Tobin AB

General

Full name : Tobin Andrew B

First name : Andrew B

Mail : University of Glasgow, Davidson Building,G12 8QQ Glasgow - Univ of Leicester, Dept Cell Physiology & Pharmacology, Medical Sciences Building, University Rd, Leicester LE1 9HN

Zip Code :

City :

Country : United Kingdom

Email : tba@le.ac.uk

Phone :

Fax :

Website : \/\/www2.le.ac.uk\/departments\/molcellbiol\/staff\/andrew-tobin

Directory :

References (76)

Title : From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease - Brown_2021_Cell_184_5886
Author(s) : Brown AJH , Bradley SJ , Marshall FH , Brown GA , Bennett KA , Brown J , Cansfield JE , Cross DM , de Graaf C , Hudson BD , Dwomoh L , Dias JM , Errey JC , Hurrell E , Liptrot J , Mattedi G , Molloy C , Nathan PJ , Okrasa K , Osborne G , Patel JC , Pickworth M , Robertson N , Shahabi S , Bundgaard C , Phillips K , Broad LM , Goonawardena AV , Morairty SR , Browning M , Perini F , Dawson GR , Deakin JFW , Smith RT , Sexton PM , Warneck J , Vinson M , Tasker T , Tehan BG , Teobald B , Christopoulos A , Langmead CJ , Jazayeri A , Cooke RM , Rucktooa P , Congreve MS , Weir M , Tobin AB
Ref : Cell , 184 :5886 , 2021
Abstract :
PubMedSearch : Brown_2021_Cell_184_5886
PubMedID: 34822784

Title : Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs - Bradley_2020_Nat.Chem.Biol_16_240
Author(s) : Bradley SJ , Molloy C , Valuskova P , Dwomoh L , Scarpa M , Rossi M , Finlayson L , Svensson KA , Chernet E , Barth VN , Gherbi K , Sykes DA , Wilson CA , Mistry R , Sexton PM , Christopoulos A , Mogg AJ , Rosethorne EM , Sakata S , John Challiss RA , Broad LM , Tobin AB
Ref : Nat Chemical Biology , 16 :240 , 2020
Abstract :
PubMedSearch : Bradley_2020_Nat.Chem.Biol_16_240
PubMedID: 32080630

Title : M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss - Bradley_2017_J.Clin.Invest_127_487
Author(s) : Bradley SJ , Bourgognon JM , Sanger HE , Verity N , Mogg AJ , White DJ , Butcher AJ , Moreno JA , Molloy C , Macedo-Hatch T , Edwards JM , Wess J , Pawlak R , Read DJ , Sexton PM , Broad LM , Steinert JR , Mallucci GR , Christopoulos A , Felder CC , Tobin AB
Ref : J Clinical Investigation , 127 :487 , 2017
Abstract :
PubMedSearch : Bradley_2017_J.Clin.Invest_127_487
PubMedID: 27991860

Title : Identification of phosphorylation sites in the COOH-terminal tail of the mu-opioid receptor - Chen_2013_J.Neurochem_124_189
Author(s) : Chen YJ , Oldfield S , Butcher AJ , Tobin AB , Saxena K , Gurevich VV , Benovic JL , Henderson G , Kelly E
Ref : Journal of Neurochemistry , 124 :189 , 2013
Abstract :
PubMedSearch : Chen_2013_J.Neurochem_124_189
PubMedID: 23106126

Title : ERK5 Activation by Gq-Coupled Muscarinic Receptors Is Independent of Receptor Internalization and beta-Arrestin Recruitment - Sanchez-Fernandez_2013_PLoS.One_8_e84174
Author(s) : Sanchez-Fernandez G , Cabezudo S , Garcia-Hoz C , Tobin AB , Mayor F, Jr. , Ribas C
Ref : PLoS ONE , 8 :e84174 , 2013
Abstract :
PubMedSearch : Sanchez-Fernandez_2013_PLoS.One_8_e84174
PubMedID: 24358341

Title : Experimental tools for the study of protein phosphorylation in Plasmodium - Dorin-Semblat_2013_Methods.Mol.Biol_923_241
Author(s) : Dorin-Semblat D , Bottrill AR , Solyakov L , Tobin AB , Doerig C
Ref : Methods Mol Biol , 923 :241 , 2013
Abstract :
PubMedSearch : Dorin-Semblat_2013_Methods.Mol.Biol_923_241
PubMedID: 22990782

Title : The pharmacology of TUG-891, a potent and selective agonist of the free fatty acid receptor 4 (FFA4\/GPR120), demonstrates both potential opportunity and possible challenges to therapeutic agonism - Hudson_2013_Mol.Pharmacol_84_710
Author(s) : Hudson BD , Shimpukade B , Mackenzie AE , Butcher AJ , Pediani JD , Christiansen E , Heathcote H , Tobin AB , Ulven T , Milligan G
Ref : Molecular Pharmacology , 84 :710 , 2013
Abstract :
PubMedSearch : Hudson_2013_Mol.Pharmacol_84_710
PubMedID: 23979972

Title : Influence of the accessory protein SET on M3 muscarinic receptor phosphorylation and G protein coupling - Simon_2012_Mol.Pharmacol_82_17
Author(s) : Simon V , Oner SS , Cohen-Tannoudji J , Tobin AB , Lanier SM
Ref : Molecular Pharmacology , 82 :17 , 2012
Abstract :
PubMedSearch : Simon_2012_Mol.Pharmacol_82_17
PubMedID: 22466417

Title : Stimulus bias provides evidence for conformational constraints in the structure of a G protein-coupled receptor - Gregory_2012_J.Biol.Chem_287_37066
Author(s) : Gregory KJ , Sexton PM , Tobin AB , Christopoulos A
Ref : Journal of Biological Chemistry , 287 :37066 , 2012
Abstract :
PubMedSearch : Gregory_2012_J.Biol.Chem_287_37066
PubMedID: 22965232

Title : Physiological role of G-protein coupled receptor phosphorylation - Butcher_2012_Handb.Exp.Pharmacol_208_79
Author(s) : Butcher AJ , Kong KC , Prihandoko R , Tobin AB
Ref : Handbook of Experimental Pharmacology , :79 , 2012
Abstract :
PubMedSearch : Butcher_2012_Handb.Exp.Pharmacol_208_79
PubMedID: 22222696

Title : A putative homologue of CDC20\/CDH1 in the malaria parasite is essential for male gamete development - Guttery_2012_PLoS.Pathog_8_e1002554
Author(s) : Guttery DS , Ferguson DJ , Poulin B , Xu Z , Straschil U , Klop O , Solyakov L , Sandrini SM , Brady D , Nieduszynski CA , Janse CJ , Holder AA , Tobin AB , Tewari R
Ref : PLoS Pathog , 8 :e1002554 , 2012
Abstract :
PubMedSearch : Guttery_2012_PLoS.Pathog_8_e1002554
PubMedID: 22383885

Title : A unique protein phosphatase with kelch-like domains (PPKL) in Plasmodium modulates ookinete differentiation, motility and invasion - Guttery_2012_PLoS.Pathog_8_e1002948
Author(s) : Guttery DS , Poulin B , Ferguson DJ , Szoor B , Wickstead B , Carroll PL , Ramakrishnan C , Brady D , Patzewitz EM , Straschil U , Solyakov L , Green JL , Sinden RE , Tobin AB , Holder AA , Tewari R
Ref : PLoS Pathog , 8 :e1002948 , 2012
Abstract :
PubMedSearch : Guttery_2012_PLoS.Pathog_8_e1002948
PubMedID: 23028336

Title : An evolutionary perspective on the kinome of malaria parasites - Talevich_2012_Philos.Trans.R.Soc.Lond.B.Biol.Sci_367_2607
Author(s) : Talevich E , Tobin AB , Kannan N , Doerig C
Ref : Philos Trans R Soc Lond B Biol Sci , 367 :2607 , 2012
Abstract :
PubMedSearch : Talevich_2012_Philos.Trans.R.Soc.Lond.B.Biol.Sci_367_2607
PubMedID: 22889911

Title : Spatiotemporal and functional characterisation of the Plasmodium falciparum cGMP-dependent protein kinase - Hopp_2012_PLoS.One_7_e48206
Author(s) : Hopp CS , Flueck C , Solyakov L , Tobin AB , Baker DA
Ref : PLoS ONE , 7 :e48206 , 2012
Abstract :
PubMedSearch : Hopp_2012_PLoS.One_7_e48206
PubMedID: 23139764

