El-Fakahany EE

General

Full name : El-Fakahany Esam E

First name : Esam E

Mail : Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, Minnesota

Zip Code :

City :

Country : USA

Email : elfak001@umn.edu

Phone :

Fax :

Website : \/\/www.pharmacy.umn.edu\/bio\/cop-experts\/esam-el-fakahany

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Comment

References (77)

Title : Lipid-Based Diets Improve Muscarinic Neurotransmission in the Hippocampus of Transgenic APPswe\/PS1dE9 Mice - Janickova_2015_Curr.Alzheimer.Res_12_923
Author(s) : Janickova H , Rudajev V , Dolejsi E , Koivisto H , Jakubik J , Tanila H , El-Fakahany EE , Dolezal V
Ref : Curr Alzheimer Res , 12 :923 , 2015
Abstract :
PubMedSearch : Janickova_2015_Curr.Alzheimer.Res_12_923
PubMedID: 26502816

Title : Classical and atypical agonists activate M1 muscarinic acetylcholine receptors through common mechanisms - Randakova_2015_Pharmacol.Res_97_27
Author(s) : Randakova A , Dolejsi E , Rudajev V , Zimcik P , Dolezal V , El-Fakahany EE , Jakubik J
Ref : Pharmacol Res , 97 :27 , 2015
Abstract :
PubMedSearch : Randakova_2015_Pharmacol.Res_97_27
PubMedID: 25882246

Title : Outline of therapeutic interventions with muscarinic receptor-mediated transmission - Jakubik_2014_Physiol.Res_63 Suppl 1_S177
Author(s) : Jakubik J , Santruckova E , Randakova A , Janickova H , Zimcik P , Rudajev V , Michal P , El-Fakahany EE , Dolezal V
Ref : Physiol Res , 63 Suppl 1 :S177 , 2014
Abstract :
PubMedSearch : Jakubik_2014_Physiol.Res_63 Suppl 1_S177
PubMedID: 24564657

Title : Uncoupling of M1 muscarinic receptor\/G-protein interaction by amyloid beta(1-42) - Janickova_2013_Neuropharmacol_67_272
Author(s) : Janickova H , Rudajev V , Zimcik P , Jakubik J , Tanila H , El-Fakahany EE , Dolezal V
Ref : Neuropharmacology , 67 :272 , 2013
Abstract :
PubMedSearch : Janickova_2013_Neuropharmacol_67_272
PubMedID: 23206502

Title : Subtype differences in pre-coupling of muscarinic acetylcholine receptors - Jakubik_2011_PLoS.One_6_e27732
Author(s) : Jakubik J , Janickova H , Randakova A , El-Fakahany EE , Dolezal V
Ref : PLoS ONE , 6 :e27732 , 2011
Abstract :
PubMedSearch : Jakubik_2011_PLoS.One_6_e27732
PubMedID: 22110745

Title : Pharmacological evaluation of the long-term effects of xanomeline on the M(1) muscarinic acetylcholine receptor - Grant_2010_PLoS.One_5_e15722
Author(s) : Grant MK , Noetzel MJ , De Lorme KC , Jakubik J , Dolezal V , El-Fakahany EE
Ref : PLoS ONE , 5 :e15722 , 2010
Abstract :
PubMedSearch : Grant_2010_PLoS.One_5_e15722
PubMedID: 21203415

Title : Divergence of allosteric effects of rapacuronium on binding and function of muscarinic receptors - Jakubik_2009_BMC.Pharmacol_9_15
Author(s) : Jakubik J , Randakova A , El-Fakahany EE , Dolezal V
Ref : BMC Pharmacol , 9 :15 , 2009
Abstract :
PubMedSearch : Jakubik_2009_BMC.Pharmacol_9_15
PubMedID: 20038295

Title : Wash-resistantly bound xanomeline inhibits acetylcholine release by persistent activation of presynaptic M(2) and M(4) muscarinic receptors in rat brain - Machova_2007_J.Pharmacol.Exp.Ther_322_316
Author(s) : Machova E , Jakubik J , El-Fakahany EE , Dolezal V
Ref : Journal of Pharmacology & Experimental Therapeutics , 322 :316 , 2007
Abstract :
PubMedSearch : Machova_2007_J.Pharmacol.Exp.Ther_322_316
PubMedID: 17446301

