Title : Temporal deterioration of neurological symptoms and increase of serum acetylcholine receptor antibody levels after thymectomy: a case report of a cat with myasthenia gravis - Nagata_2017_J.Vet.Med.Sci_78_1893 |
Author(s) : Nagata N , Miyoshi T , Otake Y , Suzuki H , Kagawa Y , Yamagami T , Irie M |
Ref : J Vet Med Sci , 78 :1893 , 2017 |
Abstract :
Neurological signs and serum acetylcholine receptor antibody (AChR-Ab) levels before and after thymectomy were monitored in a 6-year-old male cat with acquired Myasthenia Gravis (MG) as a paraneoplastic syndrome of thymoma. Soon after surgery, the neurological symptoms relapsed, and the cholinesterase inhibitor was administered to control them. The AChR-Ab levels increased postoperatively until 90 days after surgery. This is the first report on long term measurements of serum AChR-Ab levels in a cat with MG. Although thymectomy is valuable for the removal of thymoma, it may not resolve MG symptoms, neurological signs and serum AChR-Ab levels, without medication early after surgery. Also, this case report indicates that the AChR-Ab level might be a guide to detect a deterioration of MG symptoms. |
PubMedSearch : Nagata_2017_J.Vet.Med.Sci_78_1893 |
PubMedID: 27593682 |
Nagata N, Miyoshi T, Otake Y, Suzuki H, Kagawa Y, Yamagami T, Irie M (2017)
Temporal deterioration of neurological symptoms and increase of serum acetylcholine receptor antibody levels after thymectomy: a case report of a cat with myasthenia gravis
J Vet Med Sci
78 :1893
Nagata N, Miyoshi T, Otake Y, Suzuki H, Kagawa Y, Yamagami T, Irie M (2017)
J Vet Med Sci
78 :1893