| Title : Markedly enhancing lipase-catalyzed synthesis of nucleoside drugs' ester by using a mixture system containing organic solvents and ionic liquid - Liu_2006_Bioorg.Med.Chem.Lett_16_3769 |
| Author(s) : Liu BK , Wang N , Chen ZC , Wu Q , Lin XF |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :3769 , 2006 |
|
Abstract :
Eightfold higher yields and three times faster reaction rates were achieved by means of using a mixture solvent system composed of 90% acetone and 10% [BMIM]BF4 in the lipase-catalyzed regioselective synthesis of polymerizable ester of nucleoside drugs. |
| PubMedSearch : Liu_2006_Bioorg.Med.Chem.Lett_16_3769 |
| PubMedID: 16682199 |
Liu BK, Wang N, Chen ZC, Wu Q, Lin XF (2006)
Markedly enhancing lipase-catalyzed synthesis of nucleoside drugs' ester by using a mixture system containing organic solvents and ionic liquid
Bioorganic & Medicinal Chemistry Lett
16 :3769
Liu BK, Wang N, Chen ZC, Wu Q, Lin XF (2006)
Bioorganic & Medicinal Chemistry Lett
16 :3769