxyphencyclimine, and of related antagonists, with four muscarinic receptors - Waelbroeck_1992_Eur.J.Pharmacol_227_33
Author(s) : Waelbroeck M , Camus J , Tastenoy M , Mutschler E , Strohmann C , Tacke R , Schjelderup L , Aasen A , Lambrecht G , Christophe J
Ref : European Journal of Pharmacology , 227 :33 , 1992
PubMedID: 1426023

Title : Cryptolepis sanguinolenta: antimuscarinic properties of cryptolepine and the alkaloid fraction at M1, M2 and M3 receptors - Rauwald_1992_Planta.Med_58_486
Author(s) : Rauwald HW , Kober M , Mutschler E , Lambrecht G
Ref : Planta Med , 58 :486 , 1992
PubMedID: 1484884

Title : PPADS, a novel functionally selective antagonist of P2 purinoceptor-mediated responses - Lambrecht_1992_Eur.J.Pharmacol_217_217
Author(s) : Lambrecht G , Friebe T , Grimm U , Windscheif U , Bungardt E , Hildebrandt C , Baumert HG , Spatz-Kumbel G , Mutschler E
Ref : European Journal of Pharmacology , 217 :217 , 1992
PubMedID: 1330591

Title : Characterization of muscarinic receptors mediating vasodilation in guinea-pig ileum submucosal arterioles by the use of computer-assisted videomicroscopy - Bungardt_1992_Eur.J.Pharmacol_213_53
Author(s) : Bungardt E , Vockert E , Feifel R , Moser U , Tacke R , Mutschler E , Lambrecht G , Surprenant A
Ref : European Journal of Pharmacology , 213 :53 , 1992
PubMedID: 1499657

Title : Binding affinities of hexahydro-difenidol and hexahydro-sila-difenidol analogues at four muscarinic receptor subtypes: constitutional and stereochemical aspects - Waelbroeck_1991_Eur.J.Pharmacol_206_95
Author(s) : Waelbroeck M , Camus J , Tastenoy M , Mutschler E , Strohmann C , Tacke R , Lambrecht G , Christophe J
Ref : European Journal of Pharmacology , 206 :95 , 1991
PubMedID: 2065719

Title : Stereoselectivity of (R)- and (S)-hexahydro-difenidol binding to neuroblastoma M1, cardiac M2, pancreatic M3, and striatum M4 muscarinic receptors - Waelbroeck_1991_Chirality_3_118
Author(s) : Waelbroeck M , Camus J , Tastenoy M , Mutschler E , Strohmann C , Tacke R , Lambrecht G , Christophe J
Ref : Chirality , 3 :118 , 1991
PubMedID: 1863523

Title : Selective labelling of muscarinic M1 receptors in calf superior cervical ganglia by [3H](+\/-)-telenzepine - Feifel_1991_Eur.J.Pharmacol_195_115
Author(s) : Feifel R , Rodrigues de Miranda JF , Strohmann C , Tacke R , Aasen AJ , Mutschler E , Lambrecht G
Ref : European Journal of Pharmacology , 195 :115 , 1991
PubMedID: 2065706

Title : Selectivity profile of the novel muscarinic antagonist UH-AH 37 determined by the use of cloned receptors and isolated tissue preparations - Wess_1991_Br.J.Pharmacol_102_246
Author(s) : Wess J , Lambrecht G , Mutschler E , Brann MR , Dorje F
Ref : British Journal of Pharmacology , 102 :246 , 1991
PubMedID: 2043926

Title : Pharmacological characterization of the vascular muscarinic receptors mediating relaxation and contraction in rabbit aorta - Jaiswal_1991_J.Pharmacol.Exp.Ther_258_842
Author(s) : Jaiswal N , Lambrecht G , Mutschler E , Tacke R , Malik KU
Ref : Journal of Pharmacology & Experimental Therapeutics , 258 :842 , 1991
PubMedID: 1716312

