| Title : Microbial gatekeepers: unraveling the role of the gut microbiota enzyme DPP4 in diabetes management - Liao_2023_Trends.Biochem.Sci__ |
| Author(s) : Liao L , Lin F , Gao J |
| Ref : Trends in Biochemical Sciences , : , 2023 |
|
Abstract :
Wang et al. identified dipeptidyl peptidase 4 (DPP4) as a gut microbe-derived enzyme that impacts on host glucose metabolism. They further introduced a novel therapeutic, daurisoline-d4 (Dau-d4), a selective microbial DPP4 (mDPP4) inhibitor that shows promise in improving glucose tolerance, highlighting the potential of therapies that target both host enzymes and gut microbial enzymes. |
| PubMedSearch : Liao_2023_Trends.Biochem.Sci__ |
| PubMedID: 37770288 |
| Inhibitor | O-Methyl-Dauracine |
Liao L, Lin F, Gao J (2023)
Microbial gatekeepers: unraveling the role of the gut microbiota enzyme DPP4 in diabetes management
Trends in Biochemical Sciences
:
Liao L, Lin F, Gao J (2023)
Trends in Biochemical Sciences
: