| Title : A homeobox gene essential for zebrafish notochord development - Talbot_1995_Nature_378_150 |
| Author(s) : Talbot WS , Trevarrow B , Halpern ME , Melby AE , Farr G , Postlethwait JH , Jowett T , Kimmel CB , Kimelman D |
| Ref : Nature , 378 :150 , 1995 |
|
Abstract :
The notochord is a midline mesodermal structure with an essential patterning function in all vertebrate embryos. Zebrafish floating head (flh) mutants lack a notochord, but develop with prechordal plate and other mesodermal derivatives, indicating that flh functions specifically in notochord development. We show that floating head is the zebrafish homologue of Xnot, a homeobox gene expressed in the amphibian organizer and notochord. We propose that flh regulates notochord precursor cell fate. |
| PubMedSearch : Talbot_1995_Nature_378_150 |
| PubMedID: 7477317 |
Talbot WS, Trevarrow B, Halpern ME, Melby AE, Farr G, Postlethwait JH, Jowett T, Kimmel CB, Kimelman D (1995)
A homeobox gene essential for zebrafish notochord development
Nature
378 :150
Talbot WS, Trevarrow B, Halpern ME, Melby AE, Farr G, Postlethwait JH, Jowett T, Kimmel CB, Kimelman D (1995)
Nature
378 :150