| Title : 2-Nitrobenzylarsonium Compounds That Photorelease Heavy-Atom Cholinergic Ligands for Time-Resolved Crystallographic Studies on Cholinesterases - Peng_1998_Angew.Chem.Int.Ed.Engl_37_2691 |
| Author(s) : Peng L , Nachon F , Wirz J , Goeldner M |
| Ref : Angew Chem Int Ed Engl , 37 :2691 , 1998 |
|
Abstract :
As heavy-atom analogues of caged cholinergic ligands, the arsonium compounds 1-3 were synthesized for potential time-resolved crystallographic studies on cholinesterases. Compounds 1 and 3 possess the desired properties for dynamic studies on the catalytic mechanism of cholinesterases: structural similarity with the N-homologue, strong X-ray diffracting effect of arsenic, inhibitory effects on cholinesterases, and excellent photofragmentation kinetics. |
| PubMedSearch : Peng_1998_Angew.Chem.Int.Ed.Engl_37_2691 |
| PubMedID: 29711614 |
Peng L, Nachon F, Wirz J, Goeldner M (1998)
2-Nitrobenzylarsonium Compounds That Photorelease Heavy-Atom Cholinergic Ligands for Time-Resolved Crystallographic Studies on Cholinesterases
Angew Chem Int Ed Engl
37 :2691
Peng L, Nachon F, Wirz J, Goeldner M (1998)
Angew Chem Int Ed Engl
37 :2691