| Title : A novel ovary-specific and ovulation-associated variant of epoxide hydrolase 2 - Shkolnik_2007_FEBS.Lett_581_4891 |
| Author(s) : Shkolnik K , Ben-Dor S , Galiani D , Hourvitz A , Dekel N |
| Ref : FEBS Letters , 581 :4891 , 2007 |
|
Abstract :
Ovulation is a complex process initiated by the surge of the pituitary luteinizing hormone (LH) that provokes the expression of specific genes. We report herein the isolation and characterization of an ovulation-associated, ovary-specific novel isoform of epoxide hydrolase 2 (Ephx2), Ephx2C. This variant is exclusively expressed in the granulosa cells of preovulatory mouse ovarian follicles. The LH-induced expression of Ephx2C is mediated by the protein kinase A and partially by the protein kinase C signaling pathways. The involvement of p38 kinase has also been demonstrated. |
| PubMedSearch : Shkolnik_2007_FEBS.Lett_581_4891 |
| PubMedID: 17900570 |
| Gene_locus related to this paper: mouse-hyes |
| Gene_locus | mouse-hyes |
Shkolnik K, Ben-Dor S, Galiani D, Hourvitz A, Dekel N (2007)
A novel ovary-specific and ovulation-associated variant of epoxide hydrolase 2
FEBS Letters
581 :4891
Shkolnik K, Ben-Dor S, Galiani D, Hourvitz A, Dekel N (2007)
FEBS Letters
581 :4891