canar-LipB

Candida antarctica (Trichosporon oryzae) (yeast) Lipase B CALB, CALipB ,Novozyme 435

Comment

Other strains: Pseudozyma antarctica (strain T-34) (Yeast) (Candida antarctica)\; Pseudozyma aphidis DSM 70725 || \; Through structure homology this protein is close to other fungus Lipase_3 but it is far from all other sequence in ESTHER. Novozyme 435 (Novozyme-435 N435, N-435, Novozym 435 Novozym435 Novozyme435) is CAL-B immobilized onto a macroporous acrylic polymer resin (Lewatit VP OC 1600, Bayer) by Novozyme. Fermenta Biotech BEX 10000 || \; promiscuous activity 68\/96 substrates Martinez-Martinez et al. 2018

Relationship

Family : Canar_LipB

Block : L

Position in NCBI Life Tree : Candida antarctica

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Fungi N E > Dikarya N E > Basidiomycota N E > Ustilaginomycotina N E > Ustilaginomycetes N E > Ustilaginales N E > Ustilaginaceae N E > Moesziomyces N E > Moesziomyces antarcticus N E

Molecular evidence

No mutation

1LBS - Candida antarctica triacylglycerol lipase + phosphonate inhibitor 1LBT - Candida antarctica triacylglycerol lipase + T80 (ester substrate) 1TCA - Candida antarctica triacylglycerol lipase form B 1.55 Angst 1TCB - Candida antarctica triacylglycerol lipase form B 2.1 Angst 1TCC - Candida antarctica triacylglycerol lipase form B 2.5 Angst 6ISP - Structure of Candida antarctica lipase B mutant 6ISQ - Structure of Candida antarctica lipase mutant with oxided Cys-His-Asp catalytic triad 6ISR - Structure of Candida antarctica lipase mutant with Cys-His-Asp catalytic triad 4ZV7 - Crystal structure of hexagonal form of lipase B from Candida antarctica 5GV5 - Crystal structure of Candida antarctica Lipase B with active Ser105 modified with a phosphonate inhibitor 5A71 - Open and closed conformations and protonation states of Candida antarctica Lipase B: atomic resolution native 5A6V - Open and closed conformations and protonation states of Candida antarctica Lipase B: Xenon complex 3W9B - Crystal structure of Candida antarctica lipase B with anion-tag 6J1R - Crystal structure of CALB from Candida antarctica Mutant-RacidRalco Q157L\/189A 6J1Q - Crystal structure of CALB from Candida antarctica Mutant-RacidSalco W104A\/I189V 6J1P - Crystal structure of CALB from Candida antarctica Mutant-SacidRalco A281G\/A282V\/V190C 6J1S - Crystal structure of CALB from Candida antarctica Mutant-SacidSalco W104A\/I189M\/V190C\/D134L 6J1T - Crystal structure of CALB from Candida antarctica Mutant-SacidRalco A281G\/A282V\/V190C in complex with 3a 4K6G - Crystal structure of CALB from Candida antarctica 4K6H - Crystal structure of CALB mutant L278M from Candida antarctica 4K5Q - Crystal structure of CALB mutant D223G\/L278M from Candida antarctica 4K6K - Crystal structure of CALB mutant D223G from Candida antarctica 6TP8 - Substrate protein interactions in the limbus region of the catalytic site of Candida antarctica Lipase B 3ICV - Structural consequences of a circular permutation on Lipase B from Candida Antartica (3ICV replace 2R9D on 18 July 2009) 3ICW - Structure of a circular permutation on Lipase B from Candida Antartica with Bound Suicide Inhibitor (3ICW replace 2R9D on 18 July 2009)

No kinetic

No disease

Database

Sequence

Peptide

MKLLSLTGVA GVLATCVAAT PLVKRLPSGS DPAFSQPKSV LDAGLTCQGA SPSSVSKPIL LVPGTGTTGP QSFDSNWIPL STQLGYTPCW ISPPPFMLND TQVNTEYMVN AITALYAGSG NNKLPVLTWS QGGLVAQWGL TFFPSIRSKV DRLMAFAPDY KGTVLAGPLD ALAVSAPSVW QQTTGSALTT ALRNAGGLTQ IVPTTNLYSA TDEIVQPQVS NSPLDSSYLF NGKNVQAQAV CGPLFVIDHA GSLTSQFSYV VGRSALRSTT GQARSADYGI TDCNPLPAND LTPEQKVAAA ALLAPAAAAI VAGPKQNCEP DLMPYARPFA VGKRTCSGIV TP

References (94)

Title : Unraveling the Nano-Bio Interface Interactions of a Lipase Adsorbed on Gold Nanoparticles under Laser Excitation - de Barros_2024_Langmuir_40_5663
Author(s) : de Barros HR , da Silva RTP , Fernandes R , Toro-Mendoza J , Coluzza I , Temperini MLA , Cordoba de Torresi SI
Ref : Langmuir , 40 :5663 , 2024
PubMedID: 38451216
Gene_locus related to this paper: canar-LipB

Title : Facile Synthesis of Both Enantiomers of (Z)-1,5-Octadien-3-ol (Oyster Alcohol) and Its Identification from the Pacific Oyster Crassostrea gigas - Ueda_2023_J.Oleo.Sci_72_725
Author(s) : Ueda K , Yahiro K , Akakabe Y
Ref : J Oleo Sci , 72 :725 , 2023
PubMedID: 37380488
Gene_locus related to this paper: canar-LipB

Title : Effects of kosmotropic, chaotropic, and neutral salts on Candida antarctica B lipase: An analysis of the secondary structure and its hydrolytic activity on triglycerides - Del Campo_2023_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids__159380
Author(s) : Del Campo MM , Gomez-Secundino O , Camacho-Ruiz RM , Mateos Diaz JC , Santos MM , Rodriguez JA
Ref : Biochimica & Biophysica Acta Molecular & Cellular Biology Lipids , :159380 , 2023
PubMedID: 37591327
Gene_locus related to this paper: canar-LipB

Title : Mechanistic studies of a lipase unveil effect of pH on hydrolysis products of small PET modules - Swiderek_2023_Nat.Commun_14_3556
Author(s) : Swiderek K , Velasco-Lozano S , Galmes M , Olazabal I , Sardon H , Lopez-Gallego F , Moliner V
Ref : Nat Commun , 14 :3556 , 2023
PubMedID: 37321996
Gene_locus related to this paper: canar-LipB