Title : Insights into the Plasmodium falciparum schizont phospho-proteome - Lasonder_2012_Microbes.Infect_14_811
Author(s) : Lasonder E , Treeck M , Alam M , Tobin AB
Ref : Microbes Infect , 14 :811 , 2012
Abstract :
PubMedSearch : Lasonder_2012_Microbes.Infect_14_811
PubMedID: 22569589

Title : Plasmodium kinases as targets for new-generation antimalarials - Lucet_2012_Future.Med.Chem_4_2295
Author(s) : Lucet IS , Tobin AB , Drewry D , Wilks AF , Doerig C
Ref : Future Med Chem , 4 :2295 , 2012
Abstract :
PubMedSearch : Lucet_2012_Future.Med.Chem_4_2295
PubMedID: 23234552

Title : Differential G-protein-coupled receptor phosphorylation provides evidence for a signaling bar code - Butcher_2011_J.Biol.Chem_286_11506
Author(s) : Butcher AJ , Prihandoko R , Kong KC , McWilliams P , Edwards JM , Bottrill A , Mistry S , Tobin AB
Ref : Journal of Biological Chemistry , 286 :11506 , 2011
Abstract :
PubMedSearch : Butcher_2011_J.Biol.Chem_286_11506
PubMedID: 21177246

Title : Examining site-specific GPCR phosphorylation - Butcher_2011_Methods.Mol.Biol_746_237
Author(s) : Butcher AJ , Tobin AB , Kong KC
Ref : Methods Mol Biol , 746 :237 , 2011
Abstract :
PubMedSearch : Butcher_2011_Methods.Mol.Biol_746_237
PubMedID: 21607860

Title : Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum - Solyakov_2011_Nat.Commun_2_565
Author(s) : Solyakov L , Halbert J , Alam MM , Semblat JP , Dorin-Semblat D , Reininger L , Bottrill AR , Mistry S , Abdi A , Fennell C , Holland Z , Demarta C , Bouza Y , Sicard A , Nivez MP , Eschenlauer S , Lama T , Thomas DC , Sharma P , Agarwal S , Kern S , Pradel G , Graciotti M , Tobin AB , Doerig C
Ref : Nat Commun , 2 :565 , 2011
Abstract :
PubMedSearch : Solyakov_2011_Nat.Commun_2_565
PubMedID: 22127061

Title : The role of M(3)-muscarinic receptor signaling in insulin secretion - Kong_2011_Commun.Integr.Biol_4_489
Author(s) : Kong KC , Tobin AB
Ref : Commun Integr Biol , 4 :489 , 2011
Abstract :
PubMedSearch : Kong_2011_Commun.Integr.Biol_4_489
PubMedID: 21966580

Title : Developing chemical genetic approaches to explore G protein-coupled receptor function: validation of the use of a receptor activated solely by synthetic ligand (RASSL) - Alvarez-Curto_2011_Mol.Pharmacol_80_1033
Author(s) : Alvarez-Curto E , Prihandoko R , Tautermann CS , Zwier JM , Pediani JD , Lohse MJ , Hoffmann C , Tobin AB , Milligan G
Ref : Molecular Pharmacology , 80 :1033 , 2011
Abstract :
PubMedSearch : Alvarez-Curto_2011_Mol.Pharmacol_80_1033
PubMedID: 21880827

Title : The M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation\/arrestin-dependent manner - Poulin_2010_Proc.Natl.Acad.Sci.U.S.A_107_9440
Author(s) : Poulin B , Butcher A , McWilliams P , Bourgognon JM , Pawlak R , Kong KC , Bottrill A , Mistry S , Wess J , Rosethorne EM , Charlton SJ , Tobin AB
Ref : Proc Natl Acad Sci U S A , 107 :9440 , 2010
Abstract :
PubMedSearch : Poulin_2010_Proc.Natl.Acad.Sci.U.S.A_107_9440
PubMedID: 20439723

Title : Parasite protein kinases: at home and abroad - Doerig_2010_Cell.Host.Microbe_8_305
Author(s) : Doerig C , Tobin AB
Ref : Cell Host Microbe , 8 :305 , 2010
Abstract :
PubMedSearch : Doerig_2010_Cell.Host.Microbe_8_305
PubMedID: 20951964

Title : Identification of orthosteric and allosteric site mutations in M2 muscarinic acetylcholine receptors that contribute to ligand-selective signaling bias - Gregory_2010_J.Biol.Chem_285_7459
Author(s) : Gregory KJ , Hall NE , Tobin AB , Sexton PM , Christopoulos A
Ref : Journal of Biological Chemistry , 285 :7459 , 2010
Abstract :
PubMedSearch : Gregory_2010_J.Biol.Chem_285_7459
PubMedID: 20051519

