| Title : Acetylcholinesterase activation in organotypic rat hippocampal slice cultures deprived of oxygen and glucose - Saez-Valero_2003_Neurosci.Lett_348_123 |
| Author(s) : Saez-Valero J , Gonzalez-Garcia C , Cena V |
| Ref : Neuroscience Letters , 348 :123 , 2003 |
|
Abstract :
Acetylcholinesterase (AChE) was analyzed in organotypic hippocampal slice cultures (OHSCs) during recovery from a brief period (20 min) of combined hypoxia and hypoglycemia. Simulated ischemia transiently increased AChE activity in OHSCs in a time-dependent manner reaching a 1.5 fold increase at 6 h post-ischemia. The ischemia-induced AChE increase was totally abolished by incubation with 10 microM dizocilpine (MK-801), a neuroprotective NMDA receptor blocker. |
| PubMedSearch : Saez-Valero_2003_Neurosci.Lett_348_123 |
| PubMedID: 12902034 |
Saez-Valero J, Gonzalez-Garcia C, Cena V (2003)
Acetylcholinesterase activation in organotypic rat hippocampal slice cultures deprived of oxygen and glucose
Neuroscience Letters
348 :123
Saez-Valero J, Gonzalez-Garcia C, Cena V (2003)
Neuroscience Letters
348 :123