Title : Differences in kinetics of xanomeline binding and selectivity of activation of G proteins at M(1) and M(2) muscarinic acetylcholine receptors - Jakubik_2006_Mol.Pharmacol_70_656
Author(s) : Jakubik J , El-Fakahany EE , Dolezal V
Ref : Molecular Pharmacology , 70 :656 , 2006
Abstract :
PubMedSearch : Jakubik_2006_Mol.Pharmacol_70_656
PubMedID: 16675658

Title : Allosteric modulation by persistent binding of xanomeline of the interaction of competitive ligands with the M1 muscarinic acetylcholine receptor - Jakubik_2002_J.Pharmacol.Exp.Ther_301_1033
Author(s) : Jakubik J , Tucek S , El-Fakahany EE
Ref : Journal of Pharmacology & Experimental Therapeutics , 301 :1033 , 2002
Abstract :
PubMedSearch : Jakubik_2002_J.Pharmacol.Exp.Ther_301_1033
PubMedID: 12023535

Title : Synthesis and pharmacological evaluation of dimeric muscarinic acetylcholine receptor agonists - Christopoulos_2001_J.Pharmacol.Exp.Ther_298_1260
Author(s) : Christopoulos A , Grant MK , Ayoubzadeh N , Kim ON , Sauerberg P , Jeppesen L , El-Fakahany EE
Ref : Journal of Pharmacology & Experimental Therapeutics , 298 :1260 , 2001
Abstract :
PubMedSearch : Christopoulos_2001_J.Pharmacol.Exp.Ther_298_1260
PubMedID: 11504829

Title : Further evidence for the heterogeneity of functional muscarinic receptors in guinea pig gallbladder - Akici_2000_Eur.J.Pharmacol_388_115
Author(s) : Akici A , Karaalp A , Iskender E , Christopoulos A , El-Fakahany EE , Oktay S
Ref : European Journal of Pharmacology , 388 :115 , 2000
Abstract :
PubMedSearch : Akici_2000_Eur.J.Pharmacol_388_115
PubMedID: 10657554

Title : Evidence for a tandem two-site model of ligand binding to muscarinic acetylcholine receptors - Jakubik_2000_J.Biol.Chem_275_18836
Author(s) : Jakubik J , El-Fakahany EE , Tucek S
Ref : Journal of Biological Chemistry , 275 :18836 , 2000
Abstract :
PubMedSearch : Jakubik_2000_J.Biol.Chem_275_18836
PubMedID: 10749854

Title : Transducer abstraction: a novel approach to the detection of partial agonist efficacy in radioligand binding studies - Christopoulos_2000_J.Pharmacol.Toxicol.Methods_43_55
Author(s) : Christopoulos A , Grant MK , El-Fakahany EE
Ref : Journal of Pharmacological & Toxicological Methodsods , 43 :55 , 2000
Abstract :
PubMedSearch : Christopoulos_2000_J.Pharmacol.Toxicol.Methods_43_55
PubMedID: 11091130

Title : Characterization of the subtype selectivity of the allosteric modulator heptane-1,7-bis-(dimethyl-3'-phthalimidopropyl) ammonium bromide (C7\/3-phth) at cloned muscarinic acetylcholine receptors - Christopoulos_1999_Biochem.Pharmacol_57_171
Author(s) : Christopoulos A , Sorman JL , Mitchelson F , El-Fakahany EE
Ref : Biochemical Pharmacology , 57 :171 , 1999
Abstract :
PubMedSearch : Christopoulos_1999_Biochem.Pharmacol_57_171
PubMedID: 9890565

Title : Poster: Investigating the mechanisms of upregulation of neuronal nitric oxide synthase (nNOS) by the muscarinic M1 receptor -
Author(s) : Cuadra AE , El-Fakahany EE
Ref : Life Sciences , 64 :573 , 1999
PubMedID:

