Nomura_2016_Chem.Biol.Interact_259_211

Reference

Title : Lipases and their inhibitors in health and disease - Nomura_2016_Chem.Biol.Interact_259_211
Author(s) : Nomura DK , Casida JE
Ref : Chemico-Biological Interactions , 259 :211 , 2016
Abstract :

Lipids play diverse and important biological roles including maintaining cellular integrity, storing fat for energy, acting as signaling molecules, and forming microdomains to support membrane protein signaling. Altering the levels of specific lipid species through activating or inactivating their biosynthetic or degradative pathways has been shown to provide either therapeutic benefit or cause disease. This review focuses on the functional, therapeutic, and (patho)physiological roles of lipases within the serine hydrolase superfamily and their inhibitors, with particular emphasis on the pharmacological tools, drugs, and environmental chemicals that inhibit these lipases.

PubMedSearch : Nomura_2016_Chem.Biol.Interact_259_211
PubMedID: 27067293

Related information

Citations formats

Nomura DK, Casida JE (2016)
Lipases and their inhibitors in health and disease
Chemico-Biological Interactions 259 :211

Nomura DK, Casida JE (2016)
Chemico-Biological Interactions 259 :211