Title : Do they make a good match? Molecular dynamics studies on CALB-catalyzed esterification of 3-phenylpropionic and cinnamic acids - Zieniuk_2023_Arch.Biochem.Biophys__109807
Author(s) : Zieniuk B , Stepniewski TM , Fabiszewska A
Ref : Archives of Biochemistry & Biophysics , :109807 , 2023
PubMedID: 37923242
Gene_locus related to this paper: canar-LipB

Title : Short-chain alcohols inactivate an immobilized industrial lipase through two different mechanisms - Mangiagalli_2022_Biotechnol.J__e2100712
Author(s) : Mangiagalli M , Ami D , de Divitiis M , Brocca S , Catelani T , Natalello A , Lotti M
Ref : Biotechnol J , :e2100712 , 2022
PubMedID: 35188703
Gene_locus related to this paper: canar-LipB

Title : Enhanced biodegradation of waste poly(ethylene terephthalate) using a reinforced plastic degrading enzyme complex - Hwang_2022_Sci.Total.Environ__156890
Author(s) : Hwang DH , Lee ME , Cho BH , Oh JW , You SK , Ko YJ , Hyeon JE , Han SO
Ref : Sci Total Environ , :156890 , 2022
PubMedID: 35753492
Gene_locus related to this paper: idesa-peth , canar-LipB

Title : Design of 2,5-furandicarboxylic based polyesters degraded in different environmental conditions: Comprehensive experimental and theoretical study - Hu_2022_J.Hazard.Mater_425_127752
Author(s) : Hu H , Li J , Luo S , Tian Y , Wang J , Zhao YL , Zhang R , Zhu J
Ref : J Hazard Mater , 425 :127752 , 2022
PubMedID: 34906869
Gene_locus related to this paper: canar-LipB

Title : Evidence for a high pK(a) of an aspartic acid residue in the active site of CALB by a fully atomistic multiscale approach - Capone_2022_J.Biomol.Struct.Dyn__1
Author(s) : Capone M , Zanetti-Polzi L , Leonzi I , Spreti N , Daidone I
Ref : J Biomol Struct Dyn , :1 , 2022
PubMedID: 35593533
Gene_locus related to this paper: canar-LipB

Title : Computational design of an amidase by combining the best electrostatic features of two promiscuous hydrolases - Galmes_2022_Chem.Sci_13_4779
Author(s) : Galmes M , Nodling AR , He K , Luk LYP , Swiderek K , Moliner V
Ref : Chem Sci , 13 :4779 , 2022
PubMedID: 35655887
Gene_locus related to this paper: bacsu-pnbae , canar-LipB

Title : Effect of the Substituent and Amino Group Position on the Lipase-Catalyzed Resolution of gamma-Amino Esters: A Molecular Docking Study Shedding Light on Candida antarctica lipase B Enantioselectivity - Ortega-Rojas_2021_European.J.Org.Chem_2021_4790?
Author(s) : Ortega-Rojas MA , Castillo E , Razo-Hernandez RS , Pastor N , Juaristi E , Escalante J
Ref : European J Org Chem , 2021 :4790 , 2021
PubMedID:
Gene_locus related to this paper: canar-LipB

Title : From Waste to ValueDirect Utilization of alpha-Angelica Lactone as a Nonconventional Irreversible Acylating Agent in a Chromatography-Free Lipase-Catalyzed KR Approach toward sec-Alcohols - Poterala_2021_ACS.Sustain.Chem.Eng_9_10276
Author(s) : Poterala M , Borowiecki P
Ref : ACS Sustain Chem Eng , 9 :10276 , 2021
PubMedID:
Gene_locus related to this paper: canar-LipB

Title : Finite-temperature effect in the O-acylation of (R,S)-propranolol catalyzed by Candida antarctica lipase B - Valderrama_2021_J.Mol.Graph.Model_107_107951
Author(s) : Valderrama DIB , Daza MC , Doerr M
Ref : J Mol Graph Model , 107 :107951 , 2021
PubMedID: 34111759
Gene_locus related to this paper: canar-LipB

Title : Perspectives on the Role of Enzymatic Biocatalysis for the Degradation of Plastic PET - Magalhaes_2021_Int.J.Mol.Sci_22_11257
Author(s) : Magalhaes RP , Cunha JM , Sousa SF
Ref : Int J Mol Sci , 22 :11257 , 2021
PubMedID: 34681915
Gene_locus related to this paper: 9entr-EsEstB , 9bact-a0a2h5z9r5 , 9psed-peh , 9actn-h6wx58 , idesa-mheth , idesa-peth , thecd-d1a2h1 , humin-cut , 9acto-d4q9n1 , 9acto-f7ix06 , 9bact-g9by57 , bacsu-lip , bacsu-pnbae , canar-LipB , thela-m4tp71 , psemy-a4y035 , thefu-1831 , thefu-q6a0i4 , strsw-c9zcr8 , fusox-CUT , sacvd-c7mve8

Title : Combined Theoretical and Experimental Study to Unravel the Differences in Promiscuous Amidase Activity of Two Nonhomologous Enzymes - Galmes_2021_ACS.Catal_11_8635
Author(s) : Galmes M , Nodling AR , Luk L , Swiderek K , Moliner V
Ref : ACS Catal , 11 :8635 , 2021
PubMedID: 35875595
Gene_locus related to this paper: bacsu-pnbae , canar-LipB

Title : Effect of the acyl-group length on the chemoselectivity of the lipase-catalyzed acylation of propranolol-a computational study - Doerr_2021_J.Mol.Model_27_198
Author(s) : Doerr M , Romero A , Daza MC
Ref : J Mol Model , 27 :198 , 2021
PubMedID: 34115202
Gene_locus related to this paper: canar-LipB

Title : Synthesis of lipophilic arbutin ester by enzymatic transesterification in high pressure carbon dioxide - Liu_2021_Enzyme.Microb.Technol_148_109818
Author(s) : Liu KJ
Ref : Enzyme Microb Technol , 148 :109818 , 2021
PubMedID: 34116761
Gene_locus related to this paper: canar-LipB