Title : Poster: Pharmacological determination of the interaction of xanomeline with M1 muscarinic acetylcholine receptors -
Author(s) : Parsons AM , Christopoulos A , El-Fakahany EE
Ref : Life Sciences , 64 :578 , 1999
PubMedID:

Title : Poster: A novel and simple approach to detecting partial agonist efficacy in radioligand binding experiments -
Author(s) : Christopoulos A , Grant MK , El-Fakahany EE
Ref : Life Sciences , 64 :568 , 1999
PubMedID:

Title : Poster: M2 and M4 muscarinic receptor subtypes couple to activation of endothelial nitric oxide synthase -
Author(s) : Waid DK , El-Fakahany EE
Ref : Life Sciences , 64 :573 , 1999
PubMedID:

Title : Poster: Characterization of the subtype selectivity of the allosteric modulator, C7\/3-phth, at cloned muscarinic acetylcholine receptors -
Author(s) : El-Fakahany EE , Christopoulos A , Sorman JL , Mitchelson F
Ref : Life Sciences , 64 :561 , 1999
PubMedID:

Title : Poster: Distinct muscarinic receptor subbtypes linked to different sources of calcium in guinea-pig gallbladder -
Author(s) : Oktay S , Akici A , Karaalp A , El-Fakahany EE
Ref : Life Sciences , 64 :580 , 1999
PubMedID:

Title : Regulation of acetylcholine binding by ATP at the muscarinic M(1) receptor in intact CHO cells - Grant_1999_Brain.Res_839_94
Author(s) : Grant MK , Christopoulos A , El-Fakahany EE
Ref : Brain Research , 839 :94 , 1999
Abstract :
PubMedSearch : Grant_1999_Brain.Res_839_94
PubMedID: 10482803

Title : Poster: Investigation of the multiple agonist affinity states at the M1 muscarinic acetylcholine receptor in intact and broken cell binding experiments -
Author(s) : Grant MK , Christopoulos A , Sorman JL , El-Fakahany EE
Ref : Life Sciences , 64 :567 , 1999
PubMedID:

Title : Pharmacological analysis of the novel mode of interaction between xanomeline and the M1 muscarinic acetylcholine receptor - Christopoulos_1999_J.Pharmacol.Exp.Ther_289_1220
Author(s) : Christopoulos A , Parsons AM , El-Fakahany EE
Ref : Journal of Pharmacology & Experimental Therapeutics , 289 :1220 , 1999
Abstract :
PubMedSearch : Christopoulos_1999_J.Pharmacol.Exp.Ther_289_1220
PubMedID: 10336509

Title : The assessment of antagonist potency under conditions of transient response kinetics - Christopoulos_1999_Eur.J.Pharmacol_382_217
Author(s) : Christopoulos A , Parsons AM , Lew MJ , El-Fakahany EE
Ref : European Journal of Pharmacology , 382 :217 , 1999
Abstract :
PubMedSearch : Christopoulos_1999_Eur.J.Pharmacol_382_217
PubMedID: 10556673

Title : Positive effects of allosteric modulators on the binding properties and the function of muscarinic acetylcholine receptors - Tucek_1998_J.Physiol.Paris_92_241
Author(s) : Tucek S , Jakubik J , Dolezal V , El-Fakahany EE
Ref : Journal de Physiologie (Paris) , 92 :241 , 1998
Abstract :
PubMedSearch : Tucek_1998_J.Physiol.Paris_92_241
PubMedID: 9789816

Title : On the unique binding and activating properties of xanomeline at the M1 muscarinic acetylcholine receptor - Christopoulos_1998_Mol.Pharmacol_53_1120
Author(s) : Christopoulos A , Pierce TL , Sorman JL , El-Fakahany EE
Ref : Molecular Pharmacology , 53 :1120 , 1998
Abstract :
PubMedSearch : Christopoulos_1998_Mol.Pharmacol_53_1120
PubMedID: 9614217

Title : Poster: Evidence for the presence of two sites for classical ligands on muscarinic receptors -
Author(s) : Tucek S , Jakubik J , Bacakova L , El-Fakahany EE
Ref : Life Sciences , 60 :1174 , 1997
PubMedID:

Title : Novel persistent activation of muscarinic M1 receptors by xanomeline - Christopoulos_1997_Eur.J.Pharmacol_334_R3
Author(s) : Christopoulos A , El-Fakahany EE
Ref : European Journal of Pharmacology , 334 :R3 , 1997
Abstract :
PubMedSearch : Christopoulos_1997_Eur.J.Pharmacol_334_R3
PubMedID: 9346340

Title : Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors - Jakubik_1997_Mol.Pharmacol_52_172
Author(s) : Jakubik J , Bacakova L , El-Fakahany EE , Tucek S
Ref : Molecular Pharmacology , 52 :172 , 1997
Abstract :
PubMedSearch : Jakubik_1997_Mol.Pharmacol_52_172
PubMedID: 9224827

Title : Activation of muscarinic acetylcholine receptors via their allosteric binding sites - Jakubik_1996_Proc.Natl.Acad.Sci.U.S.A_93_8705
Author(s) : Jakubik J , Bacakova L , Lisa V , El-Fakahany EE , Tucek S
Ref : Proc Natl Acad Sci U S A , 93 :8705 , 1996
Abstract :
PubMedSearch : Jakubik_1996_Proc.Natl.Acad.Sci.U.S.A_93_8705
PubMedID: 8710935

Title : Poster: Differential coupling of various muscarinic receptor subtypes to activation of nitric oxide synthase -
Author(s) : El-Fakahany EE , Wang SZ , Zhu SZ
Ref : Life Sciences , 56(11-12) :1033 , 1995
PubMedID:

Title : Poster: Allosteric interactions between alcuronium and ligands binding to the classical binding site on cardiac muscarinic receptors -
Author(s) : Tucek S , Proska J , Hejnova L , El-Fakahany EE
Ref : Life Sciences , 56(11-12) :1009 , 1995
PubMedID:

Title : Subtype selectivity of the positive allosteric action of alcuronium at cloned M1-M5 muscarinic acetylcholine receptors - Jakubik_1995_J.Pharmacol.Exp.Ther_274_1077
Author(s) : Jakubik J , Bacakova L , El-Fakahany EE , Tucek S
Ref : Journal of Pharmacology & Experimental Therapeutics , 274 :1077 , 1995
Abstract :
PubMedSearch : Jakubik_1995_J.Pharmacol.Exp.Ther_274_1077
PubMedID: 7562472

Title : Poster: Comparison of muscarinic receptor-mediated activation of cyclic GMP synthesis and nitric oxide release in a neuronal clone -
Author(s) : El-Fakahany EE , Hu J
Ref : Life Sciences , 52(5-6) :566 , 1993
PubMedID:

Title : Effects of tacrine on brain muscarinic-receptor-mediated second-messenger signals - Kiefer-Day_1993_Pharmacology_47_98
Author(s) : Kiefer-Day JS , Abdallah ES , Forray C , Lee NH , Kim ON , El-Fakahany EE
Ref : Pharmacology , 47 :98 , 1993
Abstract :
PubMedSearch : Kiefer-Day_1993_Pharmacology_47_98
PubMedID: 8395061

Title : Modulation by certain conserved aspartate residues of the allosteric interaction of gallamine at the m1 muscarinic receptor - Lee_1992_J.Pharmacol.Exp.Ther_262_312
Author(s) : Lee NH , Hu J , El-Fakahany EE
Ref : Journal of Pharmacology & Experimental Therapeutics , 262 :312 , 1992
Abstract :
PubMedSearch : Lee_1992_J.Pharmacol.Exp.Ther_262_312
PubMedID: 1625205

Title : Comparison of the concentration of messenger RNA encoding four muscarinic receptor subtypes in control and Alzheimer brains - Wang_1992_Brain.Res.Mol.Brain.Res_16_64
Author(s) : Wang SZ , Zhu SZ , Mash DC , El-Fakahany EE
Ref : Brain Research Mol Brain Res , 16 :64 , 1992
Abstract :
PubMedSearch : Wang_1992_Brain.Res.Mol.Brain.Res_16_64
PubMedID: 1334201

