Full name : Nomura Daniel K
First name : Daniel K
Mail : Department of Chemical Physiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037
Zip Code :
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Country : USA
Email : dnomura@scripps.edu
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Comment
| Title : Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues - Wallace_2018_Nat.Chem.Biol_14_1021 |
| Author(s) : Wallace M , Green CR , Roberts LS , Lee YM , McCarville JL , Sanchez-Gurmaches J , Meurs N , Gengatharan JM , Hover JD , Phillips SA , Ciaraldi TP , Guertin DA , Cabrales P , Ayres JS , Nomura DK , Loomba R , Metallo CM |
| Ref : Nat Chemical Biology , 14 :1021 , 2018 |
| Abstract : |
| PubMedSearch : Wallace_2018_Nat.Chem.Biol_14_1021 |
| PubMedID: 30327559 |
| Gene_locus related to this paper: human-FASN |
| Title : Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance - Ruby_2017_Cell.Rep_18_636 |
| Author(s) : Ruby MA , Massart J , Hunerdosse DM , Schonke M , Correia JC , Louie SM , Ruas JL , Naslund E , Nomura DK , Zierath JR |
| Ref : Cell Rep , 18 :636 , 2017 |
| Abstract : |
| PubMedSearch : Ruby_2017_Cell.Rep_18_636 |
| PubMedID: 28099843 |
| Title : Mapping proteome-wide interactions of reactive chemicals using chemoproteomic platforms - Counihan_2016_Curr.Opin.Chem.Biol_30_68 |
| Author(s) : Counihan JL , Ford B , Nomura DK |
| Ref : Curr Opin Chemical Biology , 30 :68 , 2016 |
| Abstract : |
| PubMedSearch : Counihan_2016_Curr.Opin.Chem.Biol_30_68 |
| PubMedID: 26647369 |
| Title : Lipases and their inhibitors in health and disease - Nomura_2016_Chem.Biol.Interact_259_211 |
| Author(s) : Nomura DK , Casida JE |
| Ref : Chemico-Biological Interactions , 259 :211 , 2016 |
| Abstract : |
| PubMedSearch : Nomura_2016_Chem.Biol.Interact_259_211 |
| PubMedID: 27067293 |
| Title : Mapping Proteome-Wide Targets of Environmental Chemicals Using Reactivity-Based Chemoproteomic Platforms - Medina-Cleghorn_2015_Chem.Biol_22_1394 |
| Author(s) : Medina-Cleghorn D , Bateman LA , Ford B , Heslin A , Fisher KJ , Dalvie ED , Nomura DK |
| Ref : Chemical Biology , 22 :1394 , 2015 |
| Abstract : |
| PubMedSearch : Medina-Cleghorn_2015_Chem.Biol_22_1394 |
| PubMedID: 26496688 |
| Title : Monoacylglycerol Lipase Regulates Fever Response - Sanchez-Alavez_2015_PLoS.One_10_e0134437 |
| Author(s) : Sanchez-Alavez M , Nguyen W , Mori S , Moroncini G , Viader A , Nomura DK , Cravatt BF , Conti B |
| Ref : PLoS ONE , 10 :e0134437 , 2015 |
| Abstract : |
| PubMedSearch : Sanchez-Alavez_2015_PLoS.One_10_e0134437 |
| PubMedID: 26287872 |
| Title : Chemical genetics screening reveals KIAA1363 as a cytokine-lowering target - Hunerdosse_2014_ACS.Chem.Biol_9_2905 |
| Author(s) : Hunerdosse DM , Morris PJ , Miyamoto DK , Fisher KJ , Bateman LA , Ghazaleh JR , Zhong S , Nomura DK |
| Ref : ACS Chemical Biology , 9 :2905 , 2014 |
| Abstract : |
| PubMedSearch : Hunerdosse_2014_ACS.Chem.Biol_9_2905 |
| PubMedID: 25343321 |
