| Title : Neurotoxicity of organophosphorus pesticides: predictions can be based on in vitro studies with hen and human enzymes - Lotti_1978_Arch.Toxicol_41_215 |
| Author(s) : Lotti M , Johnson MK |
| Ref : Archives of Toxicology , 41 :215 , 1978 |
|
Abstract :
The comparative inhibitory power of organophosphorus esters in vitro against hen brain acetylcholinesterase and neurotoxic esterase correlates with their comparative effects (death or delayed neuropathy) in vivo. Further comparisons of the in vitro effects seen with hen and human enzymes facilitates extrapolations to the human in vivo situation. |
| PubMedSearch : Lotti_1978_Arch.Toxicol_41_215 |
| PubMedID: 736792 |
Lotti M, Johnson MK (1978)
Neurotoxicity of organophosphorus pesticides: predictions can be based on in vitro studies with hen and human enzymes
Archives of Toxicology
41 :215
Lotti M, Johnson MK (1978)
Archives of Toxicology
41 :215