Title : Effect of extracellular calcium concentration on potency of muscarinic agonists at M1 and M2 receptors in rabbit vas deferens - Dorje_1991_Eur.J.Pharmacol_203_417
Author(s) : Dorje F , Rettenmayr NM , Mutschler E , Lambrecht G
Ref : European Journal of Pharmacology , 203 :417 , 1991
PubMedID: 1723047

Title : Antagonist binding profiles of five cloned human muscarinic receptor subtypes - Dorje_1991_J.Pharmacol.Exp.Ther_256_727
Author(s) : Dorje F , Wess J , Lambrecht G , Tacke R , Mutschler E , Brann MR
Ref : Journal of Pharmacology & Experimental Therapeutics , 256 :727 , 1991
PubMedID: 1994002

Title : Stereoselectivity of procyclidine binding to muscarinic receptor subtypes M1, M2 and M4 - Waelbroeck_1990_Eur.J.Pharmacol_189_135
Author(s) : Waelbroeck M , Camus J , Tastenoy M , Lambrecht G , Mutschler E , Tacke R , Christophe J
Ref : European Journal of Pharmacology , 189 :135 , 1990
PubMedID: 2253700

Title : Stereoselective inhibition of muscarinic receptor subtypes by the enantiomers of hexahydro-difenidol and acetylenic analogues - Feifel_1990_Br.J.Pharmacol_99_455
Author(s) : Feifel R , Wagner-Roder M , Strohmann C , Tacke R , Waelbroeck M , Christophe J , Mutschler E , Lambrecht G
Ref : British Journal of Pharmacology , 99 :455 , 1990
PubMedID: 2331578

Title : Pharmacokinetic properties of the antimuscarinic drug [3H]-hexahydro-sila-difenidol in the rat - Rettenmayr_1990_Naunyn.Schmiedebergs.Arch.Pharmacol_342_146
Author(s) : Rettenmayr NM , Rodrigues de Miranda JF , Rijntjes NV , Russel FG , van Ginneken CA , Strohmann C , Tacke R , Lambrecht G , Mutschler E
Ref : Naunyn Schmiedebergs Arch Pharmacol , 342 :146 , 1990
PubMedID: 2234099

Title : Novel pharmacological profile of muscarinic receptors mediating contraction of the guinea-pig uterus - Dorje_1990_Naunyn.Schmiedebergs.Arch.Pharmacol_342_284
Author(s) : Dorje F , Friebe T , Tacke R , Mutschler E , Lambrecht G
Ref : Naunyn Schmiedebergs Arch Pharmacol , 342 :284 , 1990
PubMedID: 2280796

Title : Human gastric mucosa expresses glandular M3 subtype of muscarinic receptors - Pfeiffer_1990_Dig.Dis.Sci_35_1468
Author(s) : Pfeiffer A , Hanack C , Kopp R , Tacke R , Moser U , Mutschler E , Lambrecht G , Herawi M
Ref : Digestive Diseases & Sciences , 35 :1468 , 1990
PubMedID: 2253531

Title : Muscarinic receptors mediating acid secretion in isolated rat gastric parietal cells are of M3 type - Pfeiffer_1990_Gastroenterology_98_218
Author(s) : Pfeiffer A , Rochlitz H , Noelke B , Tacke R , Moser U , Mutschler E , Lambrecht G
Ref : Gastroenterology , 98 :218 , 1990
PubMedID: 2293581

Title : Muscarinic receptor subtypes in rat pancreatic islets: binding and functional studies - Verspohl_1990_Eur.J.Pharmacol_178_303
Author(s) : Verspohl EJ , Tacke R , Mutschler E , Lambrecht G
Ref : European Journal of Pharmacology , 178 :303 , 1990
PubMedID: 2187704

Title : Selective antagonists provide evidence that M1 muscarinic receptors may mediate carbachol-induced drinking in the rat - Polidori_1990_Eur.J.Pharmacol_179_159
Author(s) : Polidori C , Massi M , Lambrecht G , Mutschler E , Tacke R , Melchiorre C
Ref : European Journal of Pharmacology , 179 :159 , 1990
PubMedID: 2364977

