Full name : Saez-Valero Javier
First name : Javier
Mail : Instituto de Neurociencias de Alicante\; Universidad Miguel Hernandez-CSIC\; Av. Ramon y Cajal\; s\/n\; 3550 San Joan d'Alacant
Zip Code :
City :
Country : Spain
Email : j.saez@umh.es
Phone : +34965919580
Fax :
Website :
Directory :
Comment
Title : Presenilin 1 Modulates Acetylcholinesterase Trafficking and Maturation - Cortes-Gomez_2023_Int.J.Mol.Sci_24_ |
Author(s) : Cortes-Gomez M , Barbera VM , Alom J , Saez-Valero J , Garcia-Ayllon MS |
Ref : Int J Mol Sci , 24 : , 2023 |
Abstract : |
PubMedSearch : Cortes-Gomez_2023_Int.J.Mol.Sci_24_ |
PubMedID: 36674948 |
Title : Tau phosphorylation by glycogen synthase kinase 3beta modulates enzyme acetylcholinesterase expression - Cortes-Gomez_2021_J.Neurochem_157_2091 |
Author(s) : Cortes-Gomez M , Llorens-Alvarez E , Alom J , Del Ser T , Avila J , Saez-Valero J , Garcia-Ayllon MS |
Ref : Journal of Neurochemistry , 157 :2091 , 2021 |
Abstract : |
PubMedSearch : Cortes-Gomez_2021_J.Neurochem_157_2091 |
PubMedID: 32955735 |
Title : Pre-analytical stability of novel cerebrospinal fluid biomarkers - Willemse_2019_Clin.Chim.Acta_497_204 |
Author(s) : Willemse EAJ , Vermeiren Y , Garcia-Ayllon MS , Bridel C , De Deyn PP , Engelborghs S , van der Flier WM , Jansen EEW , Lopez-Font IB , Mendes V , Manadas B , de Roeck N , Saez-Valero J , Struys EA , Vanmechelen E , Andreasson U , Teunissen CE |
Ref : Clinica Chimica Acta , 497 :204 , 2019 |
Abstract : |
PubMedSearch : Willemse_2019_Clin.Chim.Acta_497_204 |
PubMedID: 31348908 |
Title : Increased Expression of Readthrough Acetylcholinesterase Variants in the Brains of Alzheimer's Disease Patients - Campanari_2016_J.Alzheimers.Dis_53_831 |
Author(s) : Campanari ML , Navarrete F , Ginsberg SD , Manzanares J , Saez-Valero J , Garcia-Ayllon MS |
Ref : J Alzheimers Dis , 53 :831 , 2016 |
Abstract : |
PubMedSearch : Campanari_2016_J.Alzheimers.Dis_53_831 |
PubMedID: 27258420 |
Title : Neuromuscular Junction Impairment in Amyotrophic Lateral Sclerosis: Reassessing the Role of Acetylcholinesterase - Campanari_2016_Front.Mol.Neurosci_9_160 |
Author(s) : Campanari ML , Garcia-Ayllon MS , Ciura S , Saez-Valero J , Kabashi E |
Ref : Front Mol Neurosci , 9 :160 , 2016 |
Abstract : |
PubMedSearch : Campanari_2016_Front.Mol.Neurosci_9_160 |
PubMedID: 28082868 |
Title : Acetylcholinesterase Modulates Presenilin-1 Levels and gamma-Secretase Activity - Campanari_2014_J.Alzheimers.Dis_41_911 |
Author(s) : Campanari ML , Garcia-Ayllon MS , Belbin O , Galceran J , Lleo A , Saez-Valero J |
Ref : J Alzheimers Dis , 41 :911 , 2014 |
Abstract : |
PubMedSearch : Campanari_2014_J.Alzheimers.Dis_41_911 |
PubMedID: 24699279 |
Title : Quantification of the Transcripts Encoding Different Forms of AChE in Various Cell Types: Real-Time PCR Coupled with Standards in Revealing the Copy Number - Bi_2014_J.Mol.Neurosci_53_461 |