Title : Enzymatic Polycondensation of 1,6-Hexanediol and Diethyl Adipate: A Statistical Approach Predicting the Key-Parameters in Solution and in Bulk - Nasr_2020_Polymers.(Basel)_12_
Author(s) : Nasr K , Meimoun J , Favrelle-Huret A , Winter J , Raquez JM , Zinck P
Ref : Polymers (Basel) , 12 : , 2020
PubMedID: 32847050
Gene_locus related to this paper: canar-LipB

Title : Exploring the Origin of Amidase Substrate Promiscuity in CALB by a Computational Approach - Galmes_2020_ACS.Catal_10_1938
Author(s) : Galmes MA , Garcia-Junceda E , Swiderek K , Moliner V
Ref : ACS Catal , 10 :1938 , 2020
PubMedID:
Gene_locus related to this paper: canar-LipB

Title : Principles of lipid-enzyme interactions in the limbus region of the catalytic site of Candida antarctica Lipase B - Silvestrini_2020_Int.J.Biol.Macromol_158_358
Author(s) : Silvestrini L , Cianci M
Ref : Int J Biol Macromol , 158 :358 , 2020
PubMedID: 32380114
Gene_locus related to this paper: canar-LipB

Title : Lipase-Catalyzed Reactive Extrusion: Copolymerization of sigma-Caprolactone and w-Pentadecalactone - Li_2020_Macromol.Rapid.Commun_41_e2000417
Author(s) : Li C , Xu W , Lu Y , Gross RA
Ref : Macromol Rapid Commun , 41 :e2000417 , 2020
PubMedID: 33047442
Gene_locus related to this paper: canar-LipB

Title : Cutinases as stereoselective catalysts: Specific activity and enantioselectivity of cutinases and lipases for menthol and its analogs - Su_2020_Enzyme.Microb.Technol_133_109467
Author(s) : Su A , Kiokekli S , Naviwala M , Shirke AN , Pavlidis IV , Gross RA
Ref : Enzyme Microb Technol , 133 :109467 , 2020
PubMedID: 31874689
Gene_locus related to this paper: humin-cut , canar-LipB , humla-1lipa , rhimi-lipas

Title : Global and Kinetic Profiles of Substrate Diffusion in Candida antarctica Lipase B: Molecular Dynamics with the Markov-State Model - Lu_2020_ACS.Omega_5_9806
Author(s) : Lu C , Peng X , Lu D , Liu Z
Ref : ACS Omega , 5 :9806 , 2020
PubMedID: 32391467
Gene_locus related to this paper: canar-LipB

Title : Biocatalyst CAL-B catalyzed synthesis of modified nucleosides: An overview - Kumar_2019_Synth.Commun_49_1659
Author(s) : Rajesh Kumar , Vijay Kumar , Divya Mathur , Ram Kumar , Arbind Kumar , Prasad AK
Ref : Synth Syst Biotechnol , 49 :1659 , 2019
PubMedID:
Gene_locus related to this paper: canar-LipB

Title : Stereodivergent Protein Engineering of a Lipase To Access All Possible Stereoisomers of Chiral Esters with Two Stereocenters - Xu_2019_J.Am.Chem.Soc_141_7934
Author(s) : Xu J , Cen Y , Singh W , Fan J , Wu L , Lin X , Zhou J , Huang M , Reetz MT , Wu Q
Ref : Journal of the American Chemical Society , 141 :7934 , 2019
PubMedID: 31023008
Gene_locus related to this paper: canar-LipB

Title : Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution - Cen_2019_Nat.Commun_10_3198
Author(s) : Cen Y , Singh W , Arkin M , Moody TS , Huang M , Zhou J , Wu Q , Reetz MT
Ref : Nat Commun , 10 :3198 , 2019
PubMedID: 31324776
Gene_locus related to this paper: canar-LipB

Title : Kinetics and thermodynamics of lipase catalysed synthesis of propyl caprate - Parikh_2019_Biotechnol.Lett_41_1163
Author(s) : Parikh DT , Lanjekar KJ , Rathod VK
Ref : Biotechnol Lett , 41 :1163 , 2019
PubMedID: 31463715
Gene_locus related to this paper: canar-LipB

Title : Rational enhancement of enzyme-catalyzed enantioselective reaction by construction of recombinant enzymes based on additive strategy - Han_2019_Bioprocess.Biosyst.Eng_42_1739
Author(s) : Han Y , Zhou X , Zheng L
Ref : Bioprocess Biosyst Eng , 42 :1739 , 2019
PubMedID: 31321527
Gene_locus related to this paper: canar-LipB

Title : Novozym 435: the 'perfect' lipase immobilized biocatalyst? - Ortiz_2019_Catal.Sci.Technol_9_2380
Author(s) : Ortiz C , Ferreira ML , Barbosa O , Dos Santos JCS , Rodrigues RC , Berenguer-Murcia A , Briand LE , Fernandez-Lafuente R
Ref : Catal Sci Technol , 9 :2380 , 2019
PubMedID:
Gene_locus related to this paper: canar-LipB

Title : Effect of organic solvent on enzymatic degradation of cyclic PBS-based polymers by lipase N435 - Li_2019_Int.J.Biol.Macromol_137_215
Author(s) : Li CT , Zhang M , Weng YX , Zhao D
Ref : Int J Biol Macromol , 137 :215 , 2019
PubMedID: 31255620
Gene_locus related to this paper: canar-LipB

