Mirakhur_1995_Acta.Anaesthesiol.Scand.Suppl_106_62

Reference

Title : Spontaneous recovery or evoked reversal of neuromuscular block - Mirakhur_1995_Acta.Anaesthesiol.Scand.Suppl_106_62
Author(s) : Mirakhur RK
Ref : Acta Anaesthesiologica Scandinavica Supplementum , 106 :62 , 1995
Abstract :

Recovery from the effects of muscle relaxants can occur either spontaneously by their metabolism in the body or by elimination via the normal excretion pathways, or by the administration of pharmacologic antagonists. The decision as to whether spontaneous recovery should be allowed to take place or pharmacologic reversal should be induced depends upon several factors, principal among them being the duration of action of the muscle relaxant used, its dose, and the time that is available. The recovery times of most relaxants, including atracurium and vecuronium, are such as to require antagonism if adequate recovery is to be attained quickly. An agent such as mivacurium may, however, allow complete spontaneous recovery to take place without the use of antagonists.

PubMedSearch : Mirakhur_1995_Acta.Anaesthesiol.Scand.Suppl_106_62
PubMedID: 8533549

Related information

Inhibitor Atracurium    Mivacurium    Vecuronium
Substrate Mivacurium

Citations formats

Mirakhur RK (1995)
Spontaneous recovery or evoked reversal of neuromuscular block
Acta Anaesthesiologica Scandinavica Supplementum 106 :62

Mirakhur RK (1995)
Acta Anaesthesiologica Scandinavica Supplementum 106 :62