Author(s) : Bi CWC , Luk WK , Campanari ML , Liu YH , Xu L , Lau KM , Xu ML , Choi RC , Saez-Valero J , Tsim KWK |
Ref : Journal of Molecular Neuroscience , 53 :461 , 2014 |
Abstract : |
PubMedSearch : Bi_2014_J.Mol.Neurosci_53_461 |
PubMedID: 24385197 |
Title : Acetylcholinesterase protein level is preserved in the Alzheimer's brain - Campanari_2014_J.Mol.Neurosci_53_446 |
Author(s) : Campanari ML , Garcia-Ayllon MS , Blazquez-Llorca L , Luk WK , Tsim KWK , Saez-Valero J |
Ref : Journal of Molecular Neuroscience , 53 :446 , 2014 |
Abstract : |
PubMedSearch : Campanari_2014_J.Mol.Neurosci_53_446 |
PubMedID: 24318838 |
Title : Presenilin-1 influences processing of the acetylcholinesterase membrane anchor PRiMA - Garcia-Ayllon_2014_Neurobiol.Aging_35_1526 |
Author(s) : Garcia-Ayllon MS , Campanari ML , Montenegro MF , Cuchillo-Ibanez I , Belbin O , Lleo A , Tsim KWK , Vidal CJ , Saez-Valero J |
Ref : Neurobiology of Aging , 35 :1526 , 2014 |
Abstract : |
PubMedSearch : Garcia-Ayllon_2014_Neurobiol.Aging_35_1526 |
PubMedID: 24612677 |
Title : CSF Presenilin-1 complexes are increased in Alzheimer's disease - Garcia-Ayllon_2013_Acta.Neuropathol.Commun_1_46 |
Author(s) : Garcia-Ayllon MS , Campanari ML , Brinkmalm G , Rabano A , Alom J , Saura CA , Andreasen N , Blennow K , Saez-Valero J |
Ref : Acta Neuropathologica Commun , 1 :46 , 2013 |
Abstract : |
PubMedSearch : Garcia-Ayllon_2013_Acta.Neuropathol.Commun_1_46 |
PubMedID: 24252417 |
Title : Readthrough acetylcholinesterase is increased in human liver cirrhosis - Garcia-Ayllon_2012_PLoS.One_7_e44598 |
Author(s) : Garcia-Ayllon MS , Millan C , Serra-Basante C , Bataller R , Saez-Valero J |
Ref : PLoS ONE , 7 :e44598 , 2012 |
Abstract : |
PubMedSearch : Garcia-Ayllon_2012_PLoS.One_7_e44598 |
PubMedID: 23028565 |
Title : Altered expression of brain acetylcholinesterase in FTDP-17 human tau transgenic mice - Silveyra_2012_Neurobiol.Aging_33_624 e23 |
Author(s) : Silveyra MX , Garcia-Ayllon MS , de Barreda EG , Small DH , Martinez S , Avila J , Saez-Valero J |
Ref : Neurobiology of Aging , 33 :624 e23 , 2012 |
Abstract : |
PubMedSearch : Silveyra_2012_Neurobiol.Aging_33_624 e23 |
PubMedID: 21530001 |
Title : Changes in acetylcholinesterase expression are associated with altered presenilin-1 levels - Silveyra_2012_Neurobiol.Aging_33_627 e27 |
Author(s) : Silveyra MX , Garcia-Ayllon MS , Serra-Basante C , Mazzoni V , Garcia-Gutierrez MS , Manzanares J , Culvenor JG , Saez-Valero J |
Ref : Neurobiology of Aging , 33 :627 e27 , 2012 |
Abstract : |
PubMedSearch : Silveyra_2012_Neurobiol.Aging_33_627 e27 |
PubMedID: 21621296 |
Title : Revisiting the Role of Acetylcholinesterase in Alzheimer's Disease: Cross-Talk with P-tau and beta-Amyloid - Garcia-Ayllon_2011_Front.Mol.Neurosci_4_22 |
Author(s) : Garcia-Ayllon MS , Small DH , Avila J , Saez-Valero J |
Ref : Front Mol Neurosci , 4 :22 , 2011 |
Abstract : |
PubMedSearch : Garcia-Ayllon_2011_Front.Mol.Neurosci_4_22 |
