| Title : Lipoprotein lipase: genetics, lipid uptake, and regulation - Merkel_2002_J.Lipid.Res_43_1997 |
| Author(s) : Merkel M , Eckel RH , Goldberg IJ |
| Ref : J Lipid Res , 43 :1997 , 2002 |
|
Abstract :
Lipoprotein lipase (LPL) regulates the plasma levels of triglyceride and HDL. Three aspects are reviewed. 1) Clinical implications of human LPL gene variations: common mutations and their effects on plasma lipids and coronary heart disease are discussed. 2) LPL actions in the nervous system, liver, and heart: the discussion focuses on LPL and tissue lipid uptake. 3) LPL gene regulation: the LPL promoter and its regulatory elements are described. |
| PubMedSearch : Merkel_2002_J.Lipid.Res_43_1997 |
| PubMedID: 12454259 |
| Gene_locus related to this paper: human-LPL |
| Mutation | A125T_human-LPL |
| Gene_locus | human-LPL |
| Disease | Hyperlipoproteinemia TypeI |
Merkel M, Eckel RH, Goldberg IJ (2002)
Lipoprotein lipase: genetics, lipid uptake, and regulation
J Lipid Res
43 :1997
Merkel M, Eckel RH, Goldberg IJ (2002)
J Lipid Res
43 :1997