Title : Complex allosteric modulation of cardiac muscarinic receptors by protamine: potential model for putative endogenous ligands - Hu_1992_Mol.Pharmacol_42_311
Author(s) : Hu J , Wang SZ , Forray C , El-Fakahany EE
Ref : Molecular Pharmacology , 42 :311 , 1992
Abstract :
PubMedSearch : Hu_1992_Mol.Pharmacol_42_311
PubMedID: 1513329

Title : Lack of intrinsic activity and significant subtype selectivity of SR 95639A at muscarinic receptors - Mohamed_1992_Eur.J.Pharmacol_227_181
Author(s) : Mohamed AS , Forray C , Aly MH , El-Fakahany EE
Ref : European Journal of Pharmacology , 227 :181 , 1992
Abstract :
PubMedSearch : Mohamed_1992_Eur.J.Pharmacol_227_181
PubMedID: 1330650

Title : Muscarinic receptor function and acetylcholinesterase activity after chronic administration of tacrine to mice at therapeutic drug concentrations - Kiefer-Day_1992_Pharmacology_44_71
Author(s) : Kiefer-Day JS , El-Fakahany EE
Ref : Pharmacology , 44 :71 , 1992
Abstract :
PubMedSearch : Kiefer-Day_1992_Pharmacology_44_71
PubMedID: 1315062

Title : Allosteric antagonists of the muscarinic acetylcholine receptor -
Author(s) : Lee NH , El-Fakahany EE
Ref : Biochemical Pharmacology , 42 :199 , 1991
PubMedID: 1859442

Title : Allosteric interactions at the m1, m2 and m3 muscarinic receptor subtypes - Lee_1991_J.Pharmacol.Exp.Ther_256_468
Author(s) : Lee NH , El-Fakahany EE
Ref : Journal of Pharmacology & Experimental Therapeutics , 256 :468 , 1991
Abstract :
PubMedSearch : Lee_1991_J.Pharmacol.Exp.Ther_256_468
PubMedID: 1993991

Title : The presence of an M4 subtype muscarinic receptor in the bovine adrenal medulla revealed by mRNA and receptor binding analyses - Fernando_1991_Eur.J.Pharmacol_207_297
Author(s) : Fernando JC , Abdallah EA , Evinger M , Forray C , El-Fakahany EE
Ref : European Journal of Pharmacology , 207 :297 , 1991
Abstract :
PubMedSearch : Fernando_1991_Eur.J.Pharmacol_207_297
PubMedID: 1723686

Title : High-affinity activation by paraoxon of a muscarinic receptor subtype in rat brain striatum - Jett_1991_Pestic.Biochem.Physiol_39_149
Author(s) : Jett DA , Abdallah EAM , El-Fakahany EE , Eldefrawi ME , Eldefrawi AT
Ref : Pesticide Biochemistry and Physiology , 39 :149 , 1991
Abstract :
PubMedSearch : Jett_1991_Pestic.Biochem.Physiol_39_149
PubMedID:

Title : Muscarinic subtype selectivity of tetrahydroaminoacridine: possible relationship to its capricious efficacy - Kiefer-Day_1991_Eur.J.Pharmacol_203_421
Author(s) : Kiefer-Day JS , Campbell HE , Towles J , El-Fakahany EE
Ref : European Journal of Pharmacology , 203 :421 , 1991
Abstract :
PubMedSearch : Kiefer-Day_1991_Eur.J.Pharmacol_203_421
PubMedID: 1773827

Title : On the involvement of multiple muscarinic receptor subtypes in the activation of phosphoinositide metabolism in rat cerebral cortex - Forray_1990_Mol.Pharmacol_37_893
Author(s) : Forray C , El-Fakahany EE
Ref : Molecular Pharmacology , 37 :893 , 1990
Abstract :
PubMedSearch : Forray_1990_Mol.Pharmacol_37_893
PubMedID: 2163015