PubMedID: 21949503 |
Title : Altered levels of acetylcholinesterase in Alzheimer plasma - Garcia-Ayllon_2010_PLoS.One_5_e8701 |
Author(s) : Garcia-Ayllon MS , Riba-Llena I , Serra-Basante C , Alom J , Boopathy R , Saez-Valero J |
Ref : PLoS ONE , 5 :e8701 , 2010 |
Abstract : |
PubMedSearch : Garcia-Ayllon_2010_PLoS.One_5_e8701 |
PubMedID: 20090844 |
Title : Brain cholinergic impairment in liver failure - Garcia-Ayllon_2008_Brain_131_2946 |
Author(s) : Garcia-Ayllon MS , Cauli O , Silveyra MX , Rodrigo R , Candela A , Compan A , Jover R , Perez-Mateo M , Martinez S , Felipo V , Saez-Valero J |
Ref : Brain , 131 :2946 , 2008 |
Abstract : |
PubMedSearch : Garcia-Ayllon_2008_Brain_131_2946 |
PubMedID: 18772221 |
Title : Presenilin 1 interacts with acetylcholinesterase and alters its enzymatic activity and glycosylation - Silveyra_2008_Mol.Cell.Biol_28_2908 |
Author(s) : Silveyra MX , Evin G , Montenegro MF , Vidal CJ , Martinez S , Culvenor JG , Saez-Valero J |
Ref : Molecular & Cellular Biology , 28 :2908 , 2008 |
Abstract : |
PubMedSearch : Silveyra_2008_Mol.Cell.Biol_28_2908 |
PubMedID: 18299393 |
Title : Association between acetylcholinesterase and beta-amyloid peptide in Alzheimer's cerebrospinal fluid - Garcia-Ayllon_2008_Chem.Biol.Interact_175_209 |
Author(s) : Garcia-Ayllon MS , Silveyra MX , Saez-Valero J |
Ref : Chemico-Biological Interactions , 175 :209 , 2008 |
Abstract : |
PubMedSearch : Garcia-Ayllon_2008_Chem.Biol.Interact_175_209 |
PubMedID: 18554581 |
Title : Cerebrospinal fluid acetylcholinesterase changes after treatment with donepezil in patients with Alzheimer's disease - Garcia-Ayllon_2007_J.Neurochem_101_1701 |
Author(s) : Garcia-Ayllon MS , Silveyra MX , Andreasen N , Brimijoin S , Blennow K , Saez-Valero J |
Ref : Journal of Neurochemistry , 101 :1701 , 2007 |
Abstract : |
PubMedSearch : Garcia-Ayllon_2007_J.Neurochem_101_1701 |
PubMedID: 17326766 |
Title : Altered glycosylation of acetylcholinesterase in the Creutzfeldt-Jakob cerebrospinal fluid - Silveyra_2006_J.Mol.Neurosci_30_65 |
Author(s) : Silveyra MX , Garcia-Ayllon MS , Calero M , Saez-Valero J |
Ref : Journal of Molecular Neuroscience , 30 :65 , 2006 |
Abstract : |
PubMedSearch : Silveyra_2006_J.Mol.Neurosci_30_65 |
PubMedID: 17192630 |
Title : Altered glycosylation of acetylcholinesterase in Creutzfeldt-Jakob disease - Silveyra_2006_J.Neurochem_96_97 |
Author(s) : Silveyra MX , Cuadrado-Corrales N , Marcos A , Barquero MS , Rabano A , Calero M , Saez-Valero J |
Ref : Journal of Neurochemistry , 96 :97 , 2006 |
Abstract : |
PubMedSearch : Silveyra_2006_J.Neurochem_96_97 |
PubMedID: 16277609 |
Title : Changes in liver and plasma acetylcholinesterase in rats with cirrhosis induced by bile duct ligation - Garcia-Ayllon_2006_Hepatology_43_444 |
Author(s) : Garcia-Ayllon MS , Silveyra MX , Candela A , Compan A , Claria J , Jover R , Perez-Mateo M , Felipo V , Martinez S , Galceran J , Saez-Valero J |
