| Title : Structure of the glycosyl-phosphatidylinositol membrane anchor of acetylcholinesterase from the electric organ of the electric-fish, Torpedo californica - Mehlert_1993_Biochem.J_296_473 |
| Author(s) : Mehlert A , Varon L , Silman I , Homans SW , Ferguson MA |
| Ref : Biochemical Journal , 296 :473 , 1993 |
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Abstract :
The structure of the glycan moiety of the glycosyl-phosphatidylinositol (GPI) membrane anchor from Torpedo californica (electric fish) electric-organ acetylcholinesterase was solved using n.m.r., methylation analysis and chemical and enzymic micro-sequencing. Two structures were found to be present: Glc alpha 1-2Man alpha 1-2Man alpha 1-6Man alpha 1-4GlcN alpha 1-6myo-inositol and Glc alpha 1-2Man alpha 1-2Man alpha 1-6(GalNAc beta 1-4)Man alpha 1-4GlcN alpha 1-6myo-inositol. The presence of glucose in this GPI anchor structure is a novel feature. The anchor was also shown to contain 2.3 residues of ethanolamine per molecule. |
| PubMedSearch : Mehlert_1993_Biochem.J_296_473 |
| PubMedID: 8257440 |
Mehlert A, Varon L, Silman I, Homans SW, Ferguson MA (1993)
Structure of the glycosyl-phosphatidylinositol membrane anchor of acetylcholinesterase from the electric organ of the electric-fish, Torpedo californica
Biochemical Journal
296 :473
Mehlert A, Varon L, Silman I, Homans SW, Ferguson MA (1993)
Biochemical Journal
296 :473