Title : Cyproheptadine displays high affinity for muscarinic receptors but does not discriminate between receptor subtypes - Eltze_1989_Eur.J.Pharmacol_173_219
Author(s) : Eltze M , Lambrecht G , Mutschler E
Ref : European Journal of Pharmacology , 173 :219 , 1989
PubMedID: 2625138

Title : Pharmacology of hexahydro-difenidol, hexahydro-sila-difenidol and related selective muscarinic antagonists - Lambrecht_1989_Trends.Pharmacol.Sci_Suppl_60
Author(s) : Lambrecht G , Feifel R , Moser U , Wagner-Roder M , Choo LK , Camus J , Tastenoy M , Waelbroeck M , Strohmann C , Tacke R
Ref : Trends in Pharmacological Sciences , Suppl :60 , 1989
PubMedID: 2694525

Title : Poster: M1-Potencies of muscarinic agonists in rabbit isolated vas deferens -
Author(s) : Jokisch-Mehrling B , Feifel R , Eltze M , Rodrigues de Miranda JF , Lambrecht G , Mutschler E
Ref : Trends in Pharmacological Sciences , Suppl :109 , 1989
PubMedID:

Title : Poster: [3H]-(+\/-}-Telenzepine selectively labels muscarinic M1-receptors in calf superior cervical ganglia -
Author(s) : Feifel R , Rodrigues de Miranda JF , Strohmann C , Tacke R , Lambrecht G , Mutschler E
Ref : Trends in Pharmacological Sciences , Suppl :110 , 1989
PubMedID:

Title : Structure-activity relationships of new analogues of arecaidine propargyl ester at muscarinic M1 and M2 receptor subtypes - Moser_1989_Br.J.Pharmacol_96_319
Author(s) : Moser U , Lambrecht G , Wagner M , Wess J , Mutschler E
Ref : British Journal of Pharmacology , 96 :319 , 1989
PubMedID: 2924082

Title : Poster: Antimuscarinic potencies of olefinic analogues related to hexahydro-difenidol at three muscarinic receptor subtypes -
Author(s) : Choo LK , Wagner M , Unterhalt B , Middelberg C , Tacke R , Strohmann C , Tafel A , Mutschler E , Lambrecht G
Ref : Trends in Pharmacological Sciences , Suppl :113 , 1989
PubMedID:

Title : Poster: Pharmacophore model for antimuscarinic agents related to difenidol and siladifenidol - a molecular modeling study -
Author(s) : Bruggmann J , Holtje HD , Mutschler E , Lambrecht G , Tacke R
Ref : Trends in Pharmacological Sciences , Suppl :114 , 1989
PubMedID:

Title : Binding and functional properties of antimuscarinics of the hexocyclium\/sila-hexocyclium and hexahydro-diphenidol\/hexahydro-sila-diphenidol type to muscarinic receptor subtypes - Waelbroeck_1989_Br.J.Pharmacol_98_197
Author(s) : Waelbroeck M , Tastenoy M , Camus J , Christophe J , Strohmann C , Linoh H , Zilch H , Tacke R , Mutschler E , Lambrecht G
Ref : British Journal of Pharmacology , 98 :197 , 1989
PubMedID: 2804545

Title : Stereoselectivity at muscarinic receptor subtypes: observations with the enantiomers of phenglutarimide - Lambrecht_1989_Chirality_1_170
Author(s) : Lambrecht G , Feifel R , Mutschler E
Ref : Chirality , 1 :170 , 1989
PubMedID: 2642045

Title : Affinity profiles of hexahydro-sila-difenidol analogues at muscarinic receptor subtypes - Lambrecht_1989_Eur.J.Pharmacol_168_71
Author(s) : Lambrecht G , Feifel R , Wagner-Roder M , Strohmann C , Zilch H , Tacke R , Waelbroeck M , Christophe J , Boddeke HW , Mutschler E
Ref : European Journal of Pharmacology , 168 :71 , 1989
PubMedID: 2583233