Title : Relationship between the partial inhibition of muscarinic receptor-mediated phosphoinositide hydrolysis by phorbol esters and tetrodotoxin in rat cerebral cortex - Abdallah_1990_Brain.Res.Mol.Brain.Res_8_1
Author(s) : Abdallah EA , Forray C , El-Fakahany EE
Ref : Brain Research Mol Brain Res , 8 :1 , 1990
Abstract :
PubMedSearch : Abdallah_1990_Brain.Res.Mol.Brain.Res_8_1
PubMedID: 2166196

Title : Receptor-mediated generation of an EDRF-like intermediate in a neuronal cell line detected by spin trapping techniques - Arroyo_1990_Biochem.Biophys.Res.Commun_170_1177
Author(s) : Arroyo CM , Forray C , El-Fakahany EE , Rosen GM
Ref : Biochemical & Biophysical Research Communications , 170 :1177 , 1990
Abstract :
PubMedSearch : Arroyo_1990_Biochem.Biophys.Res.Commun_170_1177
PubMedID: 1975169

Title : Role of intracellular Ca2+ mobilization in muscarinic and histamine receptor-mediated activation of guanylate cyclase in N1E-115 neuroblastoma cells: assessment of the arachidonic acid release hypothesis - Surichamorn_1990_Mol.Pharmacol_37_860
Author(s) : Surichamorn W , Forray C , El-Fakahany EE
Ref : Molecular Pharmacology , 37 :860 , 1990
Abstract :
PubMedSearch : Surichamorn_1990_Mol.Pharmacol_37_860
PubMedID: 1972774

Title : Parainfluenza virus type 1 reduces the affinity of agonists for muscarinic receptors in guinea-pig lung and heart - Fryer_1990_Eur.J.Pharmacol_181_51
Author(s) : Fryer AD , El-Fakahany EE , Jacoby DB
Ref : European Journal of Pharmacology , 181 :51 , 1990
Abstract :
PubMedSearch : Fryer_1990_Eur.J.Pharmacol_181_51
PubMedID: 2167230

Title : Agonist-induced down-regulation of m1 muscarinic receptors and reduction of their mRNA level in a transfected cell line - Wang_1990_FEBS.Lett_276_185
Author(s) : Wang SZ , Hu JR , Long RM , Pou WS , Forray C , El-Fakahany EE
Ref : FEBS Letters , 276 :185 , 1990
Abstract :
PubMedSearch : Wang_1990_FEBS.Lett_276_185
PubMedID: 2265699

Title : The allosteric binding profile of himbacine: a comparison with other cardioselective muscarinic antagonists - Lee_1990_Eur.J.Pharmacol_179_225
Author(s) : Lee NH , El-Fakahany EE
Ref : European Journal of Pharmacology , 179 :225 , 1990
Abstract :
PubMedSearch : Lee_1990_Eur.J.Pharmacol_179_225
PubMedID: 2364985

Title : Poster: Mediation of phosphinositide metabolism in rat cerebral cortex by M1 and M3 muscarinic receptors -
Author(s) : Forray C , El-Fakahany EE
Ref : Trends in Pharmacological Sciences , Suppl :111 , 1989
PubMedID:

Title : Inhibition of cyclic AMP formation in N1E-115 neuroblastoma cells is mediated by a non-cardiac M2 muscarinic receptor subtype - Surichamorn_1989_Brain.Res_493_320
Author(s) : Surichamorn W , Amrhein CL , Forray C , El-Fakahany EE
Ref : Brain Research , 493 :320 , 1989
Abstract :
PubMedSearch : Surichamorn_1989_Brain.Res_493_320
PubMedID: 2548669

Title : Methoctramine, a cardioselective muscarinic antagonist, stimulates phosphoinositide hydrolysis in rat cerebral cortex - Lee_1989_Eur.J.Pharmacol_167_295
Author(s) : Lee NH , Forray C , El-Fakahany EE
Ref : European Journal of Pharmacology , 167 :295 , 1989
Abstract :
PubMedSearch : Lee_1989_Eur.J.Pharmacol_167_295
PubMedID: 2556288

Title : Different mechanisms of antagonism by methoctramine of two neuronal muscarinic receptor-mediated second messenger responses - Lee_1989_J.Pharmacol.Exp.Ther_251_992
Author(s) : Lee NH , Fryer AD , Forray C , El-Fakahany EE
Ref : Journal of Pharmacology & Experimental Therapeutics , 251 :992 , 1989
Abstract :
PubMedSearch : Lee_1989_J.Pharmacol.Exp.Ther_251_992
PubMedID: 2557423