Title : M3-muscarinic receptor promotes insulin release via receptor phosphorylation\/arrestin-dependent activation of protein kinase D1 - Kong_2010_Proc.Natl.Acad.Sci.U.S.A_107_21181
Author(s) : Kong KC , Butcher AJ , McWilliams P , Jones D , Wess J , Hamdan FF , Werry T , Rosethorne EM , Charlton SJ , Munson SE , Cragg HA , Smart AD , Tobin AB
Ref : Proc Natl Acad Sci U S A , 107 :21181 , 2010
Abstract :
PubMedSearch : Kong_2010_Proc.Natl.Acad.Sci.U.S.A_107_21181
PubMedID: 21078968

Title : N-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neurons - Butcher_2009_J.Biol.Chem_284_17147
Author(s) : Butcher AJ , Torrecilla I , Young KW , Kong KC , Mistry SC , Bottrill AR , Tobin AB
Ref : Journal of Biological Chemistry , 284 :17147 , 2009
Abstract :
PubMedSearch : Butcher_2009_J.Biol.Chem_284_17147
PubMedID: 19332541

Title : Regulation of p53 expression, phosphorylation and subcellular localization by a G-protein-coupled receptor - Solyakov_2009_Oncogene_28_3619
Author(s) : Solyakov L , Sayan E , Riley J , Pointon A , Tobin AB
Ref : Oncogene , 28 :3619 , 2009
Abstract :
PubMedSearch : Solyakov_2009_Oncogene_28_3619
PubMedID: 19648965

Title : G-protein-coupled receptor structure: what can we learn? - Tobin_2009_F1000.Biol.Rep_1_11
Author(s) : Tobin AB
Ref : F1000 Biol Rep , 1 :11 , 2009
Abstract :
PubMedSearch : Tobin_2009_F1000.Biol.Rep_1_11
PubMedID: 20948675

Title : Full and partial agonists of muscarinic M3 receptors reveal single and oscillatory Ca2+ responses by beta 2-adrenoceptors - Kurian_2009_J.Pharmacol.Exp.Ther_330_502
Author(s) : Kurian N , Hall CJ , Wilkinson GF , Sullivan M , Tobin AB , Willars GB
Ref : Journal of Pharmacology & Experimental Therapeutics , 330 :502 , 2009
Abstract :
PubMedSearch : Kurian_2009_J.Pharmacol.Exp.Ther_330_502
PubMedID: 19420300

Title : Protein kinases of malaria parasites: an update - Doerig_2008_Trends.Parasitol_24_570
Author(s) : Doerig C , Billker O , Haystead T , Sharma P , Tobin AB , Waters NC
Ref : Trends Parasitol , 24 :570 , 2008
Abstract :
PubMedSearch : Doerig_2008_Trends.Parasitol_24_570
PubMedID: 18845480

Title : G-protein-coupled receptor phosphorylation: where, when and by whom - Tobin_2008_Br.J.Pharmacol_153 Suppl 1_S167
Author(s) : Tobin AB
Ref : British Journal of Pharmacology , 153 Suppl 1 :S167 , 2008
Abstract :
PubMedSearch : Tobin_2008_Br.J.Pharmacol_153 Suppl 1_S167
PubMedID: 18193069

Title : Location, location, location...site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling - Tobin_2008_Trends.Pharmacol.Sci_29_413
Author(s) : Tobin AB , Butcher AJ , Kong KC
Ref : Trends in Pharmacological Sciences , 29 :413 , 2008
Abstract :
PubMedSearch : Tobin_2008_Trends.Pharmacol.Sci_29_413
PubMedID: 18606460

Title : Modulation of hERG potassium currents in HEK-293 cells by protein kinase C. Evidence for direct phosphorylation of pore forming subunits - Cockerill_2007_J.Physiol_581_479
Author(s) : Cockerill SL , Tobin AB , Torrecilla I , Willars GB , Standen NB , Mitcheson JS
Ref : Journal of Physiology , 581 :479 , 2007
Abstract :
PubMedSearch : Cockerill_2007_J.Physiol_581_479
PubMedID: 17363390

