Tobin_2004_Methods.Mol.Biol_259_275

Reference

Title : G-protein-coupled receptor phosphorylation and palmitoylation - Tobin_2004_Methods.Mol.Biol_259_275
Author(s) : Tobin AB , Wheatley M
Ref : Methods Mol Biol , 259 :275 , 2004
Abstract :

It is now clear that nearly all G-protein-coupled receptors (GPCRs) are phosphorylated and palmitolyated. The process of receptor phosphorylation has been extensively studied because it offers a regulatory mechanism that is both rapid and dynamic. However, it has recently become clear that palmitoyaltion of GPCRs at C-terminal cysteine residues may also offer dynamic receptor modification. A growing number of GPCRs have been demonstrated to undergo rapid agonist-mediated changes in their palmitoylation status with functional implications to receptor signaling. This chapter aims to outline the methods we have used to investigate agonist-mediated changes in GPCR phosphorylation and palmitoylation.

PubMedSearch : Tobin_2004_Methods.Mol.Biol_259_275
PubMedID: 15250498

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Citations formats

Tobin AB, Wheatley M (2004)
G-protein-coupled receptor phosphorylation and palmitoylation
Methods Mol Biol 259 :275

Tobin AB, Wheatley M (2004)
Methods Mol Biol 259 :275