| Gene_locus related to this paper: human-NCEH1 |
| Title : Monoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome - Lysenko_2014_PLoS.One_9_e114521 |
| Author(s) : Lysenko LV , Kim J , Henry C , Tyrtyshnaia A , Kohnz RA , Madamba F , Simon GM , Kleschevnikova NE , Nomura DK , Ezekowitz RA , Kleschevnikov AM |
| Ref : PLoS ONE , 9 :e114521 , 2014 |
| Abstract : |
| PubMedSearch : Lysenko_2014_PLoS.One_9_e114521 |
| PubMedID: 25474204 |
| Title : Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes - Dominguez_2014_Nat.Chem.Biol_10_113 |
| Author(s) : Dominguez E , Galmozzi A , Chang JW , Hsu KL , Pawlak J , Li W , Godio C , Thomas J , Partida D , Niessen S , O'Brien PE , Russell AP , Watt MJ , Nomura DK , Cravatt BF , Saez E |
| Ref : Nat Chemical Biology , 10 :113 , 2014 |
| Abstract : |
| PubMedSearch : Dominguez_2014_Nat.Chem.Biol_10_113 |
| PubMedID: 24362705 |
| Gene_locus related to this paper: human-CES3 , mouse-Ces1d |
| Title : Multidimensional profiling platforms reveal metabolic dysregulation caused by organophosphorus pesticides - Medina-Cleghorn_2014_ACS.Chem.Biol_9_423 |
| Author(s) : Medina-Cleghorn D , Heslin A , Morris PJ , Mulvihill MM , Nomura DK |
| Ref : ACS Chemical Biology , 9 :423 , 2014 |
| Abstract : |
| PubMedSearch : Medina-Cleghorn_2014_ACS.Chem.Biol_9_423 |
| PubMedID: 24205821 |
| Title : Organophosphorus flame retardants inhibit specific liver carboxylesterases and cause serum hypertriglyceridemia - Morris_2014_ACS.Chem.Biol_9_1097 |
| Author(s) : Morris PJ , Medina-Cleghorn D , Heslin A , King SM , Orr J , Mulvihill MM , Krauss RM , Nomura DK |
| Ref : ACS Chemical Biology , 9 :1097 , 2014 |
| Abstract : |
| PubMedSearch : Morris_2014_ACS.Chem.Biol_9_1097 |
| PubMedID: 24597639 |
| Title : Therapeutic potential of monoacylglycerol lipase inhibitors - Mulvihill_2013_Life.Sci_92_492 |
| Author(s) : Mulvihill MM , Nomura DK |
| Ref : Life Sciences , 92 :492 , 2013 |
| Abstract : |
| PubMedSearch : Mulvihill_2013_Life.Sci_92_492 |
| PubMedID: 23142242 |
| Title : Monoacylglycerol lipase controls endocannabinoid and eicosanoid signaling and hepatic injury in mice - Cao_2013_Gastroenterology_144_808 |
| Author(s) : Cao Z , Mulvihill MM , Mukhopadhyay P , Xu H , Erdelyi K , Hao E , Holovac E , Hasko G , Cravatt BF , Nomura DK , Pacher P |
| Ref : Gastroenterology , 144 :808 , 2013 |
| Abstract : |
| PubMedSearch : Cao_2013_Gastroenterology_144_808 |
| PubMedID: 23295443 |
| Gene_locus related to this paper: human-MGLL |
| Title : Inhibition of monoacylglycerol lipase attenuates nonsteroidal anti-inflammatory drug-induced gastric hemorrhages in mice - Kinsey_2011_J.Pharmacol.Exp.Ther_338_795 |
| Author(s) : Kinsey SG , Nomura DK , O'Neal ST , Long JZ , Mahadevan A , Cravatt BF , Grider JR , Lichtman AH |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 338 :795 , 2011 |
| Abstract : |
| PubMedSearch : Kinsey_2011_J.Pharmacol.Exp.Ther_338_795 |
| PubMedID: 21659471 |
