Stein_2007_Environ.Microbiol_9_2993

Reference

Title : Whole-genome analysis of the ammonia-oxidizing bacterium, Nitrosomonas eutropha C91: implications for niche adaptation - Stein_2007_Environ.Microbiol_9_2993
Author(s) : Stein LY , Arp DJ , Berube PM , Chain PS , Hauser L , Jetten MS , Klotz MG , Larimer FW , Norton JM , Op den Camp HJ , Shin M , Wei X
Ref : Environ Microbiol , 9 :2993 , 2007
Abstract :

Analysis of the structure and inventory of the genome of Nitrosomonas eutropha C91 revealed distinctive features that may explain the adaptation of N. eutropha-like bacteria to N-saturated ecosystems. Multiple gene-shuffling events are apparent, including mobilized and replicated transposition, as well as plasmid or phage integration events into the 2.66 Mbp chromosome and two plasmids (65 and 56 kbp) of N. eutropha C91. A 117 kbp genomic island encodes multiple genes for heavy metal resistance, including clusters for copper and mercury transport, which are absent from the genomes of other ammonia-oxidizing bacteria (AOB). Whereas the sequences of the two ammonia monooxygenase and three hydroxylamine oxidoreductase gene clusters in N. eutropha C91 are highly similar to those of Nitrosomonas europaea ATCC 19718, a break of synteny in the regions flanking these clusters in each genome is evident. Nitrosomonas eutropha C91 encodes four gene clusters for distinct classes of haem-copper oxidases, two of which are not found in other aerobic AOB. This diversity of terminal oxidases may explain the adaptation of N. eutropha to environments with variable O(2) concentrations and/or high concentrations of nitrogen oxides. As with N. europaea, the N. eutropha genome lacks genes for urease metabolism, likely disadvantaging nitrosomonads in low-nitrogen or acidic ecosystems. Taken together, this analysis revealed significant genomic variation between N. eutropha C91 and other AOB, even the closely related N. europaea, and several distinctive properties of the N. eutropha genome that are supportive of niche specialization.

PubMedSearch : Stein_2007_Environ.Microbiol_9_2993
PubMedID: 17991028
Gene_locus related to this paper: nitec-metx , nitec-q0ae77 , nitec-q0ag98 , nitec-q0ahg3 , nitec-q0aix1 , nitec-q0ajy0 , nitec-q0aea2 , nitec-q0aea3

Related information

Gene_locus nitec-metx    nitec-q0ae77    nitec-q0ag98    nitec-q0ahg3    nitec-q0aix1    nitec-q0ajy0    nitec-q0aea2    nitec-q0aea3

Citations formats

Stein LY, Arp DJ, Berube PM, Chain PS, Hauser L, Jetten MS, Klotz MG, Larimer FW, Norton JM, Op den Camp HJ, Shin M, Wei X (2007)
Whole-genome analysis of the ammonia-oxidizing bacterium, Nitrosomonas eutropha C91: implications for niche adaptation
Environ Microbiol 9 :2993

Stein LY, Arp DJ, Berube PM, Chain PS, Hauser L, Jetten MS, Klotz MG, Larimer FW, Norton JM, Op den Camp HJ, Shin M, Wei X (2007)
Environ Microbiol 9 :2993