Title : Phosphorylation and regulation of a G protein-coupled receptor by protein kinase CK2 - Torrecilla_2007_J.Cell.Biol_177_127
Author(s) : Torrecilla I , Spragg EJ , Poulin B , McWilliams PJ , Mistry SC , Blaukat A , Tobin AB
Ref : Journal of Cell Biology , 177 :127 , 2007
Abstract :
PubMedSearch : Torrecilla_2007_J.Cell.Biol_177_127
PubMedID: 17403928

Title : Transient hypoxia induces sequestration of M1 and M2 muscarinic acetylcholine receptors - Mou_2006_J.Neurochem_96_510
Author(s) : Mou L , Gates A , Mosser VA , Tobin AB , Jackson DA
Ref : Journal of Neurochemistry , 96 :510 , 2006
Abstract :
PubMedSearch : Mou_2006_J.Neurochem_96_510
PubMedID: 16336219

Title : The proto-oncogene SET interacts with muscarinic receptors and attenuates receptor signaling - Simon_2006_J.Biol.Chem_281_40310
Author(s) : Simon V , Guidry J , Gettys TW , Tobin AB , Lanier SM
Ref : Journal of Biological Chemistry , 281 :40310 , 2006
Abstract :
PubMedSearch : Simon_2006_J.Biol.Chem_281_40310
PubMedID: 17065150

Title : Co-ordinated covalent modification of G-protein coupled receptors - Torrecilla_2006_Curr.Pharm.Des_12_1797
Author(s) : Torrecilla I , Tobin AB
Ref : Curr Pharm Des , 12 :1797 , 2006
Abstract :
PubMedSearch : Torrecilla_2006_Curr.Pharm.Des_12_1797
PubMedID: 16712489

Title : Antimuscarinic antibodies in Sjogren's syndrome: where are we, and where are we going? -
Author(s) : Dawson L , Tobin AB , Smith P , Gordon T
Ref : Arthritis Rheum , 52 :2984 , 2005
PubMedID: 16200578

Title : Signalling of the M3-muscarinic receptor to the anti-apoptotic pathway - Budd_2004_Biochem.J_381_43
Author(s) : Budd DC , Spragg EJ , Ridd K , Tobin AB
Ref : Biochemical Journal , 381 :43 , 2004
Abstract :
PubMedSearch : Budd_2004_Biochem.J_381_43
PubMedID: 15068397

Title : Regulation of casein kinase-2 (CK2) activity by inositol phosphates - Solyakov_2004_J.Biol.Chem_279_43403
Author(s) : Solyakov L , Cain K , Tracey BM , Jukes R , Riley AM , Potter BV , Tobin AB
Ref : Journal of Biological Chemistry , 279 :43403 , 2004
Abstract :
PubMedSearch : Solyakov_2004_J.Biol.Chem_279_43403
PubMedID: 15297462

Title : G-protein-coupled receptor phosphorylation and palmitoylation - Tobin_2004_Methods.Mol.Biol_259_275
Author(s) : Tobin AB , Wheatley M
Ref : Methods Mol Biol , 259 :275 , 2004
Abstract :
PubMedSearch : Tobin_2004_Methods.Mol.Biol_259_275
PubMedID: 15250498

Title : G-protein-coupled receptor regulation of P2X1 receptors does not involve direct channel phosphorylation - Vial_2004_Biochem.J_382_101
Author(s) : Vial C , Tobin AB , Evans RJ
Ref : Biochemical Journal , 382 :101 , 2004
Abstract :
PubMedSearch : Vial_2004_Biochem.J_382_101
PubMedID: 15144237

Title : The C-terminal tail of the M3-muscarinic receptor possesses anti-apoptotic properties - Budd_2003_J.Biol.Chem_278_19565
Author(s) : Budd DC , McDonald J , Emsley N , Cain K , Tobin AB
Ref : Journal of Biological Chemistry , 278 :19565 , 2003
Abstract :
PubMedSearch : Budd_2003_J.Biol.Chem_278_19565
PubMedID: 12649280

Title : The anti-apoptotic response of the Gq\/11-coupled muscarinic receptor family - Tobin_2003_Biochem.Soc.Trans_31_1182
Author(s) : Tobin AB , Budd DC
Ref : Biochemical Society Transactions , 31 :1182 , 2003
Abstract :
PubMedSearch : Tobin_2003_Biochem.Soc.Trans_31_1182
PubMedID: 14641022