Title : Determinants and prediction of esterase substrate promiscuity patterns - Martinez-Martinez_2018_ACS.Chem.Biol_13_225
Author(s) : Martinez-Martinez M , Coscolin C , Santiago G , Chow J , Stogios PJ , Bargiela R , Gertler C , Navarro-Fernandez J , Bollinger A , Thies S , Mendez-Garcia C , Popovic A , Brown G , Chernikova TN , Garcia-Moyano A , Bjergah GE , Perez-Garcia P , Hai T , Del Pozo MV , Stokke R , Steen IH , Cui H , Xu X , Nocek BP , Alcaide M , Distaso M , Mesa V , Pelaez AI , Sanchez J , Buchholz PCF , Pleiss J , Fernandez-Guerra A , Glockner FO , Golyshina OV , Yakimov MM , Savchenko A , Jaeger KE , Yakunin AF , Streit WR , Golyshin PN , Guallar V , Ferrer M
Ref : ACS Chemical Biology , 13 :225 , 2018
PubMedID: 29182315
Gene_locus related to this paper: 9zzzz-a0a2k8jn75 , 9zzzz-a0a2k8jt94 , 9zzzz-a0a0g3fj44 , 9zzzz-a0a0g3fh10 , 9zzzz-a0a0g3fh03 , 9bact-a0a1s5qkj8 , 9zzzz-a0a0g3feh5 , 9zzzz-a0a0g3fkz4 , 9zzzz-a0a0g3fh07 , 9zzzz-a0a0g3fh34 , 9zzzz-a0a0g3fh31 , 9bact-KY458167 , alcbs-q0vqa3 , 9bact-a0a1s5qki8 , 9zzzz-a0a0g3feq8 , 9zzzz-a0a0g3feh8 , 9zzzz-a0a0g3fh19 , 9bact-KY203037 , 9bact-a0a1s5ql22 , 9bact-a0a1s5qm34 , 9bact-KY203034 , 9bact-r9qzg0 , 9bact-a0a1s5qly8 , 9zzzz-a0a0g3fkz8 , 9zzzz-a0a0g3feg9 , 9zzzz-KY203033 , 9zzzz-a0a0g3fes4 , 9zzzz-a0a0g3fh42 , 9bact-a0a1s5qlx2 , 9zzzz-KY483651 , 9bact-a0a1s5qmh4 , 9zzzz-KY203032 , 9zzzz-EH87 , 9zzzz-a0a0g3fei1 , 9zzzz-a0a0g3fet2 , 9zzzz-KY483647 , 9zzzz-EH82 , 9zzzz-a0a0g3fe15 , 9bact-KY203031 , 9bact-t1w006 , 9zzzz-a0a0g3fet6 , 9bact-KY458164 , geoth-g8myf3 , 9bact-a0a1s5ql04 , 9gamm-a0a1y0ihk7 , 9bact-a0a1s5qly6 , 9bact-a0a1s5qkg4 , 9bact-a0a1s5qkm4 , 9gamm-s5tv80 , 9gamm-a0a0c4zhg2 , 9zzzz-t1b379 , 9gamm-KY483646 , 9bact-KY458160 , 9zzzz-a0a0g3fj57 , 9gamm-s5t8349 , 9arch-KY203036 , 9bact-KY458168 , 9zzzz-a0a0g3fes0 , 9zzzz-t1be47 , 9bact-KY458159 , 9zzzz-a0a0g3fh39 , 9bact-t1vzd5 , 9prot-EH41 , 9bact-Lip114 , alcbs-q0vt77 , 9bact-a0a1s5qke6 , 9bact-a0a1s5qkf3 , 9prot-SRP030024 , 9gamm-s5t532 , 9bact-a0a1s5qkl2 , 9bact-a0a1s5qkk8 , 9zzzz-KY203030 , 9zzzz-t1d4I7 , 9prot-KY019260 , 9bact-a0a1s5qm38 , 9arch-KY458161 , 9prot-KY010302 , 9zzzz-a0a0g3fl25 , 9actn-KY010298 , 9gamm-s5u059 , 9bact-a0a1s5qmi7 , 9bact-KY010297 , 9bact-KY483642 , 9bact-a0a1s5qkj1 , 9bact-KY010299 , 9bact-KY483648 , alcbs-q0vtl7 , 9bact-a0a1s5qf1 , 9bact-a0a1s5qkg0 , 9bact-a0a0h4tgu6 , 9bact-MilE3 , 9bact-LAE6 , 9alte-MGS-MT1 , 9bact-r9qzf7 , 9gamm-k0c6t6 , alcbs-q0vl36 , alcbs-q0vlq1 , alcbs-q0vq49 , bacsu-pnbae , canar-LipB , canan-lipasA , geost-lipas , marav-a1u5n0 , pseps-i7k8x5 , staep-GEHD , symth-q67mr3 , altma-s5cfn7 , cycsp-k0c2b8 , alcbs-q0vlk5 , 9bact-k7qe48 , 9bact-MGS-M1 , 9bact-MGS-M2 , 9bact-a0a0b5kns5 , 9zzzz-a0a0g3fej4 , 9zzzz-a0a0g3fj60 , 9zzzz-a0a0g3fej0 , 9zzzz-a0a0g3fj64 , 9bact-a0a0b5kc16 , 9zzzz-a0a0g3feg6 , 9zzzz-a0a0g3feu6

Title : Enzymatic Degradation of Poly(butylene succinate) Copolyesters Synthesized with the Use of Candida antarctica Lipase B - Wcislek_2018_Polymers.(Basel)_10_
Author(s) : Wcislek A , Sonseca Olalla A , McClain A , Piegat A , Sobolewski P , Puskas J , El Fray M
Ref : Polymers (Basel) , 10 : , 2018
PubMedID: 30966722
Gene_locus related to this paper: canar-LipB

Title : Comparison of Candida antarctica Lipase B Variants for Conversion of epsilon-Caprolactone in Aqueous Medium-Part 2 - Hock_2018_Polymers.(Basel)_10_524
Author(s) : Hock H , Engel S , Weingarten S , Keul H , Schwaneberg U , Moller M , Bocola M
Ref : Polymers (Basel) , 10 : , 2018
PubMedID: 30966558
Gene_locus related to this paper: canar-LipB

Title : Entropy connects water structure and dynamics in protein hydration layer - Dahanayake_2018_Phys.Chem.Chem.Phys_20_14765
Author(s) : Dahanayake JN , Mitchell-Koch KR
Ref : Phys Chem Chem Phys , 20 :14765 , 2018
PubMedID: 29780979
Gene_locus related to this paper: canar-LipB

Title : Stereoselectivity-Tailored, Metal-Free Hydrolytic Dynamic Kinetic Resolution of Morita-Baylis-Hillman Acetates Using an Engineered Lipase-Organic Base Cocatalyst - Xia_2017_ACS.Catal_7_4542
Author(s) : Xia B , Xu J , Xiang Z , Cen Y , Hu Y , Lin X , Wu Q
Ref : ACS Catal , 7 :4542 , 2017
PubMedID:
Gene_locus related to this paper: canar-LipB