Title : Characterization of the striatal M2 muscarinic receptor mediating inhibition of cyclic AMP using selective antagonists: a comparison with the brainstem M2 receptor - McKinney_1989_J.Pharmacol.Exp.Ther_250_565
Author(s) : McKinney M , Anderson D , Forray C , El-Fakahany EE
Ref : Journal of Pharmacology & Experimental Therapeutics , 250 :565 , 1989
Abstract :
PubMedSearch : McKinney_1989_J.Pharmacol.Exp.Ther_250_565
PubMedID: 2547939

Title : Poster: Effects of parainfluenza virus on agonist affinity for muscarinic receptors in guinea-pig lung and heart -
Author(s) : Jacoby DB , Fryer AD , El-Fakahany EE
Ref : Trends in Pharmacological Sciences , Suppl :105 , 1989
PubMedID:

Title : Poster: An endogenous factor induces heterogeniety of binding sites for selective muscarinic receptor anfagonists in rat heart -
Author(s) : Fryer AD , El-Fakahany EE
Ref : Trends in Pharmacological Sciences , Suppl :106 , 1989
PubMedID:

Title : Mixed competitive and allosteric antagonism by gallamine of muscarinic receptor-mediated second messenger responses in N1E-115 neuroblastoma cells - Lee_1989_J.Neurochem_53_1300
Author(s) : Lee NH , El-Fakahany EE
Ref : Journal of Neurochemistry , 53 :1300 , 1989
Abstract :
PubMedSearch : Lee_1989_J.Neurochem_53_1300
PubMedID: 2549200

Title : Effects of aging on the interaction of quinuclidinyl benzilate, N-methylscopolamine, pirenzepine, and gallamine with brain muscarinic receptors - Surichamorn_1988_Neurochem.Res_13_1183
Author(s) : Surichamorn W , Kim ON , Lee NH , Lai WS , El-Fakahany EE
Ref : Neurochem Res , 13 :1183 , 1988
Abstract :
PubMedSearch : Surichamorn_1988_Neurochem.Res_13_1183
PubMedID: 3237310

Title : Pseudo-noncompetitive antagonism of muscarinic receptor-mediated cyclic GMP formation and phosphoinositide hydrolysis by pirenzepine - el-Fakahany_1988_J.Pharmacol.Exp.Ther_247_934
Author(s) : El-Fakahany EE , Surichamorn W , Amrhein CL , Stenstrom S , Cioffi CL , Richelson E , McKinney M
Ref : Journal of Pharmacology & Experimental Therapeutics , 247 :934 , 1988
Abstract :
PubMedSearch : el-Fakahany_1988_J.Pharmacol.Exp.Ther_247_934
PubMedID: 2849677

Title : Non-selectivity of amitriptyline for subtypes of brain muscarinic receptors demonstrated in binding and functional assays - McKinney_1988_Eur.J.Pharmacol_157_51
Author(s) : McKinney M , Lee NH , Anderson DJ , Vella-Rountree L , El-Fakahany EE
Ref : European Journal of Pharmacology , 157 :51 , 1988
Abstract :
PubMedSearch : McKinney_1988_Eur.J.Pharmacol_157_51
PubMedID: 2853074

Title : Influence of ligand choice on the apparent binding profile of gallamine to cardiac muscarinic receptors. Identification of three main types of gallamine-muscarinic receptor interactions - Lee_1988_J.Pharmacol.Exp.Ther_246_829
Author(s) : Lee NH , El-Fakahany EE
Ref : Journal of Pharmacology & Experimental Therapeutics , 246 :829 , 1988
Abstract :
PubMedSearch : Lee_1988_J.Pharmacol.Exp.Ther_246_829
PubMedID: 3418516

Title : Charge but not chemical class explains the selective binding of [3H]N-methylscopolamine to a subpopulation of [3H]quinuclidinyl benzilate binding sites in rat cerebral cortex homogenates -
Author(s) : Lee NH , Ramkumar V , El-Fakahany EE
Ref : European Journal of Pharmacology , 130 :153 , 1986
PubMedID: 3780857