Title : Effect of M2 muscarinic receptor antagonist 4-DAMP, on prostaglandin synthesis and mechanical function in the isolated rabbit heart - Jaiswal_1989_Gen.Pharmacol_20_497
Author(s) : Jaiswal N , Lambrecht G , Mutschler E , Malik KU
Ref : General Pharmacology , 20 :497 , 1989
PubMedID: 2753346

Title : Different muscarine receptors mediate the prejunctional inhibition of [3H]-noradrenaline release in rat or guinea-pig iris and the contraction of the rabbit iris sphincter muscle - Fuder_1989_Naunyn.Schmiedebergs.Arch.Pharmacol_340_597
Author(s) : Fuder H , Schopf J , Unckell J , Wesner MT , Melchiorre C , Tacke R , Mutschler E , Lambrecht G
Ref : Naunyn Schmiedebergs Arch Pharmacol , 340 :597 , 1989
PubMedID: 2615852

Title : Synthesis and muscarinic activity of a series of tertiary and quaternary N-substituted guvacine esters structurally related to arecoline and arecaidine propargyl ester - Wolf-Pflugmann_1989_Arzneimittelforschung_39_539
Author(s) : Wolf-Pflugmann M , Lambrecht G , Wess J , Mutschler E
Ref : Arzneimittelforschung , 39 :539 , 1989
PubMedID: 2757669

Title : Stereoselectivity of the interaction of muscarinic antagonists with their receptors - Waelbroeck_1989_Trends.Pharmacol.Sci_Suppl_65
Author(s) : Waelbroeck M , Tastenoy M , Camus J , Feifel R , Mutschler E , Strohmann C , Tacke R , Lambrecht G , Christophe J
Ref : Trends in Pharmacological Sciences , Suppl :65 , 1989
PubMedID: 2694526

Title : Human HT-29 colon carcinoma cells contain muscarinic M3 receptors coupled to phosphoinositide metabolism - Kopp_1989_Eur.J.Pharmacol_172_397
Author(s) : Kopp R , Lambrecht G , Mutschler E , Moser U , Tacke R , Pfeiffer A
Ref : European Journal of Pharmacology , 172 :397 , 1989
PubMedID: 2555210

Title : Poster: High affinity pirenzepine receptors in chicken atria are different from Ml type -
Author(s) : Tietz H , Lindmar R , Loffelholz K , Strohmann C , Tacke R , Lambrecht G , Mutschler E
Ref : Trends in Pharmacological Sciences , Suppl :107 , 1989
PubMedID:

Title : Affinity profiles of BTM-1086 and BTM-1041 at muscarinic receptor subtypes and at H1- and alpha 1-receptors - Eltze_1989_Eur.J.Pharmacol_170_225
Author(s) : Eltze M , Boer R , Mutschler E , Lambrecht G
Ref : European Journal of Pharmacology , 170 :225 , 1989
PubMedID: 2575995

Title : Poster: Presynaptic autoreceptors in chicken heart exhibit M1 characteristics -
Author(s) : Lindmar R , Loffelholz K , Lambrecht G , Mutschler E
Ref : Trends in Pharmacological Sciences , Suppl :108 , 1989
PubMedID:

Title : Different binding properties of muscarinic M2-receptor subtypes for agonists and antagonists in porcine gastric smooth muscle and mucosa - Herawi_1988_Gastroenterology_94_630
Author(s) : Herawi M , Lambrecht G , Mutschler E , Moser U , Pfeiffer A
Ref : Gastroenterology , 94 :630 , 1988
PubMedID: 3338633

Title : p-fluoro-hexahydro-sila-difenidol: the first M2 beta-selective muscarinic antagonist -
Author(s) : Lambrecht G , Feifel R , Forth B , Strohmann C , Tacke R , Mutschler E
Ref : European Journal of Pharmacology , 152 :193 , 1988
PubMedID: 3208832

Title : Stereoselectivity of the enantiomers of trihexyphenidyl and its methiodide at muscarinic receptor subtypes - Lambrecht_1988_Eur.J.Pharmacol_155_167
Author(s) : Lambrecht G , Feifel R , Moser U , Aasen AJ , Waelbroeck M , Christophe J , Mutschler E
Ref : European Journal of Pharmacology , 155 :167 , 1988
PubMedID: 3243330