Ref : Hepatology , 43 :444 , 2006 |
Abstract : |
PubMedSearch : Garcia-Ayllon_2006_Hepatology_43_444 |
PubMedID: 16496349 |
Title : Intraperitoneal administration of 340 kDa human plasma butyrylcholinesterase increases the level of the enzyme in the cerebrospinal fluid of rats - Saez-Valero_2005_Neurosci.Lett_383_93 |
Author(s) : Saez-Valero J , de Gracia JA , Lockridge O |
Ref : Neuroscience Letters , 383 :93 , 2005 |
Abstract : |
PubMedSearch : Saez-Valero_2005_Neurosci.Lett_383_93 |
PubMedID: 15936518 |
Title : Acetylcholinesterase level and molecular isoforms are altered in brain of Reelin Orleans mutant mice - Garcia-Ayllon_2003_J.Neurochem_87_773 |
Author(s) : Garcia-Ayllon MS , Segui D , Perales M , Lopez-Hurtado E , Prieto JJ , Saez-Valero J |
Ref : Journal of Neurochemistry , 87 :773 , 2003 |
Abstract : |
PubMedSearch : Garcia-Ayllon_2003_J.Neurochem_87_773 |
PubMedID: 14535959 |
Title : Glycosylation of acetylcholinesterase and butyrylcholinesterase changes as a function of the duration of Alzheimer's disease - Saez-Valero_2003_J.Neurosci.Res_72_520 |
Author(s) : Saez-Valero J , Fodero LR , Sjogren M , Andreasen N , Amici S , Gallai V , Vanderstichele H , Vanmechelen E , Parnetti L , Blennow K , Small DH |
Ref : Journal of Neuroscience Research , 72 :520 , 2003 |
Abstract : |
PubMedSearch : Saez-Valero_2003_J.Neurosci.Res_72_520 |
PubMedID: 12704813 |
Title : Acetylcholinesterase activation in organotypic rat hippocampal slice cultures deprived of oxygen and glucose - Saez-Valero_2003_Neurosci.Lett_348_123 |
Author(s) : Saez-Valero J , Gonzalez-Garcia C , Cena V |
Ref : Neuroscience Letters , 348 :123 , 2003 |
Abstract : |
PubMedSearch : Saez-Valero_2003_Neurosci.Lett_348_123 |
PubMedID: 12902034 |
Title : Acetylcholinesterase activity and molecular isoform distribution are altered after focal cerebral ischemia - Saez-Valero_2003_Brain.Res.Mol.Brain.Res_117_240 |
Author(s) : Saez-Valero J , Gonzalez-Garcia C , Cena V |
Ref : Brain Research Mol Brain Res , 117 :240 , 2003 |
Abstract : |
PubMedSearch : Saez-Valero_2003_Brain.Res.Mol.Brain.Res_117_240 |
PubMedID: 14559160 |
Title : Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition - Fodero_2002_J.Neurochem_81_441 |
Author(s) : Fodero LR , Saez-Valero J , McLean CA , Martins RN , Beyreuther K , Masters CL , Robertson TA , Small DH |
Ref : Journal of Neurochemistry , 81 :441 , 2002 |
Abstract : |
PubMedSearch : Fodero_2002_J.Neurochem_81_441 |
PubMedID: 12065653 |
Title : Changes in molecular isoform distribution of acetylcholinesterase in rat cortex and cerebrospinal fluid after intracerebroventricular administration of amyloid beta-peptide - Saez-Valero_2002_Neurosci.Lett_325_199 |
Author(s) : Saez-Valero J , de Ceballos ML , Small DH , de Felipe C |
Ref : Neuroscience Letters , 325 :199 , 2002 |
Abstract : |
PubMedSearch : Saez-Valero_2002_Neurosci.Lett_325_199 |