Title : Are we beta-ARKing up the wrong tree? Casein kinase 1 alpha provides an additional pathway for GPCR phosphorylation - Tobin_2002_Trends.Pharmacol.Sci_23_337
Author(s) : Tobin AB
Ref : Trends in Pharmacological Sciences , 23 :337 , 2002
Abstract :
PubMedSearch : Tobin_2002_Trends.Pharmacol.Sci_23_337
PubMedID: 12119155

Title : Phosphorylation of the Gq\/11-coupled m3-muscarinic receptor is involved in receptor activation of the ERK-1\/2 mitogen-activated protein kinase pathway - Budd_2001_J.Biol.Chem_276_4581
Author(s) : Budd DC , Willars GB , McDonald JE , Tobin AB
Ref : Journal of Biological Chemistry , 276 :4581 , 2001
Abstract :
PubMedSearch : Budd_2001_J.Biol.Chem_276_4581
PubMedID: 11083874

Title : Palmitoylation of the vasopressin V1a receptor reveals different conformational requirements for signaling, agonist-induced receptor phosphorylation, and sequestration - Hawtin_2001_J.Biol.Chem_276_38139
Author(s) : Hawtin SR , Tobin AB , Patel S , Wheatley M
Ref : Journal of Biological Chemistry , 276 :38139 , 2001
Abstract :
PubMedSearch : Hawtin_2001_J.Biol.Chem_276_38139
PubMedID: 11466323

Title : Phosphorylation of a synaptic vesicle-associated protein by an inositol hexakisphosphate-regulated protein kinase - Hilton_2001_J.Biol.Chem_276_16341
Author(s) : Hilton JM , Plomann M , Ritter B , Modregger J , Freeman HN , Falck JR , Krishna UM , Tobin AB
Ref : Journal of Biological Chemistry , 276 :16341 , 2001
Abstract :
PubMedSearch : Hilton_2001_J.Biol.Chem_276_16341
PubMedID: 11278843

Title : Phosphorylation and regulation of a Gq\/11-coupled receptor by casein kinase 1alpha - Budd_2000_J.Biol.Chem_275_19667
Author(s) : Budd DC , McDonald JE , Tobin AB
Ref : Journal of Biological Chemistry , 275 :19667 , 2000
Abstract :
PubMedSearch : Budd_2000_J.Biol.Chem_275_19667
PubMedID: 10777483

Title : Cross talk between m3-muscarinic and beta(2)-adrenergic receptors at the level of receptor phosphorylation and desensitization - Budd_1999_Mol.Pharmacol_56_813
Author(s) : Budd DC , Challiss RA , Young KW , Tobin AB
Ref : Molecular Pharmacology , 56 :813 , 1999
Abstract :
PubMedSearch : Budd_1999_Mol.Pharmacol_56_813
PubMedID: 10496966

Title : Activation of the mitogen-activated protein kinase pathway by a Gq\/11-coupled muscarinic receptor is independent of receptor internalization - Budd_1999_J.Biol.Chem_274_12355
Author(s) : Budd DC , Rae A , Tobin AB
Ref : Journal of Biological Chemistry , 274 :12355 , 1999
Abstract :
PubMedSearch : Budd_1999_J.Biol.Chem_274_12355
PubMedID: 10212206

Title : Differential regulation of muscarinic M1 and M3 receptors by a putative phosphorylation domain - Shockley_1999_Eur.J.Pharmacol_377_137
Author(s) : Shockley MS , Tolbert LM , Tobin AB , Nahorski SR , Sadee W , Lameh J
Ref : European Journal of Pharmacology , 377 :137 , 1999
Abstract :
PubMedSearch : Shockley_1999_Eur.J.Pharmacol_377_137
PubMedID: 10448936

Title : Agonist-induced desensitization and phosphorylation of m1-muscarinic receptors - Waugh_1999_Biochem.J_338 ( Pt 1)_175
Author(s) : Waugh MG , Challiss RA , Berstein G , Nahorski SR , Tobin AB
Ref : Biochemical Journal , 338 ( Pt 1) :175 , 1999
Abstract :
PubMedSearch : Waugh_1999_Biochem.J_338 ( Pt 1)_175
PubMedID: 9931314

Title : Receptor-mediated endocytosis of albumin by kidney proximal tubule cells is regulated by phosphatidylinositide 3-kinase - Brunskill_1998_J.Clin.Invest_101_2140
Author(s) : Brunskill NJ , Stuart J , Tobin AB , Walls J , Nahorski SR
Ref : J Clinical Investigation , 101 :2140 , 1998
Abstract :
PubMedSearch : Brunskill_1998_J.Clin.Invest_101_2140
PubMedID: 9593770