Title : o-Methoxy-sila-hexocyclium: a new quaternary M1-selective muscarinic antagonist -
Author(s) : Lambrecht G , Gmelin G , Rafeiner K , Strohmann C , Tacke R , Mutschler E
Ref : European Journal of Pharmacology , 151 :155 , 1988
PubMedID: 3416923

Title : Methoctramine selectively blocks cardiac muscarinic M2 receptors in vivo - Wess_1988_Naunyn.Schmiedebergs.Arch.Pharmacol_338_246
Author(s) : Wess J , Angeli P , Melchiorre C , Moser U , Mutschler E , Lambrecht G
Ref : Naunyn Schmiedebergs Arch Pharmacol , 338 :246 , 1988
PubMedID: 3057387

Title : Contribution of M2 alpha and M2 beta muscarinic receptors to the action of cholinergic stimuli on prostaglandin synthesis and mechanical function in the isolated rabbit heart - Jaiswal_1988_J.Pharmacol.Exp.Ther_247_104
Author(s) : Jaiswal N , Lambrecht G , Mutschler E , Malik KU
Ref : Journal of Pharmacology & Experimental Therapeutics , 247 :104 , 1988
PubMedID: 3171970

Title : Presynaptic muscarinic receptors mediating inhibition of neurogenic contractions in rabbit vas deferens are of the ganglionic M1-type - Eltz_1988_Eur.J.Pharmacol_158_233
Author(s) : Eltz M , Gmelin G , Wess J , Strohmann C , Tacke R , Mutschler E , Lambrecht G
Ref : European Journal of Pharmacology , 158 :233 , 1988
PubMedID: 2472963

Title : Binding of the S(+)- and R(-)-enantiomers of bethanechol to muscarinic receptors in jejunal smooth muscle, nasal mucosa, atrial and ventricular myocardium of the rat - Buhl_1987_Eur.J.Pharmacol_140_221
Author(s) : Buhl T , Rodrigues de Miranda JF , Beld AJ , Lambrecht G , Mutschler E
Ref : European Journal of Pharmacology , 140 :221 , 1987
PubMedID: 3666019

Title : Antimuscarinic action of methoctramine, a new cardioselective M-2 muscarinic receptor antagonist, alone and in combination with atropine and gallamine - Melchiorre_1987_Eur.J.Pharmacol_144_117
Author(s) : Melchiorre C , Angeli P , Lambrecht G , Mutschler E , Picchio MT , Wess J
Ref : European Journal of Pharmacology , 144 :117 , 1987
PubMedID: 3436364

Title : Stimulation of ganglionic muscarinic M1 receptors by a series of tertiary arecaidine and isoarecaidine esters in the pithed rat - Wess_1987_Eur.J.Pharmacol_134_61
Author(s) : Wess J , Lambrecht G , Moser U , Mutschler E
Ref : European Journal of Pharmacology , 134 :61 , 1987
PubMedID: 3556399

Title : Selective blockade in vivo of cardiac muscarinic M2 receptors by a polymethylene tetramine, BHC-9C - Wess_1987_Eur.J.Pharmacol_142_475
Author(s) : Wess J , Lambrecht G , Mutschler E , Melchiorre C , Angeli P
Ref : European Journal of Pharmacology , 142 :475 , 1987
PubMedID: 3428357

Title : Poster: Hexahydrosiladifenidol: a selective antagonist at muscarinic M2 receptor subtypes -
Author(s) : Lambrecht G , Moser U , Wess J , Riotte J , Fuder H , Kilbinger H , Milller H , Linoh H , Tacke R , Zilch H , Mutschler E
Ref : Trends in Pharmacological Sciences , Suppl :91 , 1986
PubMedID:

Title : Muscarinic ganglionic stimulants: conformationally restrained analogues related to [4-[[N-(3-chlorophenyl)carbamoyl]oxy]-2-butynyl]trimethylammonium chloride - Lambrecht_1986_J.Med.Chem_29_1309
Author(s) : Lambrecht G , Moser U , Mutschler E , Walther G , Wess J
Ref : Journal of Medicinal Chemistry , 29 :1309 , 1986
PubMedID: 3806582

