| Title : Triphenylphosphine-catalysed amide bond formation between carboxylic acids and amines - Lenstra_2014_Chem.Commun.(Camb)_50_5763 |
| Author(s) : Lenstra DC , Rutjes FP , Mecinovic J |
| Ref : Chem Commun (Camb) , 50 :5763 , 2014 |
|
Abstract :
Unactivated carboxylic acids and amines undergo organocatalytic Ph3P/CCl4-mediated amide bond formation by employing in situ reduction of triphenylphosphine oxide to triphenylphosphine in the presence of diethoxymethylsilane and bis(4-nitrophenyl)phosphate. |
| PubMedSearch : Lenstra_2014_Chem.Commun.(Camb)_50_5763 |
| PubMedID: 24752820 |
| Substrate | N-benzyl-picolinamide |
Lenstra DC, Rutjes FP, Mecinovic J (2014)
Triphenylphosphine-catalysed amide bond formation between carboxylic acids and amines
Chem Commun (Camb)
50 :5763
Lenstra DC, Rutjes FP, Mecinovic J (2014)
Chem Commun (Camb)
50 :5763