| Title : Altered glycosylation of cerebrospinal fluid butyrylcholinesterase in alzheimer's disease - Saez-Valero_2001_Brain.Res_889_247 |
| Author(s) : Saez-Valero J , Small DH |
| Ref : Brain Research , 889 :247 , 2001 |
|
Abstract :
Our previous studies have shown that a minor isoform of acetylcholinesterase (AChE) is increased in the cerebrospinal fluid (CSF) of Alzheimer's disease (AD) patients. In the present study, the glycosylation of butyrycholinesterase (BCHE) was found to be altered in AD CSF. By combining an analysis of CSF AChE and BCHE glycosylation, it is possible to identify cases of AD with more than 90% sensitivity and specificity. |
| PubMedSearch : Saez-Valero_2001_Brain.Res_889_247 |
| PubMedID: 11166713 |
Saez-Valero J, Small DH (2001)
Altered glycosylation of cerebrospinal fluid butyrylcholinesterase in alzheimer's disease
Brain Research
889 :247
Saez-Valero J, Small DH (2001)
Brain Research
889 :247