Title : A novel self-activation mechanism of Candida antarctica lipase B - Luan_2017_Phys.Chem.Chem.Phys_19_15709
Author(s) : Luan B , Zhou R
Ref : Phys Chem Chem Phys , 19 :15709 , 2017
PubMedID: 28589990
Gene_locus related to this paper: canar-LipB

Title : Structural and Experimental Evidence for the Enantiomeric Recognition toward a Bulky sec-Alcohol by Candida antarctica Lipase B - Park_2016_ACS.Catal_6_7458
Author(s) : Park K , Kim S , Park J , Joe S , Min B , Oh J , Song J , Park SY , Park S , Lee H
Ref : , 6 :7458 , 2016
PubMedID:
Gene_locus related to this paper: canar-LipB

Title : Crystal and molecular structure of hexagonal form of lipase B from Candida antarctica - Strzelczyk_2016_Acta.Biochim.Pol_63_103
Author(s) : Strzelczyk P , Bujacz GD , Kielbasinski P , Blaszczyk J
Ref : Acta Biochim Pol , 63 :103 , 2016
PubMedID: 26716135
Gene_locus related to this paper: canar-LipB

Title : Chemo-enzymatic Baeyer-Villiger oxidation of 4-methylcyclohexanone via kinetic resolution of racemic carboxylic acids: direct access to enantioenriched lactone - Drozdz_2016_Chem.Commun.(Camb)_52_1230
Author(s) : Drozdz A , Chrobok A
Ref : Chem Commun (Camb) , 52 :1230 , 2016
PubMedID: 26612109
Gene_locus related to this paper: canar-LipB

Title : Synthesis of benzyl cinnamate by enzymatic esterification of cinnamic acid - Wang_2015_Bioresour.Technol_198_256
Author(s) : Wang Y , Zhang DH , Chen N , Zhi GY
Ref : Bioresour Technol , 198 :256 , 2015
PubMedID: 26398669
Gene_locus related to this paper: canar-LipB

Title : Combination of Novozym 435-catalyzed enantioselective hydrolysis and amidation for the preparation of optically active delta-hexadecalactone - Shimotori_2015_J.Oleo.Sci_64_561
Author(s) : Shimotori Y , Hoshi M , Miyakoshi T
Ref : J Oleo Sci , 64 :561 , 2015
PubMedID: 25948138
Gene_locus related to this paper: canar-LipB

Title : Open and closed states of Candida antarctica lipase B: protonation and the mechanism of interfacial activation - Stauch_2015_J.Lipid.Res_56_2348
Author(s) : Stauch B , Fisher SJ , Cianci M
Ref : J Lipid Res , 56 :2348 , 2015
PubMedID: 26447231
Gene_locus related to this paper: canar-LipB

Title : Interfacial Activation of Candida antarctica Lipase B: Combined Evidence from Experiment and Simulation - Zisis_2015_Biochemistry_54_5969
Author(s) : Zisis T , Freddolino PL , Turunen P , van Teeseling MC , Rowan AE , Blank KG
Ref : Biochemistry , 54 :5969 , 2015
PubMedID: 26346632
Gene_locus related to this paper: canar-LipB

Title : Lipase active site covalent anchoring of Rh(NHC) catalysts: towards chemoselective artificial metalloenzymes - Basauri-Molina_2015_Chem.Commun.(Camb)_51_6792
Author(s) : Basauri-Molina M , Riemersma CF , Wurdemann MA , Kleijn H , Klein Gebbink RJ
Ref : Chem Commun (Camb) , 51 :6792 , 2015
PubMedID: 25786894
Gene_locus related to this paper: canar-LipB , fusso-cutas

Title : First chemoenzymatic stereodivergent synthesis of both enantiomers of promethazine and ethopropazine - Borowiecki_2014_Beilstein.J.Org.Chem_10_3038
Author(s) : Borowiecki P , Paprocki D , Dranka M
Ref : Beilstein J Org Chem , 10 :3038 , 2014
PubMedID: 25670974
Gene_locus related to this paper: canar-LipB , humla-1lipa

Title : Enhanced Enzyme Kinetic Stability by Increasing Rigidity within the Active Site - Xie_2014_J.Biol.Chem_289_7994
Author(s) : Xie Y , An J , Yang G , Wu G , Zhang Y , Cui L , Feng Y
Ref : Journal of Biological Chemistry , 289 :7994 , 2014
PubMedID: 24448805
Gene_locus related to this paper: canar-LipB

Title : Theoretical Study of Primary Reaction of Pseudozyma antarctica Lipase B as the Starting Point To Understand Its Promiscuity - Swiderek_2014_ACS.Catal_4_426
Author(s) : Swiderek K , Mart S , Moliner V
Ref : ACS Catal , 4 :426 , 2014
PubMedID:
Gene_locus related to this paper: canar-LipB

Title : Exploring the Solid State Properties of Enzymatic Poly(amine-co-ester) Terpolymers to Expand their Applications in Gene Transfection - Voevodina_2014_RSC.Adv_4_8953
Author(s) : Voevodina I , Scandola M , Zhang J , Jiang Z
Ref : RSC Adv , 4 :8953 , 2014
PubMedID: 24683469
Gene_locus related to this paper: canar-LipB

Title : Candida antarctica lipase B-catalyzed reactions of beta-hydroxy esters: Competition of acylation and hydrolysis - Forro_2013_J.Mol.Catal.B.Enzym_98_92
Author(s) : Forro E , Galla Z , Fulop F
Ref : J Mol Catal B Enzym , 98 :92 , 2013
PubMedID:
Gene_locus related to this paper: canar-LipB

Title : Lipase-catalyzed enantioselective synthesis of (R,R)-lactide from alkyl lactate to produce PDLA (poly D-lactic acid) and stereocomplex PLA (poly lactic acid) - Jeon_2013_J.Biotechnol_168_201
Author(s) : Jeon BW , Lee J , Kim HS , Cho DH , Lee H , Chang R , Kim YH
Ref : J Biotechnol , 168 :201 , 2013
PubMedID: 23845270
Gene_locus related to this paper: canar-LipB

