| Title : Presynaptic M1 muscarinic receptor modulates spontaneous release of acetylcholine from rat basal forebrain slices - Suzuki_1988_Neurosci.Lett_84_209 |
| Author(s) : Suzuki T , Fujimoto K , Oohata H , Kawashima K |
| Ref : Neuroscience Letters , 84 :209 , 1988 |
|
Abstract :
Spontaneous release of acetylcholine (ACh) from rat basal forebrain slices in the presence of cholinesterase inhibitor was directly determined using a specific radioimmunoassay for ACh. The release was calcium dependent. A consistent amount of ACh release was observed throughout the experiment. Atropine (10(-8) to 10(-5) M) and pirenzepine (10(-7) to 10(-5) M) enhanced spontaneous ACh release. These findings indicate the presence of an M1 muscarinic autoreceptor that modulates spontaneous release of ACh in the rat basal forebrain. |
| PubMedSearch : Suzuki_1988_Neurosci.Lett_84_209 |
| PubMedID: 3340327 |
Suzuki T, Fujimoto K, Oohata H, Kawashima K (1988)
Presynaptic M1 muscarinic receptor modulates spontaneous release of acetylcholine from rat basal forebrain slices
Neuroscience Letters
84 :209
Suzuki T, Fujimoto K, Oohata H, Kawashima K (1988)
Neuroscience Letters
84 :209