Title : Muscarinic M3 receptor coupling and regulation - Nahorski_1997_Life.Sci_60(13-14)_1039
Author(s) : Nahorski SR , Tobin AB , Willars GB
Ref : Life Sciences , 60 :1039 , 1997
Abstract :
PubMedSearch : Nahorski_1997_Life.Sci_60(13-14)_1039
PubMedID: 9121345

Title : Phosphorylation of phospholipase C-coupled receptors - Tobin_1997_Pharmacol.Ther_75_135
Author(s) : Tobin AB
Ref : Pharmacol Ther , 75 :135 , 1997
Abstract :
PubMedSearch : Tobin_1997_Pharmacol.Ther_75_135
PubMedID: 9428002

Title : Protocols employed in the investigation of G protein-coupled receptor phosphorylation -
Author(s) : Tobin AB
Ref : Methods Mol Biol , 83 :227 , 1997
PubMedID: 9210149

Title : Poster: Characterisation of the muscarinic receptor kinase MRK -
Author(s) : Tobin AB , Nahorski SR
Ref : Life Sciences , 60 :1186 , 1997
PubMedID:

Title : Stimulus-dependent phosphorylation of G-protein-coupled receptors by casein kinase 1alpha - Tobin_1997_J.Biol.Chem_272_20844
Author(s) : Tobin AB , Totty NF , Sterlin AE , Nahorski SR
Ref : Journal of Biological Chemistry , 272 :20844 , 1997
Abstract :
PubMedSearch : Tobin_1997_J.Biol.Chem_272_20844
PubMedID: 9252410

Title : Identification of a novel receptor kinase that phosphorylates a phospholipase C-linked muscarinic receptor - Tobin_1996_J.Biol.Chem_271_3907
Author(s) : Tobin AB , Keys B , Nahorski SR
Ref : Journal of Biological Chemistry , 271 :3907 , 1996
Abstract :
PubMedSearch : Tobin_1996_J.Biol.Chem_271_3907
PubMedID: 8632012

Title : Poster: Agonist induced phosphorylation of M1 muscarinic receptors -
Author(s) : Waugh MG , Nahorski SR , Tobin AB
Ref : Life Sciences , 56(11-12) :1026 , 1995
PubMedID:

Title : Differential coupling of m1, m2 and m3 muscarinic receptor subtypes to inositol 1,4,5-trisphosphate and adenosine 3',5'-cyclic monophosphate accumulation in Chinese hamster ovary cells - Burford_1995_J.Pharmacol.Exp.Ther_274_134
Author(s) : Burford NT , Tobin AB , Nahorski SR
Ref : Journal of Pharmacology & Experimental Therapeutics , 274 :134 , 1995
Abstract :
PubMedSearch : Burford_1995_J.Pharmacol.Exp.Ther_274_134
PubMedID: 7616390

Title : Poster: Isolation of two novel g-protein-linked receptor kinases, MRK-1 and MRK-2 that phosphorylate the m3-muscarinic receptor -
Author(s) : Tobin AB , Nahorski SR
Ref : Life Sciences , 56(11-12) :1029 , 1995
PubMedID:

Title : Relationship between agonist binding, phosphorylation and immunoprecipitation of the m3-muscarinic receptor, and second messenger responses - Tobin_1995_Br.J.Pharmacol_116_1723
Author(s) : Tobin AB , Willars GB , Burford NT , Nahorski SR
Ref : British Journal of Pharmacology , 116 :1723 , 1995
Abstract :
PubMedSearch : Tobin_1995_Br.J.Pharmacol_116_1723
PubMedID: 8528551

Title : Coupling of muscarinic m1, m2 and m3 acetylcholine receptors, expressed in Chinese hamster ovary cells, to pertussis toxin-sensitive\/insensitive guanine nucleotide-binding proteins - Burford_1995_Eur.J.Pharmacol_289_343
Author(s) : Burford NT , Tobin AB , Nahorski SR
Ref : European Journal of Pharmacology , 289 :343 , 1995
Abstract :
PubMedSearch : Burford_1995_Eur.J.Pharmacol_289_343
PubMedID: 7621908