PubMedID: 12044655 |
Title : Identification of hybrid cholinesterase forms consisting of acetyl- and butyrylcholinesterase subunits in human glioma - Garcia-Ayllon_2001_Neurosci_107_199 |
Author(s) : Garcia-Ayllon MS , Saez-Valero J , Munoz-Delgado E , Vidal CJ |
Ref : Neuroscience , 107 :199 , 2001 |
Abstract : |
PubMedSearch : Garcia-Ayllon_2001_Neurosci_107_199 |
PubMedID: 11731094 |
Title : Altered glycosylation of cerebrospinal fluid butyrylcholinesterase in alzheimer's disease - Saez-Valero_2001_Brain.Res_889_247 |
Author(s) : Saez-Valero J , Small DH |
Ref : Brain Research , 889 :247 , 2001 |
Abstract : |
PubMedSearch : Saez-Valero_2001_Brain.Res_889_247 |
PubMedID: 11166713 |
Title : Acetylcholinesterase and butyrylcholinesterase glycoforms are biomarkers of Alzheimer's disease - Saez-Valero_2001_J.Alzheimers.Dis_3_323 |
Author(s) : Saez-Valero J , Small DH |
Ref : J Alzheimers Dis , 3 :323 , 2001 |
Abstract : |
PubMedSearch : Saez-Valero_2001_J.Alzheimers.Dis_3_323 |
PubMedID: 12214053 |
Title : An unusually glycosylated form of acetylcholinesterase is a CSF biomarker for Alzheimer's disease - Saez-Valero_2000_Acta.Neurol.Scand.Suppl_176_49 |
Author(s) : Saez-Valero J , Mok SS , Small DH |
Ref : Acta Neurologica Scandinavica Supplementum , 176 :49 , 2000 |
Abstract : |
PubMedSearch : Saez-Valero_2000_Acta.Neurol.Scand.Suppl_176_49 |
PubMedID: 11261805 |
Title : Altered glycosylation of acetylcholinesterase in lumbar cerebrospinal fluid of patients with Alzheimer's disease - Saez-Valero_2000_J.Neurol.Neurosurg.Psychiatry_69_664 |
Author(s) : Saez-Valero J , Barquero MS , Marcos A , McLean CA , Small DH |
Ref : Journal of Neurology Neurosurg Psychiatry , 69 :664 , 2000 |
Abstract : |
PubMedSearch : Saez-Valero_2000_J.Neurol.Neurosurg.Psychiatry_69_664 |
PubMedID: 11032625 |
Title : Characterization of molecular forms of acetyl- and butyrylcholinesterase in human acoustic neurinomas - Garcia-Ayllon_1999_Neurosci.Lett_274_56 |
Author(s) : Garcia-Ayllon MS , Saez-Valero J , Piqueras-Perez C , Vidal CJ |
Ref : Neuroscience Letters , 274 :56 , 1999 |
Abstract : |
PubMedSearch : Garcia-Ayllon_1999_Neurosci.Lett_274_56 |
PubMedID: 10530519 |
Title : Molecular isoform distribution and glycosylation of acetylcholinesterase are altered in brain and cerebrospinal fluid of patients with Alzheimer's disease - Saez-Valero_1999_J.Neurochem_72_1600 |
Author(s) : Saez-Valero J , Sberna G , McLean CA , Small DH |
Ref : Journal of Neurochemistry , 72 :1600 , 1999 |
Abstract : |
PubMedSearch : Saez-Valero_1999_J.Neurochem_72_1600 |
PubMedID: 10098867 |
Title : Inhibition of neurite outgrowth from chick sympathetic neurons by cholinesterase inhibitors is not mediated by binding to cholinesterases - Postuma_1999_Neurosci.Lett_266_77 |
Author(s) : Postuma RB , Saez-Valero J , Small DH |
Ref : Neuroscience Letters , 266 :77 , 1999 |
Abstract : |