Title : Kinetic effects of terbium ions on muscarinic acetylcholine receptors of murine neuroblastoma cells - El-Fakahany_1984_J.Neurochem_42_863
Author(s) : El-Fakahany EE , Pfenning M , Richelson E
Ref : Journal of Neurochemistry , 42 :863 , 1984
Abstract :
PubMedSearch : El-Fakahany_1984_J.Neurochem_42_863
PubMedID: 6319610

Title : Interactions of phencyclidine with crayfish muscle membranes. Sensitivity to calcium channel antagonists and other drugs - El-Fakahany_1984_Mol.Pharmacol_25_369
Author(s) : El-Fakahany EE , Eldefrawi AT , Murphy DL , Aguayo LG , Triggle DJ , Albuquerque EX , Eldefrawi ME
Ref : Molecular Pharmacology , 25 :369 , 1984
Abstract :
PubMedSearch : El-Fakahany_1984_Mol.Pharmacol_25_369
PubMedID: 6328263

Title : Lanthanum binding to murine neuroblastoma cells -
Author(s) : El-Fakahany EE , Lopez JR , Richelson E
Ref : Journal of Neurochemistry , 40 :1687 , 1983
PubMedID: 6854326

Title : Antagonism by antidepressants of muscarinic acetylcholine receptors of human brain - El-Fakahany_1983_Br.J.Pharmacol_78_97
Author(s) : El-Fakahany EE , Richelson E
Ref : British Journal of Pharmacology , 78 :97 , 1983
Abstract :
PubMedSearch : El-Fakahany_1983_Br.J.Pharmacol_78_97
PubMedID: 6297650

Title : Effect of some calcium antagonists on muscarinic receptor-mediated cyclic GMP formation - El-Fakahany_1983_J.Neurochem_40_705
Author(s) : El-Fakahany EE , Richelson E
Ref : Journal of Neurochemistry , 40 :705 , 1983
Abstract :
PubMedSearch : El-Fakahany_1983_J.Neurochem_40_705
PubMedID: 6298367

Title : The molecular basis of neurotransmission at the muscarinic receptor -
Author(s) : Richelson E , El-Fakahany EE
Ref : Biochemical Pharmacology , 30 :2887 , 1981
PubMedID: 6274353

Title : Effects of lanthanides on muscarinic acetylcholine receptor function -
Author(s) : El-Fakahany EE , Richelson E
Ref : Molecular Pharmacology , 19 :282 , 1981
PubMedID: 6262619

Title : Phenoxybenzamine and dibenamine interactions with calcium channel effectors of the muscarinic receptor -
Author(s) : El-Fakahany EE , Richelson E
Ref : Molecular Pharmacology , 20 :519 , 1981
PubMedID: 6276712

Title : Involvement of calcium channels in short-term desensitization of muscarinic receptor-mediated cyclic GMP formation in mouse neuroblastoma cells - El-Fakahany_1980_Proc.Natl.Acad.Sci.U.S.A_77_6897
Author(s) : El-Fakahany EE , Richelson E
Ref : Proc Natl Acad Sci U S A , 77 :6897 , 1980
Abstract :
PubMedSearch : El-Fakahany_1980_Proc.Natl.Acad.Sci.U.S.A_77_6897
PubMedID: 6256769

Title : Regulation of muscarinic receptor-mediated cyclic GMP synthesis by cultured mouse neuroblastoma cells - El-Fakahany_1980_J.Neurochem_35_941
Author(s) : El-Fakahany EE , Richelson E
Ref : Journal of Neurochemistry , 35 :941 , 1980
Abstract :
PubMedSearch : El-Fakahany_1980_J.Neurochem_35_941
PubMedID: 6109003

Title : Temperature dependence of muscarinic acetylcholine receptor activation, desensitization, and resensitization -
Author(s) : El-Fakahany EE , Richelson E
Ref : Journal of Neurochemistry , 34 :1288 , 1980
PubMedID: 6246206