Title : Muscarinic receptor-mediated inositol 1,4,5-trisphosphate formation in SH-SY5Y neuroblastoma cells is regulated acutely by cytosolic Ca2+ and by rapid desensitization - Wojcikiewicz_1994_J.Neurochem_63_177
Author(s) : Wojcikiewicz RJ , Tobin AB , Nahorski SR
Ref : Journal of Neurochemistry , 63 :177 , 1994
Abstract :
PubMedSearch : Wojcikiewicz_1994_J.Neurochem_63_177
PubMedID: 8207426

Title : Poster: m3-muscarinic receptor specific antisera for use in studies of muscarinic receptor desensitisation -
Author(s) : Tobin AB , Nahorski SR
Ref : Life Sciences , 52(5-6) :585 , 1993
PubMedID:

Title : Rapid agonist-mediated phosphorylation of m3-muscarinic receptors revealed by immunoprecipitation - Tobin_1993_J.Biol.Chem_268_9817
Author(s) : Tobin AB , Nahorski SR
Ref : Journal of Biological Chemistry , 268 :9817 , 1993
Abstract :
PubMedSearch : Tobin_1993_J.Biol.Chem_268_9817
PubMedID: 8486662

Title : Phosphorylation of a phosphoinositidase C-linked muscarinic receptor by a novel kinase distinct from beta-adrenergic receptor kinase - Tobin_1993_FEBS.Lett_335_353
Author(s) : Tobin AB , Keys B , Nahorski SR
Ref : FEBS Letters , 335 :353 , 1993
Abstract :
PubMedSearch : Tobin_1993_FEBS.Lett_335_353
PubMedID: 8262183

Title : Desensitization of cell signalling mediated by phosphoinositidase C - Wojcikiewicz_1993_Trends.Pharmacol.Sci_14_279
Author(s) : Wojcikiewicz RJ , Tobin AB , Nahorski SR
Ref : Trends in Pharmacological Sciences , 14 :279 , 1993
Abstract :
PubMedSearch : Wojcikiewicz_1993_Trends.Pharmacol.Sci_14_279
PubMedID: 8212322

Title : Rapid desensitization of muscarinic m3 receptor-stimulated polyphosphoinositide responses - Tobin_1992_Mol.Pharmacol_42_1042
Author(s) : Tobin AB , Lambert DG , Nahorski SR
Ref : Molecular Pharmacology , 42 :1042 , 1992
Abstract :
PubMedSearch : Tobin_1992_Mol.Pharmacol_42_1042
PubMedID: 1480131

Title : Evidence for the presence of serotonin receptors negatively coupled to adenylate cyclase in the rabbit iris-ciliary body - Tobin_1989_J.Neurochem_53_686
Author(s) : Tobin AB , Osborne NN
Ref : Journal of Neurochemistry , 53 :686 , 1989
Abstract :
PubMedSearch : Tobin_1989_J.Neurochem_53_686
PubMedID: 2547897

Title : Role of inositol trisphosphate as a second messenger in signal transduction processes: an essay - Osborne_1988_Neurochem.Res_13_177
Author(s) : Osborne NN , Tobin AB , Ghazi H
Ref : Neurochem Res , 13 :177 , 1988
Abstract :
PubMedSearch : Osborne_1988_Neurochem.Res_13_177
PubMedID: 2838762

Title : Evidence for the presence of cholinergic muscarinic receptors negatively linked to adenylate cyclase in the iris-ciliary body - Tobin_1988_Neurochem.Int_13_517
Author(s) : Tobin AB , Osborne NN
Ref : Neurochem Int , 13 :517 , 1988
Abstract :
PubMedSearch : Tobin_1988_Neurochem.Int_13_517
PubMedID: 20501312

Title : Evidence for the presence of serotonergic nerves and receptors in the iris-ciliary body complex of the rabbit - Tobin_1988_J.Neurosci_8_3713
Author(s) : Tobin AB , Unger W , Osborne NN
Ref : Journal of Neuroscience , 8 :3713 , 1988
Abstract :
PubMedSearch : Tobin_1988_J.Neurosci_8_3713
PubMedID: 3193177

Title : Serotonin-accumulating cells in the iris-ciliary body and cornea of various species - Osborne_1987_Exp.Eye.Res_44_731
Author(s) : Osborne NN , Tobin AB
Ref : Experimental Eye Research , 44 :731 , 1987
Abstract :
PubMedSearch : Osborne_1987_Exp.Eye.Res_44_731
PubMedID: 3653269