| Title : Kinetic resolution of rac-2-pentanol catalyzed by Candida antarctica lipase B in the ionic liquid, 1-butyl-3-methylimidazolium bis[(trifluoromethyl)sulfonyl]amide - Noel_2004_Biotechnol.Lett_26_301 |
| Author(s) : Noel M , Lozano P , Vaultier M , Iborra JL |
| Ref : Biotechnol Lett , 26 :301 , 2004 |
|
Abstract :
The ionic liquid, l-butyl-3-methylimidazolium bis[(trifluoromethyl)sulfonyl]amide ([Bmim] [NTf2]), was used as a reaction medium for the kinetic resolution of rac-2-pentanol catalyzed by free Candida antarctica lipase B, using vinyl propionate at 2% (v/v) water content. The synthetic activity of lipase in [Bmim] [NTf2] was up 2.5-times greater than in hexane, and showed high enantioselectivity (ee > 99.99%). The optimal temperature and pH were 60 degrees C and 7, respectively. A decrease in water activity (aw) produced a decay in synthetic activity, and an exponential increase in selectivity. |
| PubMedSearch : Noel_2004_Biotechnol.Lett_26_301 |
| PubMedID: 15055765 |
| Gene_locus related to this paper: canar-LipB |
| Gene_locus | canar-LipB |
| Family | Canar_LipB |
Noel M, Lozano P, Vaultier M, Iborra JL (2004)
Kinetic resolution of rac-2-pentanol catalyzed by Candida antarctica lipase B in the ionic liquid, 1-butyl-3-methylimidazolium bis[(trifluoromethyl)sulfonyl]amide
Biotechnol Lett
26 :301
Noel M, Lozano P, Vaultier M, Iborra JL (2004)
Biotechnol Lett
26 :301