Title : Effect of molecular chaperones on the expression of Candida antarctica lipase B in Pichia pastoris - Samuel_2013_Microbiol.Res_168_615
Author(s) : Samuel P , Prasanna Vadhana AK , Kamatchi R , Antony A , Meenakshisundaram S
Ref : Microbiol Res , 168 :615 , 2013
PubMedID: 23871144
Gene_locus related to this paper: canar-LipB

Title : Genome Sequence of the Basidiomycetous Yeast Pseudozyma antarctica T-34, a Producer of the Glycolipid Biosurfactants Mannosylerythritol Lipids - Morita_2013_Genome.Announc_1_e0006413
Author(s) : Morita T , Koike H , Koyama Y , Hagiwara H , Ito E , Fukuoka T , Imura T , Machida M , Kitamoto D
Ref : Genome Announc , 1 :e0006413 , 2013
PubMedID: 23558529
Gene_locus related to this paper: canar-LipB , psea3-m9mfk8 , psea3-m9lyb4 , psea3-m9mhk2 , psea3-m9lth4 , psea3-m9mcb7 , psea3-m9lv13 , psea3-m9m1x3 , psea3-m9mf48 , psea3-m9m693 , psea3-m9mbv1 , psea3-m9lqi4

Title : Bioinformatic analysis of alpha\/beta-hydrolase fold enzymes reveals subfamily-specific positions responsible for discrimination of amidase and lipase activities - Suplatov_2012_Protein.Eng.Des.Sel_25_689
Author(s) : Suplatov DA , Besenmatter W , Svedas VK , Svendsen A
Ref : Protein Engineering Des Sel , 25 :689 , 2012
PubMedID: 23043134
Gene_locus related to this paper: canar-LipB

Title : Syntheses of enantiopure aliphatic secondary alcohols and acetates by bioresolution with lipase B from Candida antarctica - Ferreira_2012_Molecules_17_8955
Author(s) : Ferreira HV , Rocha LC , Severino RP , Porto AL
Ref : Molecules , 17 :8955 , 2012
PubMedID: 22836214
Gene_locus related to this paper: canar-LipB

Title : Covalent anchoring of a racemization catalyst to CALB-beads: towards dual immobilization of DKR catalysts - Wieczorek_2011_Tetrahedron.Lett_52_1601
Author(s) : Wieczorek B , Traff A , Krumlinde P , Dijkstra HP , Egmond MR , van Koten G , Backvall JE , Klein Gebbink RJ
Ref : Tetrahedron Letters , 52 :1601 , 2011
PubMedID:
Gene_locus related to this paper: canar-LipB , fusso-cutas

Title : Enzymatic coproduction of biodiesel and glycerol carbonate from soybean oil and dimethyl carbonate - Seong_2011_Enzyme.Microb.Technol_48_505
Author(s) : Seong PJ , Jeon BW , Lee M , Cho DH , Kim DK , Jung KS , Kim SW , Han SO , Kim YH , Park C
Ref : Enzyme Microb Technol , 48 :505 , 2011
PubMedID: 22113023
Gene_locus related to this paper: canar-LipB

Title : Lipase-catalyzed simultaneous biosynthesis of biodiesel and glycerol carbonate from corn oil in dimethyl carbonate - Min_2011_Biotechnol.Lett_33_1789
Author(s) : Min JY , Lee EY
Ref : Biotechnol Lett , 33 :1789 , 2011
PubMedID: 21516311
Gene_locus related to this paper: canar-LipB

Title : Mutant lipase-catalyzed kinetic resolution of bulky phenyl alkyl sec-alcohols: a thermodynamic analysis of enantioselectivity - Vallin_2010_Chembiochem_11_411
Author(s) : Vallin M , Syren PO , Hult K
Ref : Chembiochem , 11 :411 , 2010
PubMedID: 20049759
Gene_locus related to this paper: canar-LipB

Title : Kinetic resolution of racemic 1-phenyl 1-propanol by lipase catalyzed enantioselective esterification reaction - Karadeniz_2010_Artif.Cells.Blood.Substit.Immobil.Biotechnol_38_288
Author(s) : Karadeniz F , Bayraktar E , Mehmetoglu U
Ref : Artif Cells Blood Substit Immobil Biotechnol , 38 :288 , 2010
PubMedID: 20831353
Gene_locus related to this paper: canar-LipB

Title : Preparation of passion fruit-typical 2-alkyl ester enantiomers via lipase-catalyzed kinetic resolution - Strohalm_2010_J.Agric.Food.Chem_58_6328
Author(s) : Strohalm H , Dold S , Pendzialek K , Weiher M , Engel KH
Ref : Journal of Agricultural and Food Chemistry , 58 :6328 , 2010
PubMedID: 20415422
Gene_locus related to this paper: canar-LipB

Title : Biosynthesis of glycerol carbonate from glycerol by lipase in dimethyl carbonate as the solvent - Lee_2010_Bioprocess.Biosyst.Eng_33_1059
Author(s) : Lee KH , Park CH , Lee EY
Ref : Bioprocess Biosyst Eng , 33 :1059 , 2010
PubMedID: 20502921
Gene_locus related to this paper: canar-LipB

Title : Efficient synthesis of enantiomeric ethyl lactate by Candida antarctica lipase B (CALB)-displaying yeasts - Inaba_2009_Appl.Microbiol.Biotechnol_83_859
Author(s) : Inaba C , Maekawa K , Morisaka H , Kuroda K , Ueda M
Ref : Applied Microbiology & Biotechnology , 83 :859 , 2009
PubMedID: 19288094
Gene_locus related to this paper: canar-LipB

Title : Structural redesign of lipase B from Candida antarctica by circular permutation and incremental truncation - Qian_2009_J.Mol.Biol_393_191
Author(s) : Qian Z , Horton JR , Cheng X , Lutz S
Ref : Journal of Molecular Biology , 393 :191 , 2009
PubMedID: 19683009
Gene_locus related to this paper: canar-LipB

Title : Lipase-catalyzed esterification of (S)-naproxen ethyl ester in supercritical carbon dioxide - Kwon_2009_J.Microbiol.Biotechnol_19_1596
Author(s) : Kwon CH , Lee JH , Kim SW , Kang JW
Ref : J Microbiol Biotechnol , 19 :1596 , 2009
PubMedID: 20075625
Gene_locus related to this paper: canar-LipB