Title : The effects of racemic bethanechol and its (R)- and (S)-enantiomers on pre- and postjunctional muscarine receptors in the guinea-pig ileum - Schworer_1985_Naunyn.Schmiedebergs.Arch.Pharmacol_331_307
Author(s) : Schworer H , Lambrecht G , Mutschler E , Kilbinger H
Ref : Naunyn Schmiedebergs Arch Pharmacol , 331 :307 , 1985
PubMedID: 2869412

Title : Comparison of affinities of muscarinic antagonists to pre- and postjunctional receptors in the guinea-pig ileum - Kilbinger_1984_Eur.J.Pharmacol_103_313
Author(s) : Kilbinger H , Halim S , Lambrecht G , Weiler W , Wessler I
Ref : European Journal of Pharmacology , 103 :313 , 1984
PubMedID: 6489444

Title : A comparison of the antimuscarinic effects of pirenzepine and N-methylatropine on ganglionic and vascular muscarinic receptors in the rat - Wess_1984_Life.Sci_35_553
Author(s) : Wess J , Lambrecht G , Moser U , Mutschler E
Ref : Life Sciences , 35 :553 , 1984
PubMedID: 6379356

Title : Selective muscarinic agonists and antagonists in functional tests -
Author(s) : Mutschler E , Lambrecht G
Ref : Trends in Pharmacological Sciences , Suppl :39 , 1984
PubMedID:

Title : [Structure- and conformation-activity relationships of heterocyclic acetylcholine analogues. 16. Conformational behaviour and cholinergic properties of isoarecaidine and sulfoisoarecaidine esters] - Holtje_1983_Arzneimittelforschung_33_190
Author(s) : Holtje HD , Lambrecht G , Moser U , Mutschler E
Ref : Arzneimittelforschung , 33 :190 , 1983
PubMedID: 6601954

Title : [Structure- and conformation-activity relationships of heterocyclic acetylcholine analogs, 18. Synthesis and muscarine-type activity of sulfoarecaidine and sulfoisoarecaidine esters] -
Author(s) : Moser U , Lambrecht G , Mutschler E , Sombroek J
Ref : Arch Pharm (Weinheim) , 316 :670 , 1983
PubMedID: 6625874

Title : [Structure- and conformation-activity relationships of heterocyclic acetylcholine analogs. 17. Conformational behavior and cholinergic properties of arecaidine and sulfoarecaidine esters] - Mutschler_1983_Arzneimittelforschung_33_806
Author(s) : Mutschler E , Holtje HD , Lambrecht G , Moser U
Ref : Arzneimittelforschung , 33 :806 , 1983
PubMedID: 6684432

Title : [Nicotine--pharmacokinetics and pharmacodynamics of an additive substance] -
Author(s) : Lambrecht G
Ref : Med Monatsschr Pharm , 5 :87 , 1982
PubMedID: 7070350

Title : [Structure- and conformation-activity relationship of heterocyclic acetylcholine analogs. 13. Cholinergic properties of tertiary and quaternary 4-acetoxyquinuclidines] - Lambrecht_1982_Arzneimittelforschung_32_130
Author(s) : Lambrecht G
Ref : Arzneimittelforschung , 32 :130 , 1982
PubMedID: 7199915

Title : [Structure- and conformation-activity relationships of heterocyclic acetylcholine analogues, XIV: Acetylcholine esterase and base-catalyzed hydrolysis of enantiomeric 3-acetoxyquinuclidines (author's transl)] -
Author(s) : Lambrecht G
Ref : Arch Pharm (Weinheim) , 315 :646 , 1982
PubMedID: 7115024

Title : Muscarinic effects of various isoarecaidine esters in sympathetic ganglia - Porsius_1981_J.Auton.Pharmacol_1_119
Author(s) : Porsius AJ , Wilffert B , Lambrecht G , Moser U , Mutschler E
Ref : J Auton Pharmacol , 1 :119 , 1981
PubMedID: 7338525