| Title : A potent and selective inhibitor of KIAA1363\/AADACL1 that impairs prostate cancer pathogenesis - Chang_2011_Chem.Biol_18_476 |
| Author(s) : Chang JW , Nomura DK , Cravatt BF |
| Ref : Chemical Biology , 18 :476 , 2011 |
| Abstract : |
| PubMedSearch : Chang_2011_Chem.Biol_18_476 |
| PubMedID: 21513884 |
| Gene_locus related to this paper: human-NCEH1 |
| Title : Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors - Bachovchin_2011_Proc.Natl.Acad.Sci.U.S.A_108_6811 |
| Author(s) : Bachovchin DA , Mohr JT , Speers AE , Wang C , Berlin JM , Spicer TP , Fernandez-Vega V , Chase P , Hodder PS , Schurer SC , Nomura DK , Rosen H , Fu GC , Cravatt BF |
| Ref : Proc Natl Acad Sci U S A , 108 :6811 , 2011 |
| Abstract : |
| PubMedSearch : Bachovchin_2011_Proc.Natl.Acad.Sci.U.S.A_108_6811 |
| PubMedID: 21398589 |
| Gene_locus related to this paper: human-PPME1 |
| Title : Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation - Nomura_2011_Science_334_809 |
| Author(s) : Nomura DK , Morrison BE , Blankman JL , Long JZ , Kinsey SG , Marcondes MC , Ward AM , Hahn YK , Lichtman AH , Conti B , Cravatt BF |
| Ref : Science , 334 :809 , 2011 |
| Abstract : |
| PubMedSearch : Nomura_2011_Science_334_809 |
| PubMedID: 22021672 |
| Title : Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice - Ramesh_2011_J.Pharmacol.Exp.Ther_339_173 |
| Author(s) : Ramesh D , Ross GR , Schlosburg JE , Owens RA , Abdullah RA , Kinsey SG , Long JZ , Nomura DK , Sim-Selley LJ , Cravatt BF , Akbarali HI , Lichtman AH |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 339 :173 , 2011 |
| Abstract : |
| PubMedSearch : Ramesh_2011_J.Pharmacol.Exp.Ther_339_173 |
| PubMedID: 21719468 |
| Title : Activity-based protein profiling of organophosphorus and thiocarbamate pesticides reveals multiple serine hydrolase targets in mouse brain - Nomura_2011_J.Agric.Food.Chem_59_2808 |
| Author(s) : Nomura DK , Casida JE |
| Ref : Journal of Agricultural and Food Chemistry , 59 :2808 , 2011 |
| Abstract : |
| PubMedSearch : Nomura_2011_J.Agric.Food.Chem_59_2808 |
| PubMedID: 21341672 |
| Title : Acute overactive endocannabinoid signaling induces glucose intolerance, hepatic steatosis, and novel cannabinoid receptor 1 responsive genes - Ruby_2011_PLoS.One_6_e26415 |
| Author(s) : Ruby MA , Nomura DK , Hudak CS , Barber A , Casida JE , Krauss RM |
| Ref : PLoS ONE , 6 :e26415 , 2011 |
| Abstract : |
| PubMedSearch : Ruby_2011_PLoS.One_6_e26415 |
| PubMedID: 22073164 |
| Title : Activity-based protein profiling for biochemical pathway discovery in cancer - Nomura_2010_Nat.Rev.Cancer_10_630 |
| Author(s) : Nomura DK , Dix MM , Cravatt BF |
| Ref : Nat Rev Cancer , 10 :630 , 2010 |
| Abstract : |
| PubMedSearch : Nomura_2010_Nat.Rev.Cancer_10_630 |
| PubMedID: 20703252 |
| Title : Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis - Nomura_2010_Cell_140_49 |
| Author(s) : Nomura DK , Long JZ , Niessen S , Hoover HS , Ng SW , Cravatt BF |
| Ref : Cell , 140 :49 , 2010 |
| Abstract : |
| PubMedSearch : Nomura_2010_Cell_140_49 |