Title : Systematic comparison of HEA and HEMA as initiators in enzymatic ring-opening polymerizations - Xiao_2009_Macromol.Biosci_9_713
Author(s) : Xiao Y , Takwa M , Hult K , Koning CE , Heise A , Martinelle M
Ref : Macromol Biosci , 9 :713 , 2009
PubMedID: 19242919
Gene_locus related to this paper: canar-LipB

Title : Understanding the plasticity of the alpha\/beta hydrolase fold: lid swapping on the Candida antarctica lipase B results in chimeras with interesting biocatalytic properties - Skjot_2009_Chembiochem_10_520
Author(s) : Skjot M , De Maria L , Chatterjee R , Svendsen A , Patkar SA , Ostergaard PR , Brask J
Ref : Chembiochem , 10 :520 , 2009
PubMedID: 19156649
Gene_locus related to this paper: canar-LipB

Title : Understanding promiscuous amidase activity of an esterase from Bacillus subtilis -
Author(s) : Kourist R , Bartsch S , Fransson L , Hult K , Bornscheuer UT
Ref : Chembiochem , 9 :67 , 2008
PubMedID: 18022973
Gene_locus related to this paper: bacsu-pnbae , canar-LipB

Title : Lipase catalyzed HEMA initiated ring-opening polymerization: in situ formation of mixed polyester methacrylates by transesterification - Takwa_2008_Biomacromolecules_9_704
Author(s) : Takwa M , Xiao Y , Simpson N , Malmstrom E , Hult K , Koning CE , Heise A , Martinelle M
Ref : Biomacromolecules , 9 :704 , 2008
PubMedID: 18198845
Gene_locus related to this paper: canar-LipB

Title : A genetic selection system for evolving enantioselectivity of enzymes - Reetz_2008_Chem.Commun.(Camb)__5502
Author(s) : Reetz MT , Hobenreich H , Soni P , Fernandez L
Ref : Chem Commun (Camb) , :5502 , 2008
PubMedID: 18997932
Gene_locus related to this paper: canar-LipB

Title : Candida antarctica lipase B chemically immobilized on epoxy-activated micro- and nanobeads: catalysts for polyester synthesis - Chen_2008_Biomacromolecules_9_463
Author(s) : Chen B , Hu J , Miller EM , Xie W , Cai M , Gross RA
Ref : Biomacromolecules , 9 :463 , 2008
PubMedID: 18197630
Gene_locus related to this paper: canar-LipB

Title : Lipase-mediated transformation of vegetable oils into biodiesel using propan-2-ol as acyl acceptor - Modi_2006_Biotechnol.Lett_28_637
Author(s) : Modi MK , Reddy JR , Rao BV , Prasad RB
Ref : Biotechnol Lett , 28 :637 , 2006
PubMedID: 16642301
Gene_locus related to this paper: canar-LipB

Title : Biocatalytic ammonolysis of (5S)-4,5-dihydro-1H-pyrrole-1,5-dicarboxylic acid, 1-(1,1-dimethylethyl)-5-ethyl ester: preparation of an intermediate to the dipeptidyl peptidase IV inhibitor Saxagliptin - Gill_2006_Bioorg.Med.Chem.Lett_16_705
Author(s) : Gill I , Patel R
Ref : Bioorganic & Medicinal Chemistry Lett , 16 :705 , 2006
PubMedID: 16257208
Gene_locus related to this paper: canar-LipB

Title : Cocrystallization of random copolymers of omega-pentadecalactone and epsilon-caprolactone synthesized by lipase catalysis - Ceccorulli_2005_Biomacromolecules_6_902
Author(s) : Ceccorulli G , Scandola M , Kumar A , Kalra B , Gross RA
Ref : Biomacromolecules , 6 :902 , 2005
PubMedID: 15762658
Gene_locus related to this paper: canar-LipB

Title : Understanding structure-stability relationships of Candida antartica lipase B in ionic liquids - De Diego_2005_Biomacromolecules_6_1457
Author(s) : De Diego T , Lozano P , Gmouh S , Vaultier M , Iborra JL
Ref : Biomacromolecules , 6 :1457 , 2005
PubMedID: 15877365
Gene_locus related to this paper: canar-LipB

Title : An inverse substrate orientation for the regioselective acylation of 3',5'-diaminonucleosides catalyzed by Candida antarctica lipase B? - Lavandera_2005_Chembiochem_6_1381
Author(s) : Lavandera I , Fernandez S , Magdalena J , Ferrero M , Kazlauskas RJ , Gotor V
Ref : Chembiochem , 6 :1381 , 2005
PubMedID: 15977272
Gene_locus related to this paper: canar-LipB

Title : Creating space for large secondary alcohols by rational redesign of Candida antarctica lipase B - Magnusson_2005_Chembiochem_6_1051
Author(s) : Magnusson AO , Rotticci-Mulder JC , Santagostino A , Hult K
Ref : Chembiochem , 6 :1051 , 2005
PubMedID: 15883973
Gene_locus related to this paper: canar-LipB

Title : Improving the catalytic activity of Candida antarctica lipase B by circular permutation - Qian_2005_J.Am.Chem.Soc_127_13466
Author(s) : Qian Z , Lutz S
Ref : Journal of the American Chemical Society , 127 :13466 , 2005
PubMedID: 16190688
Gene_locus related to this paper: canar-LipB

Title : Synthesis of flavor and fragrance esters using Candida antarctica lipase - Larios_2004_Appl.Microbiol.Biotechnol_65_373
Author(s) : Larios A , Garcia HS , Oliart RM , Valerio-Alfaro G
Ref : Applied Microbiology & Biotechnology , 65 :373 , 2004
PubMedID: 15248036
Gene_locus related to this paper: canar-LipB

Title : Synthesis of novel D-glucuronic acid fatty esters using Candida antarctica lipase in tert-butanol - Moreau_2004_Biotechnol.Lett_26_419
Author(s) : Moreau B , Lognay GC , Blecker C , Brohee JC , Chery F , Rollin P , Paquot M , Marlier M
Ref : Biotechnol Lett , 26 :419 , 2004
PubMedID: 15104141
Gene_locus related to this paper: canar-LipB

