| Title : Cholinesterase-inhibitory diterpenoids and chemical constituents from aerial parts of Caryopteris mongolica - Murata_2015_J.Nat.Med_69_471 |
| Author(s) : Murata T , Selenge E , Oikawa S , Ageishi K , Batkhuu J , Sasaki K , Yoshizaki F |
| Ref : J Nat Med , 69 :471 , 2015 |
| Abstract : A diterpenoid diglucoside (12,19-di-O-beta-D-glucopyranosyl-11-hydroxyabieta-8,11,13-triene-19-one), isoscutellarein 7-O-[beta-D-xylopyranosyl-(1-->2)]-beta-D-glucopyranoside, isoscutellarein 7-O-[alpha-L-rhamnopyranosyl-(1-->2)]-beta-D-glucopyranoside, hypolaetin 7-O-[6''-O-(p-E-coumaroyl)]-beta-D-glucopyranoside, hypolaetin 7-O-[6''-O-(E-caffeoyl)]-beta-D-glucopyranoside, and 15 known compounds were isolated from aerial parts of the Mongolian medicinal plant Caryopteris mongolica. The cholinesterase-inhibitory activities of the constituents were estimated. The abietane diterpenoids (12-O-demethylcryptojaponol and 6alpha-hydroxydemethylcryptojaponol) showed potent inhibitory activity against acetylcholinesterase from human erythrocytes and electric eel, and against butyrylcholinesterase from horse serum. |
| ESTHER : Murata_2015_J.Nat.Med_69_471 |
| PubMedSearch : Murata_2015_J.Nat.Med_69_471 |
| PubMedID: 25900047 |
Murata T, Selenge E, Oikawa S, Ageishi K, Batkhuu J, Sasaki K, Yoshizaki F (2015)
Cholinesterase-inhibitory diterpenoids and chemical constituents from aerial parts of Caryopteris mongolica
J Nat Med
69 :471
Murata T, Selenge E, Oikawa S, Ageishi K, Batkhuu J, Sasaki K, Yoshizaki F (2015)
J Nat Med
69 :471