| Title : Positive effects of allosteric modulators on the binding properties and the function of muscarinic acetylcholine receptors - Tucek_1998_J.Physiol.Paris_92_241 |
| Author(s) : Tucek S , Jakubik J , Dolezal V , El-Fakahany EE |
| Ref : Journal de Physiologie (Paris) , 92 :241 , 1998 |
|
Abstract :
Data are reviewed indicating that allosteric modulators can enhance the affinities of muscarinic receptors for their antagonists and agonists, that the enhancement of the affinity for agonists is relevant functionally, and that the allosterically induced conformational change also affects the interaction between the receptors and the G proteins. |
| PubMedSearch : Tucek_1998_J.Physiol.Paris_92_241 |
| PubMedID: 9789816 |
Tucek S, Jakubik J, Dolezal V, El-Fakahany EE (1998)
Positive effects of allosteric modulators on the binding properties and the function of muscarinic acetylcholine receptors
Journal de Physiologie (Paris)
92 :241
Tucek S, Jakubik J, Dolezal V, El-Fakahany EE (1998)
Journal de Physiologie (Paris)
92 :241