Title : [Structure and conformation-activity relationships of cyclic acetylcholine analogues \/ 12th communication: Synthesis and cholinergic properties of stereoisomeric 3-acetoxythiacyclohexanes (author's transl)] - Lambrecht_1981_Arzneimittelforschung_31_634
Author(s) : Lambrecht G
Ref : Arzneimittelforschung , 31 :634 , 1981
PubMedID: 6972770

Title : Structure and conformation activity relationships of heterocyclic acetylcholine analogues. X. The inhibitory effect of 3-quinuclidinyl benzilates on cardiac muscarinic receptors - Lambrecht_1980_Arzneimittelforschung_30_2113
Author(s) : Lambrecht G
Ref : Arzneimittelforschung , 30 :2113 , 1980
PubMedID: 7194070

Title : [Structure- and conformation-activity relationships of cyclic acetylcholine analogues, XI: acetylcholinesterase- and base-catalyzed hydrolysis of derivatives of 3-acetoxypiperidine and 3-acetoxythiacyclohexane (author's transl)] -
Author(s) : Lambrecht G
Ref : Arch Pharm (Weinheim) , 313 :368 , 1980
PubMedID: 7396669

Title : Dissociation constants of 4-acetoxy-piperidines and -thiacyclohexanes at the muscarinic receptor - Lambrecht_1979_Experientia_35_1212
Author(s) : Lambrecht G
Ref : Experientia , 35 :1212 , 1979
PubMedID: 488283

Title : The rate of action of cyclic ammonium and sulfonium analogues of acetylcholine - Lambrecht_1979_Experientia_35_75
Author(s) : Lambrecht G
Ref : Experientia , 35 :75 , 1979
PubMedID: 421804

Title : [Structure- and conformation-activity relationships of cyclic acetylcholine analogues, VII: Acetylcholine esterase- and base-catalyzed hydrolysis of derivatives of 4-acetoxypiperidine and 4-acetoxythiacyclohexane (author's transl)] -
Author(s) : Lambrecht G
Ref : Arch Pharm (Weinheim) , 312 :604 , 1979
PubMedID: 496581

Title : [Structure- and conformation-activity relationships of heterocyclic acetylcholine analogs. 5. The stereochemistry of cis- and trans-4-acetoxy-1-methylthioniacyclohexanes] -
Author(s) : Lambrecht G
Ref : Arch Pharm (Weinheim) , 311 :636 , 1978
PubMedID: 678076

Title : [Structure- and conformation-activity relationships of heterocyclic acetylcholine analogs. 3. The stereochemistry of cis- and trans-3-acetoxyl-l-methylthion cyclohexanes] -
Author(s) : Lambrecht G
Ref : Arch Pharm (Weinheim) , 310 :1015 , 1977
PubMedID: 610677

Title : Structure-activity relationships of cyclic acetylcholine analogues of the piperidinol and thiacyclohexanol series - Lambrecht_1976_Experientia_32_365
Author(s) : Lambrecht G
Ref : Experientia , 32 :365 , 1976
PubMedID: 1253911

Title : [Structure-activity relationships of cyclic analogs of acetylcholine] -
Author(s) : Lambrecht G
Ref : Pharmazie , 31 :209 , 1976
PubMedID: 935221

Title : Quaternary isoarecoline: a potent muscarine-like and nicotine-like acting agonist -
Author(s) : Lambrecht G , Mutschler E
Ref : Experientia , 31 :1317 , 1975
PubMedID: 1204788

Title : [Structure- and conformation-activity relationships of cyclic acetylcholine analogs of the piperidine and quinuclidine series] -
Author(s) : Lambrecht G , Mutschler E
Ref : Arzneimittelforschung , 24 :1725 , 1974
PubMedID: 4480042

Title : [Structure-activity relationships of isoarecaidine esters] -
Author(s) : Lambrecht G , Mutschler E
Ref : Arzneimittelforschung , 23 :1427 , 1973
PubMedID: 4801326