PubMedSearch : Postuma_1999_Neurosci.Lett_266_77 |
PubMedID: 10353331 |
Title : Expression and Glycosylation of Acetylcholinesterase in Alzheimers Disease Brain - |
Author(s) : Saez-Valero J , Sberna G , McLean C , Li QX , Small DH |
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :175 , 1998 |
PubMedID: |
Title : Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the beta-amyloid protein precursor of Alzheimer's disease - Sberna_1998_J.Neurochem_71_723 |
Author(s) : Sberna G , Saez-Valero J , Li QX , Czech C , Beyreuther K , Masters CL , McLean CA , Small DH |
Ref : Journal of Neurochemistry , 71 :723 , 1998 |
Abstract : |
PubMedSearch : Sberna_1998_J.Neurochem_71_723 |
PubMedID: 9681463 |
Title : Glycosylation of acetylcholinesterase as diagnostic marker for Alzheimer's disease - |
Author(s) : Saez-Valero J , Sberna G , McLean CA , Masters CL , Small DH |
Ref : Lancet , 350 :929 , 1997 |
PubMedID: 9314873 |
Title : The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells - Sberna_1997_J.Neurochem_69_1177 |
Author(s) : Sberna G , Saez-Valero J , Beyreuther K , Masters CL , Small DH |
Ref : Journal of Neurochemistry , 69 :1177 , 1997 |
Abstract : |
PubMedSearch : Sberna_1997_J.Neurochem_69_1177 |
PubMedID: 9282941 |
Title : Biochemical properties of acetyl- and butyrylcholinesterase in human meningioma - Saez-Valero_1996_Biochim.Biophys.Acta_1317_210 |
Author(s) : Saez-Valero J , Vidal CJ |
Ref : Biochimica & Biophysica Acta , 1317 :210 , 1996 |
Abstract : |
PubMedSearch : Saez-Valero_1996_Biochim.Biophys.Acta_1317_210 |
PubMedID: 8988237 |
Title : Molecular forms of acetyl- and butyrylcholinesterase in human glioma - Saez-Valero_1996_Neurosci.Lett_206_173 |
Author(s) : Saez-Valero J , Poza-Cisneros G , Vidal CJ |
Ref : Neuroscience Letters , 206 :173 , 1996 |
Abstract : |
PubMedSearch : Saez-Valero_1996_Neurosci.Lett_206_173 |
PubMedID: 8710179 |
Title : Monomers and dimers of acetylcholinesterase in human meningioma are anchored to the membrane by glycosylphosphatidylinositol - Saez-Valero_1995_Neurosci.Lett_195_101 |
Author(s) : Saez-Valero J , Vidal CJ |
Ref : Neuroscience Letters , 195 :101 , 1995 |
Abstract : |
PubMedSearch : Saez-Valero_1995_Neurosci.Lett_195_101 |
PubMedID: 7478260 |
Title : Amphiphilic and hydrophilic forms of acetyl- and butyrylcholinesterase in human brain - Saez-Valero_1993_J.Neurosci.Res_35_678 |
Author(s) : Saez-Valero J , Tornel PL , Munoz-Delgado E , Vidal CJ |
Ref : Journal of Neuroscience Research , 35 :678 , 1993 |
Abstract : |
PubMedSearch : Saez-Valero_1993_J.Neurosci.Res_35_678 |
PubMedID: 8411269 |
Title : Ricinus communis agglutinin I reacting and non-reacting butyrylcholinesterase in human cerebrospinal fluid - Tornel_1992_Neurosci.Lett_145_59 |
Author(s) : Tornel PL , Saez-Valero J , Vidal CJ |
Ref : Neuroscience Letters , 145 :59 , 1992 |
Abstract : |
PubMedSearch : Tornel_1992_Neurosci.Lett_145_59 |
PubMedID: 1461569 |