Nedkova-Bratanova_1979_Enzyme_24_281

Reference

Title : Effect of the pesticides phosalone and lindane on the activity of some dipeptidases and disaccharidases in rat intestinal mucosa - Nedkova-Bratanova_1979_Enzyme_24_281
Author(s) : Nedkova-Bratanova N , Ivanov E , Savov G , Michailova Z , Krusteva A , Petrova S
Ref : Enzyme , 24 :281 , 1979
Abstract :

The intestinal dipeptidase and disaccharidase activities were investigated in 120 male albino rats of the Wistar strain after administration of 21 mumol.kg-1 body weight phosalone, 14.8 mumol.kg-1 body weight lindane and 10.5 mumol.kg-1 body weight phosalone combined with 7.4 mumol.kg-1 body weight lindane. The dipeptidase activity under the effect of these comparatively low doses of pesticides reveals slightly to moderate changes. The activity of intestinal disaccharidases after a 90-day phosalone and lindane treatment is markedly decreased, particularly that of sucrase. The mechanism of these changes remains unknown.

PubMedSearch : Nedkova-Bratanova_1979_Enzyme_24_281
PubMedID: 92405

Related information

Inhibitor Phosalone
Substrate Lindane

Citations formats

Nedkova-Bratanova N, Ivanov E, Savov G, Michailova Z, Krusteva A, Petrova S (1979)
Effect of the pesticides phosalone and lindane on the activity of some dipeptidases and disaccharidases in rat intestinal mucosa
Enzyme 24 :281

Nedkova-Bratanova N, Ivanov E, Savov G, Michailova Z, Krusteva A, Petrova S (1979)
Enzyme 24 :281