| PubMedID: 20079333 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL |
| Title : Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system - Schlosburg_2010_Nat.Neurosci_13_1113 |
| Author(s) : Schlosburg JE , Blankman JL , Long JZ , Nomura DK , Pan B , Kinsey SG , Nguyen PT , Ramesh D , Booker L , Burston JJ , Thomas EA , Selley DE , Sim-Selley LJ , Liu QS , Lichtman AH , Cravatt BF |
| Ref : Nat Neurosci , 13 :1113 , 2010 |
| Abstract : |
| PubMedSearch : Schlosburg_2010_Nat.Neurosci_13_1113 |
| PubMedID: 20729846 |
| Title : Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism - Long_2009_Chem.Biol_16_744 |
| Author(s) : Long JZ , Nomura DK , Cravatt BF |
| Ref : Chemical Biology , 16 :744 , 2009 |
| Abstract : |
| PubMedSearch : Long_2009_Chem.Biol_16_744 |
| PubMedID: 19635411 |
| Title : Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo - Long_2009_Proc.Natl.Acad.Sci.U.S.A_106_20270 |
| Author(s) : Long JZ , Nomura DK , Vann RE , Walentiny DM , Booker L , Jin X , Burston JJ , Sim-Selley LJ , Lichtman AH , Wiley JL , Cravatt BF |
| Ref : Proc Natl Acad Sci U S A , 106 :20270 , 2009 |
| Abstract : |
| PubMedSearch : Long_2009_Proc.Natl.Acad.Sci.U.S.A_106_20270 |
| PubMedID: 19918051 |
| Title : Organophosphate-sensitive lipases modulate brain lysophospholipids, ether lipids and endocannabinoids - Casida_2008_Chem.Biol.Interact_175_355 |
| Author(s) : Casida JE , Nomura DK , Vose SC , Fujioka K |
| Ref : Chemico-Biological Interactions , 175 :355 , 2008 |
| Abstract : |
| PubMedSearch : Casida_2008_Chem.Biol.Interact_175_355 |
| PubMedID: 18495101 |
| Gene_locus related to this paper: human-NCEH1 , mouse-Q8BLF1 |
| Title : Dual roles of brain serine hydrolase KIAA1363 in ether lipid metabolism and organophosphate detoxification - Nomura_2008_Toxicol.Appl.Pharmacol_228_42 |
| Author(s) : Nomura DK , Fujioka K , Issa RS , Ward AM , Cravatt BF , Casida JE |
| Ref : Toxicol Appl Pharmacol , 228 :42 , 2008 |
| Abstract : |
| PubMedSearch : Nomura_2008_Toxicol.Appl.Pharmacol_228_42 |
| PubMedID: 18164358 |
| Gene_locus related to this paper: human-NCEH1 |
| Title : Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels - Nomura_2008_Bioorg.Med.Chem.Lett_18_5875 |
| Author(s) : Nomura DK , Hudak CS , Ward AM , Burston JJ , Issa RS , Fisher KJ , Abood ME , Wiley JL , Lichtman AH , Casida JE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :5875 , 2008 |
| Abstract : |
| PubMedSearch : Nomura_2008_Bioorg.Med.Chem.Lett_18_5875 |
| PubMedID: 18752948 |
| Title : Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins - Ruby_2008_Proc.Natl.Acad.Sci.U.S.A_105_14561 |
| Author(s) : Ruby MA , Nomura DK , Hudak CS , Mangravite LM , Chiu S , Casida JE , Krauss RM |
| Ref : Proc Natl Acad Sci U S A , 105 :14561 , 2008 |
| Abstract : |
| PubMedSearch : Ruby_2008_Proc.Natl.Acad.Sci.U.S.A_105_14561 |
| PubMedID: 18794527 |
| Title : Activation of the endocannabinoid system by organophosphorus nerve agents - Nomura_2008_Nat.Chem.Biol_4_373 |