Title : Kinetic resolution of rac-2-pentanol catalyzed by Candida antarctica lipase B in the ionic liquid, 1-butyl-3-methylimidazolium bis[(trifluoromethyl)sulfonyl]amide - Noel_2004_Biotechnol.Lett_26_301
Author(s) : Noel M , Lozano P , Vaultier M , Iborra JL
Ref : Biotechnol Lett , 26 :301 , 2004
PubMedID: 15055765
Gene_locus related to this paper: canar-LipB

Title : Regioselective acylation of flavonoids catalyzed by immobilized Candida antarctica lipase under reduced pressure - Passicos_2004_Biotechnol.Lett_26_1073
Author(s) : Passicos E , Santarelli X , Coulon D
Ref : Biotechnol Lett , 26 :1073 , 2004
PubMedID: 15218382
Gene_locus related to this paper: canar-LipB

Title : Stability improvement of immobilized Candida antarctica lipase B in an organic medium under microwave radiation - Rejasse_2004_Org.Biomol.Chem_2_1086
Author(s) : Rejasse B , Lamare S , Legoy MD , Besson T
Ref : Org Biomol Chem , 2 :1086 , 2004
PubMedID: 15034633
Gene_locus related to this paper: canar-LipB

Title : Lipase catalysed resolution of the Lotrafiban intermediate 2,3,4,5-tetrahydro-4-methyl-3-oxo-1 H-1,4-benzodiazepine-2-acetic acid methyl ester in ionic liquids: comparison to the industrial t-butanol process - Roberts_2004_Green.Chem_6_475
Author(s) : Roberts NJ , Seago A , Carey JS , Freer R , Preston C , Lye GJ
Ref : Green Chem , 6 :475 , 2004
PubMedID:
Gene_locus related to this paper: canar-LipB

Title : Fluorophoric assay for the high-throughput determination of amidase activity - Henke_2003_Anal.Chem_75_255
Author(s) : Henke E , Bornscheuer UT
Ref : Analytical Chemistry , 75 :255 , 2003
PubMedID: 12553759
Gene_locus related to this paper: canar-LipB

Title : Water activity effects on geranyl acetate synthesis catalyzed by novozym in supercritical ethane and in supercritical carbon dioxide - Peres_2003_J.Agric.Food.Chem_51_1884
Author(s) : Peres C , Gomes da Silva MD , Barreiros S
Ref : Journal of Agricultural and Food Chemistry , 51 :1884 , 2003
PubMedID: 12643646
Gene_locus related to this paper: canar-LipB

Title : Regeneration of immobilized Candida antarctica lipase for transesterification - Chen_2003_J.Biosci.Bioeng_95_466
Author(s) : Chen JW , Wu WT
Ref : J Biosci Bioeng , 95 :466 , 2003
PubMedID: 16233441
Gene_locus related to this paper: canar-LipB

Title : Regiospecific analysis by ethanolysis of oil with immobilized Candida antarctica lipase - Shimada_2003_Lipids_38_1281
Author(s) : Shimada Y , Ogawa J , Watanabe Y , Nagao T , Kawashima A , Kobayashi T , Shimizu S
Ref : Lipids , 38 :1281 , 2003
PubMedID: 14870932
Gene_locus related to this paper: canar-LipB

Title : Improving tolerance of Candida antarctica lipase B towards irreversible thermal inactivation through directed evolution - Zhang_2003_Protein.Eng_16_599
Author(s) : Zhang N , Suen WC , Windsor W , Xiao L , Madison V , Zaks A
Ref : Protein Engineering , 16 :599 , 2003
PubMedID: 12968077
Gene_locus related to this paper: canar-LipB

Title : Ethyl esterification of docosahexaenoic acid in an organic solvent-free system with immobilized Candida antarctica lipase - Shimada_2001_J.Biosci.Bioeng_92_19
Author(s) : Shimada Y , Watanabe Y , Sugihara A , Baba T , Ooguri T , Moriyama S , Terai T , Tominaga Y
Ref : J Biosci Bioeng , 92 :19 , 2001
PubMedID: 16233051
Gene_locus related to this paper: canar-LipB

Title : Pretreatment of immobilized Candida antarctica lipase for biodiesel fuel production from plant oil - Samukawa_2000_J.Biosci.Bioeng_90_180
Author(s) : Samukawa T , Kaieda M , Matsumoto T , Ban K , Kondo A , Shimada Y , Noda H , Fukuda H
Ref : J Biosci Bioeng , 90 :180 , 2000
PubMedID: 16232839
Gene_locus related to this paper: canar-LipB

Title : Stepwise ethanolysis of tuna oil using immobilized Candida antarctica lipase - Watanabe_1999_J.Biosci.Bioeng_88_622
Author(s) : Watanabe Y , Shimada Y , Sugihara A , Tominaga Y
Ref : J Biosci Bioeng , 88 :622 , 1999
PubMedID: 16232674
Gene_locus related to this paper: canar-LipB

Title : Crystallographic and molecular-modeling studies of lipase B from Candida antarctica reveal a stereospecificity pocket for secondary alcohols - Uppenberg_1995_Biochemistry_34_16838
Author(s) : Uppenberg J , Ohrner N , Norin M , Hult K , Kleywegt GJ , Patkar S , Waagen V , Anthonsen T , Jones TA
Ref : Biochemistry , 34 :16838 , 1995
PubMedID: 8527460
Gene_locus related to this paper: canar-LipB

Title : Crystallization and preliminary X-ray studies of lipase B from Candida antarctica - Uppenberg_1994_J.Mol.Biol_235_790
Author(s) : Uppenberg J , Patkar S , Bergfors T , Jones TA
Ref : Journal of Molecular Biology , 235 :790 , 1994
PubMedID: 8289302
Gene_locus related to this paper: canar-LipB

Title : The sequence, crystal structure determination and refinement of two crystal forms of lipase B from Candida antarctica - Uppenberg_1994_Structure_2_293
Author(s) : Uppenberg J , Hansen MT , Patkar S , Jones TA
Ref : Structure , 2 :293 , 1994
PubMedID: 8087556
Gene_locus related to this paper: canar-LipB