| Author(s) : Nomura DK , Blankman JL , Simon GM , Fujioka K , Issa RS , Ward AM , Cravatt BF , Casida JE |
| Ref : Nat Chemical Biology , 4 :373 , 2008 |
| Abstract : |
| PubMedSearch : Nomura_2008_Nat.Chem.Biol_4_373 |
| PubMedID: 18438404 |
| Title : Serine hydrolase KIAA1363: toxicological and structural features with emphasis on organophosphate interactions - Nomura_2006_Chem.Res.Toxicol_19_1142 |
| Author(s) : Nomura DK , Durkin KA , Chiang KP , Quistad GB , Cravatt BF , Casida JE |
| Ref : Chemical Research in Toxicology , 19 :1142 , 2006 |
| Abstract : |
| PubMedSearch : Nomura_2006_Chem.Res.Toxicol_19_1142 |
| PubMedID: 16978018 |
| Gene_locus related to this paper: human-NCEH1 , mouse-Q8BLF1 |
| Title : Each lipase has a unique sensitivity profile for organophosphorus inhibitors - Quistad_2006_Toxicol.Sci_91_166 |
| Author(s) : Quistad GB , Liang SN , Fisher KJ , Nomura DK , Casida JE |
| Ref : Toxicol Sci , 91 :166 , 2006 |
| Abstract : |
| PubMedSearch : Quistad_2006_Toxicol.Sci_91_166 |
| PubMedID: 16449251 |
| Title : A brain detoxifying enzyme for organophosphorus nerve poisons - Nomura_2005_Proc.Natl.Acad.Sci.U.S.A_102_6195 |
| Author(s) : Nomura DK , Leung D , Chiang KP , Quistad GB , Cravatt BF , Casida JE |
| Ref : Proc Natl Acad Sci U S A , 102 :6195 , 2005 |
| Abstract : |
| PubMedSearch : Nomura_2005_Proc.Natl.Acad.Sci.U.S.A_102_6195 |
| PubMedID: 15840715 |
| Gene_locus related to this paper: human-NCEH1 , mouse-Q8BLF1 |
| Title : Toxicological and structural features of organophosphorus and organosulfur cannabinoid CB1 receptor ligands - Segall_2003_Toxicol.Sci_76_131 |
| Author(s) : Segall Y , Quistad GB , Sparks SE , Nomura DK , Casida JE |
| Ref : Toxicol Sci , 76 :131 , 2003 |
| Abstract : |
| PubMedSearch : Segall_2003_Toxicol.Sci_76_131 |
| PubMedID: 12944586 |
| Title : Arachidonylsulfonyl derivatives as cannabinoid CB1 receptor and fatty acid amide hydrolase inhibitors - Segall_2003_Bioorg.Med.Chem.Lett_13_3301 |
| Author(s) : Segall Y , Quistad GB , Nomura DK , Casida JE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 13 :3301 , 2003 |
| Abstract : |
| PubMedSearch : Segall_2003_Bioorg.Med.Chem.Lett_13_3301 |
| PubMedID: 12951114 |
| Title : Selective inhibitors of fatty acid amide hydrolase relative to neuropathy target esterase and acetylcholinesterase: toxicological implications - Quistad_2002_Toxicol.Appl.Pharmacol_179_57 |
| Author(s) : Quistad GB , Sparks SE , Segall Y , Nomura DK , Casida JE |
| Ref : Toxicol Appl Pharmacol , 179 :57 , 2002 |
| Abstract : |
| PubMedSearch : Quistad_2002_Toxicol.Appl.Pharmacol_179_57 |
| PubMedID: 11884237 |
| Title : Cannabinoid CB1 receptor as a target for chlorpyrifos oxon and other organophosphorus pesticides - Quistad_2002_Toxicol.Lett_135_89 |
| Author(s) : Quistad GB , Nomura DK , Sparks SE , Segall Y , Casida JE |
| Ref : Toxicol Lett , 135 :89 , 2002 |
| Abstract : |
| PubMedSearch : Quistad_2002_Toxicol.Lett_135_89 |
| PubMedID: 12243867 |